A novel approach to evaluate the effects of artificial bone focal lesion on the three-dimensional strain distributions within the vertebral body

Researchers from our MultiSim project have had a paper on ‘A novel approach to evaluate the effects of artificial bone focal lesion on the three-dimensional strain distributions within the vertebral body’ published in PlosOne.

Workflow of the image processing
Workflow of the image processing

Evaluation of strength of the bone affected by the presence of metastases is fundamental to assess the fracture risk. This work proposes a method to evaluate the variations of strain distributions due to metastatic lesions within the vertebra.

Five porcine vertebrae were tested in compression inside a micro computed tomography scanner. Principal strains were computed within the bone by means of digital volume correlation (BoneDVC).

All intact specimens showed a consistent strain distribution. The artificial lesion generally doubled the strain in the middle portion of the specimen, probably due to stress concentrations close to the defect.

In conclusion, a robust method was developed and will be used to improve clinical assessment of fracture risk in metastatic spines.

Read more: /multisim-insigneo/publications/blog

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