Dr Hannah Crane

BMedSci, BDS, MFDS, FHEA, MSc, PhD

School of Clinical Dentistry

NIHR Academic Clinical Lecturer in Oral and Maxillofacial Pathology

Hannah Crane
Profile picture of Hannah Crane
h.crane@sheffield.ac.uk

Full contact details

Dr Hannah Crane
School of Clinical Dentistry
19 Claremont Crescent
91Ö±²¥
S10 2TA
Profile

Dr Crane was appointed as an NIHR Academic Clinical Lecturer in Oral and Maxillofacial Pathology in December 2023, having recently completed a Wellcome funded Clinical PhD Fellowship investigating treatment resistance in Head and Neck Cancer. 

Hannah graduated from the University of 91Ö±²¥ in 2014, her research interests being sparked whilst undertaking an intercalated BMedSci. After graduation, she completed Dental Foundation Training in South Manchester and Dental Core Training posts in Restorative Dentistry, Oral Medicine and Oral and Maxillofacial Surgery. During this time she successfully obtained a Membership of the Faculty of Dental Surgery (MFDS) from the Royal College of Surgeons Edinburgh. She was appointed as an Academic Clinical Fellow in Oral and Maxillofacial Pathology in 2017 and in 2020 completed a Masters in Clinical Research with Distinction.

Research interests

During her Clinical PhD Fellowship, Dr Crane undertook laboratory research investigating DNA damage in chemotherapy-resistant Head and Neck Cancer. Head and Neck Cancer is associated with significant morbidity and current treatments frequently result in the development of resistance, which can be extremely challenging to treat. She has experience in a broad range of molecular biology techniques, alongside data analysis skills including image analysis using publicly available software such as QuPath and ImageJ. She is also interested in the use of next-generation sequencing to understand complex biological problems. 

Dr Crane is passionate about patient and public involvement in research. She regularly involves patients and the public in the development and dissemination of her research. In 2021, she developed an activity for a patient and public event entitled the Pop-Up University, and in collaboration with MakerFutures, she developed activities designed to engage the public about DNA damage and repair.

Publications

Journal articles

  • McCormick ZJJ, Crane H & Brierley D (2024) . Dental Update, 51(10), 703-706. RIS download Bibtex download
  • Crane H, Walsh H & Hunter KD (2024) . Diagnostic Histopathology, 30(3), 170-178. RIS download Bibtex download
  • Walsh H, Crane H & Hunter KD (2022) . Diagnostic Histopathology, 28(5), 217-227. RIS download Bibtex download
  • Karyka E, Berrueta Ramirez N, Webster CP, Marchi PM, Graves EJ, Godena VK, Marrone L, Bhargava A, Ray S, Ning K , Crane H et al (2022) . Life Science Alliance, 5(8). RIS download Bibtex download
  • Crane H, Karbhari B, Hughes D, Orr R & Brierley D (2021) . Head and Neck Pathology, 15, 1041-1046. RIS download Bibtex download
  • Radhakrishnan R, Crane HL, Daigneault M, Padam KSR & Hunter KD (2021) . Cancers, 13(16). RIS download Bibtex download
  • Walsh H, Crane H, Lee NJ & Brierley DJ (2021) . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 132(1), e50-e51. RIS download Bibtex download
  • Crane H, Walsh H, Tailor A & Hunter K (2021) . Diagnostic Histopathology, 27(5), 182-190. RIS download Bibtex download
  • Niklander SE, Crane HL, Darda L, Lambert DW & Hunter KD (2021) . Journal of Cell Science, 134(4). RIS download Bibtex download
  • Niklander SE, Crane HL, Darda L, Lambert DW & Hunter KD (2020) . RIS download Bibtex download
  • Crane H, Da Forno P, Kyriakidou E, Speight PM & Hunter KD (2020) . Head and Neck Pathology, 14(2), 381-385. RIS download Bibtex download
  • Niklander MS, Crane MH, Lambert DD & Hunter PK (2019) . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 128(1), e82-e82. RIS download Bibtex download
  • Crane H, Mustafa S, Tahir F & Brierley DJ (2019) . Oral Surgery, 12(4), 309-312. RIS download Bibtex download
  • Brierley DJ, Crane H & Hunter KD (2019) . Head and Neck Pathology, 13(1), 103-113. RIS download Bibtex download
  • Siriwardena BSMS, Crane H, O'Neill N, Abdelkarim R, Brierley DJ, Franklin CD, Farthing PM, Speight PM & Hunter KD (2019) . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 127(2), 151-166. RIS download Bibtex download
  • (2017) . International Journal of Paediatric Dentistry, 27(S1), 42-53. RIS download Bibtex download
  • Crane H, Carter A & Andresen E (2017) . Oral Surgery, 10(4), 239-242. RIS download Bibtex download
  • Crane H, Young RJ, Fernando MS & Griffin J () . Journal of Clinical Pathology. RIS download Bibtex download
  • Hendawi NY, Crane HL, Mehanna H, Bolt R, Lambert DW & Hunter KD () . Frontiers in Oral Health, 5. RIS download Bibtex download

Conference proceedings papers

  • Crane H, Foran B, Tahir F, Joyce H, El-Khamisy S & Hunter K (2021) . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 132(1) (pp e15-e15) RIS download Bibtex download
  • Niklander S, Crane H, Lambert D & Hunter K (2017) Interleukin 1 receptor antagonist (IL-1RA) expression is progressively lost in oral dysplasia and oral squamous cell carcinoma but the phenotypic consequences are not clear. CYTOKINE, Vol. 100 (pp 185-185) RIS download Bibtex download

Preprints

  • Crane H, Carr I, Hunter KD & El-Khamisy SF (2024) , Cold Spring Harbor Laboratory. RIS download Bibtex download
Teaching activities

Dr Crane successfully completed a PGCert in Teaching and Learning in Clinical Practice at Edgehill University in 2018 and was subsequently awarded FHEA. She teaches pathology to undergraduate and postgraduate students through lectures, case seminars and virtual microscopy sessions.

She is also involved in the training of postgraduate dentists and facilitates a course for Dental Foundation Trainees on Head and Neck Cancer alongside delivering a study day for Dental Core Trainees on Effective Poster Design.

Professional activities and memberships
  • Oral and Maxillofacial Pathology Representative for the Speciality Advisory Committee for the Additional Dental Specialties (SACADS) (November 2022 to present)
  • Junior Doctor Forum (JDF) Representative at 91Ö±²¥ Teaching Hospitals (July 2022 to present)
  • Member of the British Society for Oral and Maxillofacial Pathology (BSOMP)
  • Member of The Pathological Society of Great Britain and Ireland 
  • Member of the European Society of Pathology (ESP)
  • Member of British Association for Cancer Research (BACR)
  • Reviewer for npj Precision Oncology, Oral Surgery, BMJ case reports and Frontiers of Oral and Maxillofacial Medicine. 
Clinical

Dr Crane is undertaking clinical academic specialist training in Oral and Maxillofacial Pathology, routinely completing macroscopic dissection and reporting of specimens from the head and neck under the supervision of consultant colleagues. She is involved in the teaching of dental core trainees and junior registrars within the department.