Professor Mike Williamson

School of Biosciences

Personal Chair

Professor Mike Williamson
Profile picture of Professor Mike Williamson
m.williamson@sheffield.ac.uk
+44 114 222 4224

Full contact details

Professor Mike Williamson
School of Biosciences
Firth Court
Western Bank
91直播
S10 2TN
Profile

My research concentrates on protein structure and function, mainly by means of NMR, and is described in more detail below.

I also teach NMR and protein structure, signalling, membranes and molecular motors, as well as numerical and statistical methods. I was a reviewer for the HEFCE QAA Molecular Biosciences reviews in 1998-2000, and coincidentally led the MBB submission, in which we got 24/24.

I also headed up the departmental Independent Evaluation of Teaching in 2008, which was also highly complimentary of our teaching. I have been involved in a number of University committees, mostly on admissions, finance and personnel.

I was (2009-2011) Chair of the UK ; also (2009-2012) Chair of the Biochemical Society theme panel II (Molecular structure and function); (2009-2013) a member of BBSRC Committee D (Molecules, Cells and Industrial Biotechnology); (2005-2009) secretary of ; and (2018-) a member of Council of the .

I was on sabbatical in Osaka, Japan from September 2008 until September 2009, mainly to write a book, entitled , published by Garland Press in July 2011 and available online and in all good bookshops. Also available in Italian and Japanese translations.

Career history

  • 1975-1978 Natural Sciences, Clare College, Cambridge University (I)
  • 1978-1981 PhD "Structural Studies on Some Antibiotics", supervised by Dudley Williams
  • 1981-1984 Junior Research Fellow, Churchill College, Cambridge
  • 1992-1983 SERC/NATO overseas research fellow, ETH Z眉rich, with Kurt W眉thrich
  • 1984-1990 Team leader, Bio-NMR, Roche Products Ltd, Welwyn Garden City
  • 1990-current University of 91直播 (appointed Professor in 2001)
  • 2017-2021 Head of Department of Molecular Biology and Biotechnology
  • 1995 Fellow of the Royal Society of Chemistry and chartered chemist
  • 1997 Japan Society for the Promotion of Science (JSPS) invitation fellow
  • 2001 ScD, University of Cambridge
  • 2008-9 Visiting professor, Kinki University, Japan
  • 2009 Visiting professor, Osaka University, Japan
  • 2015 Special invited professor, Kyoto University, Japan
Research interests

During my PhD I used NMR to look at the structure and interactions of antibiotics mainly related to, still a vital drug in the constant battle against bacterial drug resistance. This led to an interest in the NOE, where I worked first on 1D NOEs, showing that by using a viscous solvent you can make small molecules behave like bigger ones, and determined the definitive structure of vancomycin.

Around this time, W眉thrich was developing 2D NMR as a way of studying proteins, so after my PhD I got a research fellowship to work in his lab, where I was lucky enough to work on the first NMR structure of a globular protein (see his 2002 Nobel Prize lecture).

Since then, I have worked both on NMR methodology and on determination of protein structures by NMR. In methodology, I have worked in four main areas:

  • The nuclear Overhauser effect (NOE)
  • Chemical shifts in proteins
  • Relaxation
  • Study of proteins using high pressure
Publications

Show: Featured publications All publications

Journal articles

  • Williamson MP (2024) . Life, 14(5). RIS download Bibtex download
  • Williamson MP (2023) . Life, 13(4). RIS download Bibtex download
  • Hobbs B, Drant J & Williamson MP (2022) . Journal of Biomolecular NMR, 76(4), 153-163. RIS download Bibtex download
  • Fowler NJ & Williamson MP (2022) . Structure, 30(7), 925-933.e2. RIS download Bibtex download
  • Fowler NJ, Sljoka A & Williamson MP (2021) . Structure, 29(12), 1430-1439.e2. RIS download Bibtex download
  • Southam HM, Williamson MP, Chapman JA, Lyon RL, Trevitt CR, Henderson PJF & Poole RK (2021) . Antioxidants, 10(6). RIS download Bibtex download
  • Fowler NJ, Sljoka A & Williamson MP (2020) . Nature Communications, 11(-), ---. RIS download Bibtex download
  • Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Saba艂a I, Williamson MP, Lovering AL & Mesnage S (2019) . Nature Chemical Biology. RIS download Bibtex download
  • Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M , Williamson MP et al (2018) . Redox Biology, 18, 114-123. RIS download Bibtex download
  • Bye JW, Baxter NJ, Hounslow AM, Falconer RJ & Williamson MP (2016) . ACS Omega, 1(4), 669-679. RIS download Bibtex download
  • Mesnage S, Dellarole M, Baxter NJ, Rouget J-B, Dimitrov JD, Wang N, Fujimoto Y, Hounslow AM, Lacroix-Desmazes S, Fukase K , Foster SJ et al (2014) . Nat Commun, 5, 4269. RIS download Bibtex download
  • Williamson MP, Hounslow AM, Ford J, Fowler K, Hebditch M & Hansen PE (2013) . Chem Commun (Camb), 49(84), 9824-9826. RIS download Bibtex download
  • Williamson MP (2013) . Prog Nucl Magn Reson Spectrosc, 73, 1-16. RIS download Bibtex download
  • Kitahara R, Hata K, Li H, Williamson MP & Akasaka K (2013) . Progress in Nuclear Magnetic Resonance Spectroscopy, 71, 35-58. RIS download Bibtex download
  • Wilton DJ, Kitahara R, Akasaka K, Pandya MJ & Williamson MP (2009) . Biophys J, 97(5), 1482-1490. RIS download Bibtex download
  • J枚bstl E, O'Connell J, Fairclough JPA & Williamson MP (2004) . Biomacromolecules, 5(3), 942-949. RIS download Bibtex download
  • Charlton AJ, Baxter NJ, Khan ML, Moir AJG, Haslam E, Davies AP & Williamson MP (2002) . J Agric Food Chem, 50(6), 1593-1601. RIS download Bibtex download
  • Kay BK, Williamson MP & Sudol P (2000) The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J, 14(2), 231-241. RIS download Bibtex download
  • Baxter NJ & Williamson MP (1997) . J Biomol NMR, 9(4), 359-369. RIS download Bibtex download
  • Williamson MP (1994) . Biochem J, 297 ( Pt 2), 249-260. RIS download Bibtex download
  • WILLIAMSON MP, HAVEL TF & WUTHRICH K (1985) SOLUTION CONFORMATION OF PROTEINASE INHIBITOR-IIA FROM BULL SEMINAL PLASMA BY H-1 NUCLEAR MAGNETIC-RESONANCE AND DISTANCE GEOMETRY. J MOL BIOL, 182(2), 295-315. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1981) STRUCTURE REVISION OF THE ANTIBIOTIC VANCOMYCIN - THE USE OF NUCLEAR OVERHAUSER EFFECT DIFFERENCE SPECTROSCOPY. J AM CHEM SOC, 103(22), 6580-6585. RIS download Bibtex download

All publications

Books

  • Williamson M (2012) How Proteins Work. Garland Science. RIS download Bibtex download
  • Williamson MP (2009) . RIS download Bibtex download
  • Neuhaus D & Williamson MP (1989) The Nuclear Overhauser Effect in Structural and Conformational Analysis. Wiley. RIS download Bibtex download

Journal articles

  • Davis JL, Norwood JS, Smith RE, O'Dea F, Chellappa K, Rowe ML, Williamson MP, Stafford GP, Vinogradov E, Maes E , Gu茅rardel Y et al (2025) . Carbohydrate Polymers, 347, 122686-122686. RIS download Bibtex download
  • Williamson MP (2024) . Life, 14(5). RIS download Bibtex download
  • Davis JL, Norwood JS, Smith RE, O'Dea F, Chellappa K, Rowe ML, Williamson MP, Stafford GP, Vinogradov E, Maes E , Gu茅rardel Y et al (2024) . Carbohydrate Polymers, 122983-122983. RIS download Bibtex download
  • Galley NF, Greetham D, Alam谩n-Z谩rate MG, Williamson MP, Evans CA, Spittal WD, Buddle JE, Freeman J, Davis GL, Dickman MJ , Wilcox MH et al (2024) . Journal of Biological Chemistry, 300(1), 105529-105529. RIS download Bibtex download
  • Asakura T & Williamson MP (2023) . International Journal of Biological Macromolecules, 245, 125537-125537. RIS download Bibtex download
  • Fowler NJ, Albalwi MF, Lee S, Hounslow AM & Williamson MP (2023) . Structure, 31(8), 975-986.e3. RIS download Bibtex download
  • Williamson MP (2023) . Life, 13(4). RIS download Bibtex download
  • Hassan MU & Williamson MP (2023) . Saudi Journal of Biological Sciences, 30(2). RIS download Bibtex download
  • Hobbs B, Drant J & Williamson MP (2022) . Journal of Biomolecular NMR, 76(4), 153-163. RIS download Bibtex download
  • Davis JL, Hounslow AM, Baxter NJ, Mesnage S & Williamson MP (2022) . Biomolecular NMR Assignments, 1-5. RIS download Bibtex download
  • Abosamaha A, Williamson MP & Gilmour DJ (2022) . Access Microbiology, 4(5). RIS download Bibtex download
  • Fowler NJ & Williamson MP (2022) . Structure, 30(7), 925-933.e2. RIS download Bibtex download
  • Fowler NJ, Sljoka A & Williamson MP (2021) . Structure, 29(12), 1430-1439.e2. RIS download Bibtex download
  • Southam HM, Williamson MP, Chapman JA, Lyon RL, Trevitt CR, Henderson PJF & Poole RK (2021) . Antioxidants, 10(6). RIS download Bibtex download
  • Hassan MU, Nayab H, Shafique F, Williamson MP, Almansouri TS, Asim N, Shafi N, Attacha S, Khalid M, Ali N & Akbar N (2020) . BioMed Research International, 2020, 1-17. RIS download Bibtex download
  • Fowler NJ, Sljoka A & Williamson MP (2020) . Nature Communications, 11(-), ---. RIS download Bibtex download
  • Asakura T, Ogawa T, Naito A & Williamson MP (2020) . International Journal of Biological Macromolecules, 164, 3974-3983. RIS download Bibtex download
  • Hassan MU, Nayab H, Rehman TU, Williamson MP, Haq KU, Shafi N & Shafique F (2020) . BioMed Research International, 2020. RIS download Bibtex download
  • Iwakawa N, Baxter NJ, Wai DCC, Fowler NJ, Morales RAV, Sugase K, Norton RS & Williamson MP (2019) . Scientific Reports, 9(1). RIS download Bibtex download
  • Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Saba艂a I, Williamson MP, Lovering AL & Mesnage S (2019) . Nature Chemical Biology. RIS download Bibtex download
  • Wakamoto T, Ikeya T, Kitazawa S, Baxter NJ, Williamson MP & Kitahara R (2019) . Protein Science, 28(11), 1993-2003. RIS download Bibtex download
  • Smith RE, Salamaga B, Szkuta P, Hajdamowicz N, Prajsnar TK, Bulmer GS, Fontaine T, Ko艂odziejczyk J, Herry J-M, Hounslow AM , Williamson MP et al (2019) . PLoS Pathogens , 15(5). RIS download Bibtex download
  • Williamson MP (2019) . Natural Product Communications, 14(5). RIS download Bibtex download
  • Fairbanks SD, Robertson CC, Keene FR, Thomas JA & Williamson MP (2019) . Journal of the American Chemical Society, 141(11), 4644-4652. RIS download Bibtex download
  • Pandya MJ, Schiffers S, Hounslow AM, Baxter NJ & Williamson MP (2018) . Frontiers in Molecular Biosciences, 5. RIS download Bibtex download
  • Williamson MP & Kitahara R (2018) . Biochimica et Biophysica Acta - Proteins and Proteomics. RIS download Bibtex download
  • Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M , Williamson MP et al (2018) . Redox Biology, 18, 114-123. RIS download Bibtex download
  • Kudhair BK, Hounslow AM, Rolfe MD, Crack JC, Hunt DM, Buxton RS, Smith LJ, Le Brun NE, Williamson MP & Green J (2017) . Nature Communications, 8(1). RIS download Bibtex download
  • Baxter NJ, Zacharchenko T, Barsukov IL & Williamson MP (2017) . Structure, 25(12), 1856-1866. RIS download Bibtex download
  • Heyam A, Coupland CE, D茅gut C, Haley RA, Baxter NJ, Jakob L, Aguiar PM, Meister G, Williamson MP, Lagos D & Plevin MJ (2017) . Nucleic Acids Research, 45(21), 12577-12584. RIS download Bibtex download
  • McNeill A (2017) . PLoS Genetics, 13(8). RIS download Bibtex download
  • Eaton JD & Williamson MP (2017) . Bioscience Reports, 37(3). RIS download Bibtex download
  • Bye JW, Baxter NJ, Hounslow AM, Falconer RJ & Williamson MP (2016) . ACS Omega, 1(4), 669-679. RIS download Bibtex download
  • Yasid NA, Rolfe MD, Green J & Williamson MP (2016) . Royal Society Open Science, 3(8), 160187-160187. RIS download Bibtex download
  • Rawlings AE, Bramble JP, Hounslow AM, Williamson MP, Monnington AE, Cooke DJ & Staniland SS (2016) . Chemistry - A European Journal, 22(23), 7885-7894. RIS download Bibtex download
  • Xu Y, Streets AJ, Hounslow AM, Tran U, Jean-Alphonse F, Needham AJ, Vilardaga J-P, Wessely O, Williamson MP & Ong ACM (2016) . Journal of the American Society of Nephrology, 27(4), 1159-1173. RIS download Bibtex download
  • Hollingshead S, Kope膷n谩 J, Armstrong DR, Bu膷insk谩 L, Jackson PJ, Chen GE, Dickman MJ, Williamson MP, Sobotka R & Hunter CN (2016) . Frontiers in Plant Science, 7. RIS download Bibtex download
  • Xu Y, Ong ACM, Williamson MP & Hounslow AM (2015) . Biomolecular NMR Assignments, 9(2), 369-373. RIS download Bibtex download
  • Asakura T, Okushita K & Williamson MP (2015) . Macromolecules, 48(8), 2345-2357. RIS download Bibtex download
  • Asakura T, Ohata T, Kametani S, Okushita K, Yazawa K, Nishiyama Y, Nishimura K, Aoki A, Suzuki F, Kaji H , Ulrich AS et al (2015) . Macromolecules, 48(1), 28-36. RIS download Bibtex download
  • Williamson MP (2015) , 109-127. RIS download Bibtex download
  • Mesnage S, Dellarole M, Baxter NJ, Rouget J-B, Dimitrov JD, Wang N, Fujimoto Y, Hounslow AM, Lacroix-Desmazes S, Fukase K , Foster SJ et al (2014) . Nat Commun, 5, 4269. RIS download Bibtex download
  • Okushita K, Asano A, Williamson MP & Asakura T (2014) . Macromolecules, 47(13), 4308-4316. RIS download Bibtex download
  • Kitazawa S, Kameda T, Kumo A, Yagi-Utsumi M, Baxter NJ, Kato K, Williamson MP & Kitahara R (2014) . BIOCHEMISTRY, 53(3), 447-449. RIS download Bibtex download
  • Williamson MP (2014) . Progress in Nuclear Magnetic Resonance Spectroscopy. RIS download Bibtex download
  • Wilson T, Costa PJ, F茅lix V, Williamson MP & Thomas JA (2013) . J Med Chem, 56(21), 8674-8683. RIS download Bibtex download
  • Williamson MP, Hounslow AM, Ford J, Fowler K, Hebditch M & Hansen PE (2013) . Chem Commun (Camb), 49(84), 9824-9826. RIS download Bibtex download
  • Williamson MP (2013) . Prog Nucl Magn Reson Spectrosc, 73, 1-16. RIS download Bibtex download
  • Kitahara R, Hata K, Li H, Williamson MP & Akasaka K (2013) . Progress in Nuclear Magnetic Resonance Spectroscopy, 71, 35-58. RIS download Bibtex download
  • Kitazawa S, Kameda T, Yagi-Utsumi M, Sugase K, Baxter NJ, Kato K, Williamson MP & Kitahara R (2013) . Biochemistry, 52(11), 1874-1885. RIS download Bibtex download
  • Moody RG & Williamson MP (2013) . FEBS Open Bio, 3, 71-77. RIS download Bibtex download
  • Kumo A, Kitazawa S, Kameda T, Baxter NJ, Williamson MP & Kitahara R (2013) . Seibutsu Butsuri, 53(supplement1-2), s160. RIS download Bibtex download
  • Williamson MP & Potts JR (2012) . Biochem Soc Trans, 40(5), 945-949. RIS download Bibtex download
  • Kitazawa S, Kameda T, Yagi M, Sugase K, Baxter N, Kato K, Williamson MP & Kitahara R (2012) . Seibutsu Butsuri, 52(supplement), S87-S87. RIS download Bibtex download
  • Asakura T, Okonogi M, Horiguchi K, Aoki A, Sait么 H, Knight DP & Williamson MP (2012) . Angewandte Chemie, 124(5), 1238-1241. RIS download Bibtex download
  • (2012) . Nature Structural & Molecular Biology, 19(9), 854-860. RIS download Bibtex download
  • Asakura T, Okonogi M, Horiguchi K, Aoki A, Saito H, Knight DP & Williamson MP (2012) . ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(5), 1212-1215. RIS download Bibtex download
  • Tomlinson JH & Williamson MP (2012) . J Biomol NMR, 52(1), 57-64. RIS download Bibtex download
  • Trotter EW, Rolfe MD, Hounslow AM, Craven CJ, Williamson MP, Sanguinetti G, Poole RK & Green J (2011) . PLoS ONE, 6(9). RIS download Bibtex download
  • Williamson MP (2011) . ChemInform, 42(18), no-no. RIS download Bibtex download
  • Ullah S, Ishimoto T, Williamson MP & Hansen PE (2011) . J PHYS CHEM B, 115(12), 3208-3215. RIS download Bibtex download
  • Tomlinson JH & Williamson MP (2011) Amide temperature coefficients in the protein G B1 domain. Journal of Biomolecular NMR, 1-8. RIS download Bibtex download
  • Ratcliffe EC, Tunnicliffe RB, Ng IW, Adams PG, Qian P, Holden-Dye K, Jones MR, Williamson MP & Hunter CN (2011) . Biochim Biophys Acta, 1807(1), 95-107. RIS download Bibtex download
  • Williamson MP & Sutcliffe MJ (2010) . Biochem Soc Trans, 38(4), 875-878. RIS download Bibtex download
  • Correia MAS, Abbott DW, Gloster TM, Fernandes VO, Prates JAM, Montanier C, Dumon C, Williamson MP, Tunnicliffe RB, Liu ZY , Flint JE et al (2010) . BIOCHEMISTRY-US, 49(29), 6193-6205. RIS download Bibtex download
  • Tomlinson JH, Green VL, Baker PJ & Williamson MP (2010) . Proteins, 78(14), 3000-3016. RIS download Bibtex download
  • Wilson T, Williamson MP & Thomas JA (2010) . Org Biomol Chem, 8(11), 2617-2621. RIS download Bibtex download
  • Waywell P, Gonzalez V, Gill MR, Adams H, Meijer AJHM, Williamson MP & Thomas JA (2010) . Chemistry - A European Journal, 16(8), 2324-2324. RIS download Bibtex download
  • Waywell P, Gonzalez V, Gill MR, Adams H, Meijer AJHM, Williamson MP & Thomas JA (2010) . Chemistry, 16(8), 2407-2417. RIS download Bibtex download
  • Giamarchi A, Feng S, Rodat-Despoix L, Xu YX, Bubenshchikova E, Newby LJ, Hao JZ, Gaudioso C, Crest M, Lupas AN , Honore E et al (2010) . EMBO J, 29(7), 1176-1191. RIS download Bibtex download
  • Waywell P, Thomas JA & Williamson MP (2010) . Org Biomol Chem, 8(3), 648-654. RIS download Bibtex download
  • Tomlinson JH, Craven CJ, Williamson MP & Pandya MJ (2010) . Proteins, 78(7), 1652-1661. RIS download Bibtex download
  • Long J, Garner TP, Pandya MJ, Craven CJ, Chen P, Shaw B, Williamson MP, Layfield R & Searle MS (2010) . J MOL BIOL, 396(1), 178-194. RIS download Bibtex download
  • Wilton DJ, Kitahara R, Akasaka K, Pandya MJ & Williamson MP (2009) . Biophys J, 97(5), 1482-1490. RIS download Bibtex download
  • Suzuki Y, Takahashi R, Shimizu T, Tansho M, Yamauchi K, Williamson MP & Asakura T (2009) . J PHYS CHEM B, 113(29), 9756-9761. RIS download Bibtex download
  • Wilton DJ, Kitahara R, Akasaka K & Williamson MP (2009) . J Biomol NMR, 44(1), 25-33. RIS download Bibtex download
  • Tomlinson JH, Ullah S, Hansen PE & Williamson MP (2009) . J Am Chem Soc, 131(13), 4674-4684. RIS download Bibtex download
  • Nakazawa Y, Suzuki Y, Williamson MP, Saito H & Asakura T (2009) . CHEM PHYS LIPIDS, 158(1), 54-60. RIS download Bibtex download
  • Williamson MP & Craven CJ (2009) . J Biomol NMR, 43(3), 131-143. RIS download Bibtex download
  • Cioffi M, Hunter CA, Packer MJ, Pandya MJ & Williamson MP (2009) . J Biomol NMR, 43(1), 11-19. RIS download Bibtex download
  • Wilton DJ, Ghosh M, Chary KVA, Akasaka K & Williamson MP (2008) . Nucleic Acids Res, 36(12), 4032-4037. RIS download Bibtex download
  • Wilton DJ, Tunnicliffe RB, Kamatari YO, Akasaka K & Williamson MP (2008) . Proteins, 71(3), 1432-1440. RIS download Bibtex download
  • Bocian W, Kawecki R, Bednarek E, Sitkowski J, Williamson MP, Hansen PE & Kozerski L (2008) . CHEM-EUR J, 14(9), 2788-2794. RIS download Bibtex download
  • Nagy T, Tunnicliffe RB, Higgins LD, Walters C, Gilbert HJ & Williamson MP (2007) . J MOL BIOL, 373(3), 612-622. RIS download Bibtex download
  • Moody RG, Phillips-Jones MK & Williamson MP (2007) . BIOMOL NMR ASSIGM, 1(1), 11-12. RIS download Bibtex download
  • Cicortas Gunnarsson L, Montanier C, Tunnicliffe RB, Williamson MP, Gilbert HJ, Nordberg Karlsson E & Ohlin M (2007) . Biochemical Journal, 406(2), 209-214. RIS download Bibtex download
  • Tunnicliffe RB, Ratcliffe EC, Hunter CN & Williamson MP (2006) . FEBS Lett, 580(30), 6967-6971. RIS download Bibtex download
  • Williamson MP, McCormick TG, Nance CL & Shearer WT (2006) . J Allergy Clin Immunol, 118(6), 1369-1374. RIS download Bibtex download
  • Williamson MP, Suzuki Y, Bourne NT & Asakura T (2006) . Biochem J, 397(3), 483-490. RIS download Bibtex download
  • Laguri C, Stenzel RA, Donohue TJ, Phillips-Jones MK & Williamson MP (2006) . Biochemistry, 45(25), 7872-7881. RIS download Bibtex download
  • J枚bstl E, Howse JR, Fairclough JPA & Williamson MP (2006) . J Agric Food Chem, 54(12), 4077-4081. RIS download Bibtex download
  • Leon-Kempis MDR, Guccione E, Mulholland F, Williamson MP & Kelly DJ (2006) . Mol Microbiol, 60(5), 1262-1275. RIS download Bibtex download
  • Potter CA, Jeong EL, Williamson MP, Henderson PJF & Phillips-Jones MK (2006) . FEBS LETT, 580(13), 3206-3210. RIS download Bibtex download
  • Tunnicliffe RB, Waby JL, Williams RJ & Williamson MP (2005) . Structure, 13(11), 1677-1684. RIS download Bibtex download
  • J枚bstl E, Fairclough JPA, Davies AP & Williamson MP (2005) . J Agric Food Chem, 53(20), 7997-8002. RIS download Bibtex download
  • Flint J, Bolam DN, Nurizzo D, Taylor EJ, Williamson MP, Walters C, Davies GJ & Gilbert HJ (2005) . J BIOL CHEM, 280(25), 23718-23726. RIS download Bibtex download
  • Williamson MP (2005) . Biochem Soc Trans, 33(Pt 3), 503-506. RIS download Bibtex download
  • Exley RM, Shaw J, Mowe E, Sun Y-H, West NP, Williamson M, Botto M, Smith H & Tang CM (2005) . Journal of Experimental Medicine, 201(10), 1637-1645. RIS download Bibtex download
  • Tunnicliffe RB, Bolam DN, Pell G, Gilbert HJ & Williamson MP (2005) . J Mol Biol, 347(2), 287-296. RIS download Bibtex download
  • Bocian W, Kawecki R, Bednarek E, Sitkowski J, Pietrzyk A, Williamson MP, Hansen PE & Kozerski L (2004) . CHEM-EUR J, 10(22), 5776-5787. RIS download Bibtex download
  • J枚bstl E, O'Connell J, Fairclough JPA & Williamson MP (2004) . Biomacromolecules, 5(3), 942-949. RIS download Bibtex download
  • MCCORMICK T (2004) . Journal of Allergy and Clinical Immunology, 113(2), S256-S256. RIS download Bibtex download
  • Nakano E, Williamson MP, Williams NH & Powers HJ (2004) . Biochim Biophys Acta, 1688(1), 33-42. RIS download Bibtex download
  • Laguri C, Phillips-Jones MK & Williamson MP (2003) . Nucleic Acids Res, 31(23), 6778-6787. RIS download Bibtex download
  • Williamson MP (2003) . Proteins, 53(3), 731-739. RIS download Bibtex download
  • Williamson MP, Akasaka K & Refaee M (2003) . Protein Sci, 12(9), 1971-1979. RIS download Bibtex download
  • Abou-Hachem M, Olsson F, Williamson MP, Hreggvidsson GO, Kristjansson JK & Karlsson EN (2003) . BIOCATAL BIOTRANSFOR, 21(4-5), 253-260. RIS download Bibtex download
  • Refaee M, Tezuka T, Akasaka K & Williamson MP (2003) . J Mol Biol, 327(4), 857-865. RIS download Bibtex download
  • Jakeman DL, Ivory AJ, Blackburn GM & Williamson MP (2003) . J Biol Chem, 278(13), 10957-10962. RIS download Bibtex download
  • Williamson MP, Refaee M & Akasaka K (2003) . Seibutsu Butsuri, 43(supplement), S7-S7. RIS download Bibtex download
  • Horsburgh GJ, Atrih A, Williamson MP & Foster SJ (2003) . Biochemistry, 42(2), 257-264. RIS download Bibtex download
  • Pell G, Williamson MP, Walters C, Du H, Gilbert HJ & Bolam DN (2003) . Biochemistry, 42(31), 9316-9323. RIS download Bibtex download
  • Charlton AJ, Haslam E & Williamson MP (2002) . J Am Chem Soc, 124(33), 9899-9905. RIS download Bibtex download
  • Potter CA, Ward A, Laguri C, Williamson MP, Henderson PJF & Phillips-Jones MK (2002) . J MOL BIOL, 320(2), 201-213. RIS download Bibtex download
  • Abou-Hachem M, Karlsson EN, Simpson PJ, Linse S, Sellers P, Williamson MP, Jamieson SJ, Gilbert HJ, Bolam DN & Holst O (2002) . BIOCHEMISTRY-US, 41(18), 5720-5729. RIS download Bibtex download
  • Simpson PJ, Jamieson SJ, Abou-Hachem M, Karlsson EN, Gilbert HJ, Holst O & Williamson MP (2002) . Biochemistry, 41(18), 5712-5719. RIS download Bibtex download
  • Charlton AJ, Baxter NJ, Khan ML, Moir AJG, Haslam E, Davies AP & Williamson MP (2002) . J Agric Food Chem, 50(6), 1593-1601. RIS download Bibtex download
  • Jamieson SJ, Williamson MP, Abou-Hachem M, Nordberg Karlsson E & Simpson PJ (2002) Letter to the Editor: Virtually complete H-1, C-13 and N-15 resonance assignments of the second family 4 xylan binding module of Rhodothermus marinus xylanase 10A. J BIOMOL NMR, 22(2), 187-188. RIS download Bibtex download
  • Williamson MP (2002) Chemical dreams. CHEM BRIT, 38(1), 19-19. RIS download Bibtex download
  • Raghothama S, Eberhardt RY, Simpson P, Wigelsworth D, White P, Hazlewood GP, Nagy T, Gilbert HJ & Williamson MP (2001) . Nat Struct Biol, 8(9), 775-778. RIS download Bibtex download
  • Xie HF, Gilbert HJ, Charnock SJ, Davies GJ, Williamson MP, Simpson PJ, Raghothama S, Fontes CMGA, Dias FMV, Ferreira LMA & Bolam DN (2001) . BIOCHEMISTRY-US, 40(31), 9167-9176. RIS download Bibtex download
  • Leighton MP, Kelly DJ, Williamson MP & Shaw JG (2001) . Microbiology, 147(Pt 6), 1473-1482. RIS download Bibtex download
  • Xie HF, Bolam DN, Nagy T, Szabo L, Cooper A, Simpson PJ, Lakey JH, Williamson MP & Gilbert HJ (2001) . BIOCHEMISTRY-US, 40(19), 5700-5707. RIS download Bibtex download
  • Kozerski L, Mazurek AP, Kawecki R, Bocian W, Krajewski P, Bednarek E, Sitkowski J, Williamson MP, Moir AJG & Hansen PE (2001) A nicked duplex decamer DNA with a PEG(6) tether. NUCLEIC ACIDS RES, 29(5), 1132-1143. RIS download Bibtex download
  • Bolam DN, Xie HF, White P, Simpson PJ, Hancock SM, Williamson MP & Gilbert HJ (2001) Evidence for synergy between family 2b carbohydrate binding modules in Cellulomonas fimi xylanase 11A. BIOCHEMISTRY-US, 40(8), 2468-2477. RIS download Bibtex download
  • Iwadate M, Asakura T, Dubovskii PV, Yamada H, Akasaka K & Williamson MP (2001) Pressure-dependent changes in the structure of the melittin alpha-helix determined by NMR. J BIOMOL NMR, 19(2), 115-124. RIS download Bibtex download
  • Simpson PJ, Xie H, Bolam DN, Gilbert HJ & Williamson MP (2000) . J Biol Chem, 275(52), 41137-41142. RIS download Bibtex download
  • Iwadate M, Nagao E, Williamson MP, Ueki M & Asakura T (2000) Structure determination of [Arg8]vasopressin methylenedithioether in dimethylsulfoxide using NMR. EUR J BIOCHEM, 267(14), 4504-4510. RIS download Bibtex download
  • Conroy MJ, Westerhuis WH, Parkes-Loach PS, Loach PA, Hunter CN & Williamson MP (2000) . J Mol Biol, 298(1), 83-94. RIS download Bibtex download
  • Ponyi T, Szabo L, Nagy T, Orosz L, Simpson PJ, Williamson MP & Gilbert HJ (2000) Trp22, Trp24, and Tyr8 play a pivotal role in the binding of the family 10 cellulose-binding module from Pseudomonas xylanase A to insoluble ligands. BIOCHEMISTRY-US, 39(5), 985-991. RIS download Bibtex download
  • Raghothama S, Simpson PJ, Szab贸 L, Nagy T, Gilbert HJ & Williamson MP (2000) . Biochemistry, 39(5), 978-984. RIS download Bibtex download
  • Kay BK, Williamson MP & Sudol P (2000) The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J, 14(2), 231-241. RIS download Bibtex download
  • Kikuchi J, Asakura T, Hasuda K, Ito T, Ohwaku K, Araki H & Williamson MP (2000) An advantage for use of isotope labeling and NMR chemical shifts to analyze the structure of four homologous IgG-binding domains of staphylococcal protein A. J BIOCHEM BIOPH METH, 42(1-2), 35-47. RIS download Bibtex download
  • Abou Hachem M, Karlsson EN, Bartonek-Roxa E, Raghothama S, Simpson PJ, Gilbert HJ, Williamson MP & Holst O (2000) Carbohydrate-binding modules from a thermostable Rhodothermus marinus xylanase: cloning, expression and binding studies. BIOCHEM J, 345, 53-60. RIS download Bibtex download
  • Kikuchi J, Williamson MP, Shimada K & Asakura T (2000) Structure and dynamics of photosynthetic membrane-bound proteins in Rhodobacter Sphaeroides, studied with solid-state NMR spectroscopy. PHOTOSYNTH RES, 63(3), 259-267. RIS download Bibtex download
  • Charlton AJ, Davis AL, Jones DP, Lewis JR, Davies AP, Haslam E & Williamson MP (2000) The self-association of the black tea polyphenol theaflavin and its complexation with caffeine. J CHEM SOC PERK T 2(2), 317-322. RIS download Bibtex download
  • ABOU HACHEM M, NORDBERG KARLSSON E, BARTONEK-ROX脜 E, RAGHOTHAMA S, SIMPSON PJ, GILBERT HJ, WILLIAMSON MP & HOLST O (2000) . Biochemical Journal, 345(1), 53-53. RIS download Bibtex download
  • Gill J, Rixon JE, Bolam DN, McQueen-Mason S, Simpson PJ, Williamson MP, Hazlewood GP & Gilbert HJ (1999) The type II and X cellulose-binding domains of Pseudomonas xylanase A potentiate catalytic activity against complex substrates by a common mechanism. BIOCHEM J, 342, 473-480. RIS download Bibtex download
  • GILL J, RIXON JE, BOLAM DN, MCQUEEN-MASON S, SIMPSON PJ, WILLIAMSON MP, HAZLEWOOD GP & GILBERT HJ (1999) . Biochemical Journal, 342(2), 473-473. RIS download Bibtex download
  • Simpson PJ, Bolam DN, Cooper A, Ciruela A, Hazlewood GP, Gilbert HJ & Williamson MP (1999) . Structure, 7(7), 853-864. RIS download Bibtex download
  • Ueki M, Ikeo T, Iwadate M, Asakura T, Williamson MP & Slaninova J (1999) Solid phase synthesis and biological activities of [Arg(8)]-vasopressin methylenedithioether. BIOORG MED CHEM LETT, 9(13), 1767-1772. RIS download Bibtex download
  • Atrih A, Bacher G, Allmaier G, Williamson MP & Foster SJ (1999) . J Bacteriol, 181(13), 3956-3966. RIS download Bibtex download
  • Kikuchi J, Asakura T, Loach PA, Parkes-Loach PS, Shimada K, Hunter CN, Conroy MJ & Williamson MP (1999) A light-harvesting antenna protein retains its folded conformation in the absence of protein-lipid and protein-pigment interactions. BIOPOLYMERS, 49(5), 361-372. RIS download Bibtex download
  • Southall SM, Simpson PJ, Gilbert HJ, Williamson G & Williamson MP (1999) . FEBS Lett, 447(1), 58-60. RIS download Bibtex download
  • Iwadate M, Asakura T & Williamson MP (1999) C-alpha and C-beta carbon-13 chemical shifts in proteins from an empirical database. J BIOMOL NMR, 13(3), 199-211. RIS download Bibtex download
  • Furman B, Krajewski P, Kaluza Z, Thurmer R, Voelter W, Kozerski L, Williamson MP & Chmielewski M (1999) Stereochemical model of [2+2]cycloaddition of chlorosulfonyl isocyanate to chiral vinyl ethers. J CHEM SOC PERK T 2(2), 217-224. RIS download Bibtex download
  • Jakeman DL, Bernstein B, Hol W, Williams DM, Williamson MP & Blackburn GM (1999) Highly potent bisphosphonate ligands for phosphoglycerate kinase and protein binding studies. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 146, 533-536. RIS download Bibtex download
  • Baxter NJ, Hosszu LL, Waltho JP & Williamson MP (1998) . J Mol Biol, 284(5), 1625-1639. RIS download Bibtex download
  • Jakeman DL, Ivory AJ, Williamson MP & Blackburn GM (1998) . J Med Chem, 41(23), 4439-4452. RIS download Bibtex download
  • Iwadate M, Asakura T & Williamson MP (1998) The structure of the melittin tetramer at different temperatures - An NOE-based calculation with chemical shift refinement. EUR J BIOCHEM, 257(2), 479-487. RIS download Bibtex download
  • Williams DM, Jakeman DL, Vyle JS, Williamson MP & Blackburn GM (1998) . Bioorg Med Chem Lett, 8(18), 2603-2608. RIS download Bibtex download
  • Atrih A, Z枚llner P, Allmaier G, Williamson MP & Foster SJ (1998) . J Bacteriol, 180(17), 4603-4612. RIS download Bibtex download
  • Nagy T, Simpson P, Williamson MP, Hazlewood GP, Gilbert HJ & Orosz L (1998) All three surface tryptophans in Type IIa cellulose binding domains play a pivotal role in binding both soluble and insoluble ligands. FEBS LETT, 429(3), 312-316. RIS download Bibtex download
  • Bolam DN, Ciruela A, McQueen-Mason S, Simpson P, Williamson MP, Rixon JE, Boraston A, Hazlewood GP & Gilbert HJ (1998) Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity. BIOCHEM J, 331, 775-781. RIS download Bibtex download
  • Bayley MJ, Jones G, Willett P & Williamson MP (1998) . Protein Sci, 7(2), 491-499. RIS download Bibtex download
  • Khan ML, Haslam E & Williamson MP (1997) Structure and conformation of the procyanidin B-2 dimer. MAGN RESON CHEM, 35(12), 854-858. RIS download Bibtex download
  • Kozerski L, Krajewski P, Pupek K, Blackwell PG & Williamson MP (1997) Towards stereochemical and conformational assignment in flexible molecules using NOEs and molecular modelling. J CHEM SOC PERK T 2(9), 1811-1818. RIS download Bibtex download
  • Williamson MP, Le Gal-Co毛ffet MF, Sorimachi K, Furniss CS, Archer DB & Williamson G (1997) . Biochemistry, 36(24), 7535-7539. RIS download Bibtex download
  • Baxter NJ & Williamson MP (1997) . J Biomol NMR, 9(4), 359-369. RIS download Bibtex download
  • Blanchard L, Hunter CN & Williamson MP (1997) . J Biomol NMR, 9(4), 389-395. RIS download Bibtex download
  • Sorimachi K, Le Gal-Co毛ffet MF, Williamson G, Archer DB & Williamson MP (1997) . Structure, 5(5), 647-661. RIS download Bibtex download
  • Baxter NJ, Lilley TH, Haslam E & Williamson MP (1997) . Biochemistry, 36(18), 5566-5577. RIS download Bibtex download
  • Rogers MJ, Xiong X, Ji X, M枚nkk枚nen J, Russell RG, Williamson MP, Ebetino FH & Watts DJ (1997) . Pharm Res, 14(5), 625-630. RIS download Bibtex download
  • Williamson MP & Asakura T (1997) Protein chemical shifts., 60, 53-69. RIS download Bibtex download
  • Asakura T, Demura M, Date T, Miyashita N, Ogawa K & Williamson MP (1997) NMR study of silk I structure of Bombyx mori silk fibroin with N-15- and C-13-NMR chemical shift contour plots. BIOPOLYMERS, 41(2), 193-203. RIS download Bibtex download
  • Williamson MP & Asakura T (1997) . Methods Mol Biol, 60, 53-69. RIS download Bibtex download
  • Mehmood Z, Williamson MP, Kelly DE & Kelly SL (1996) Human cytochrome P450 3A4 is involved in the biotransformation of the herbicide 2,4-dichlorophenoxyacetic acid. ENVIRON TOXICOL PHAR, 2(4), 397-401. RIS download Bibtex download
  • Mehmood Z, Williamson MP, Kelly DE & Kelly SL (1996) . Chemosphere, 33(4), 759-769. RIS download Bibtex download
  • Sorimachi K, Jacks AJ, Le Gal-Co毛ffet MF, Williamson G, Archer DB & Williamson MP (1996) . J Mol Biol, 259(5), 970-987. RIS download Bibtex download
  • Charlton AJ, Baxter NJ, Lilley TH, Haslam E, McDonald CJ & Williamson MP (1996) . FEBS Lett, 382(3), 289-292. RIS download Bibtex download
  • Baxter NJ, Williamson MP, Lilley TH & Haslam E (1996) Stacking interactions between caffeine and methyl gallate. J CHEM SOC FARADAY T, 92(2), 231-234. RIS download Bibtex download
  • Williams DM, Jakeman DL, Vyle JS, Williamson MP & Blackburn GM (1996) Synthesis and kinetic studies of bisubstrate analogues of phosphoglycerate kinase. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 61, S88-S91. RIS download Bibtex download
  • ASAKURA T, TAOKA K, DEMURA M & WILLIAMSON MP (1995) THE RELATIONSHIP BETWEEN AMIDE PROTON CHEMICAL-SHIFTS AND SECONDARY STRUCTURE IN PROTEINS. J BIOMOL NMR, 6(3), 227-236. RIS download Bibtex download
  • Jacks AJ, Sorimachi K, Le Gal-Co毛ffet MF, Williamson G, Archer DB & Williamson MP (1995) . Eur J Biochem, 233(2), 568-578. RIS download Bibtex download
  • Le Gal-Co毛ffet MF, Jacks AJ, Sorimachi K, Williamson MP, Williamson G & Archer DB (1995) . Eur J Biochem, 233(2), 561-567. RIS download Bibtex download
  • KOZERSKI L, KAWECKI R, KRAJEWSKI P, GLUZINSKI P, PUPEK K, HANSEN PE & WILLIAMSON MP (1995) SEARCHING CONFORMATIONAL SPACE IN FLEXIBLE MOLECULES USING NOES AND MOLECULAR MODELING. J ORG CHEM, 60(11), 3533-3538. RIS download Bibtex download
  • Williamson MP, Kikuchi J & Asakura T (1995) . J Mol Biol, 247(4), 541-546. RIS download Bibtex download
  • WILLIAMSON MP, TREVITT C & NOBLE JM (1995) NMR-STUDIES OF DEXTRAN OLIGOMER INTERACTIONS WITH MODEL POLYPHENOLS. CARBOHYD RES, 266(2), 229-235. RIS download Bibtex download
  • BLACKBURN GM, JAKEMAN DL, IVORY AJ & WILLIAMSON MP (1994) SYNTHESIS OF PHOSPHONATE ANALOGS OF 1,3-BISPHOSPHOGLYCERIC ACID AND THEIR BINDING TO YEAST PHOSPHOGLYCERATE KINASE. BIOORG MED CHEM LETT, 4(21), 2573-2578. RIS download Bibtex download
  • Rogers MJ, Ji X, Russell RG, Blackburn GM, Williamson MP, Bayless AV, Ebetino FH & Watts DJ (1994) . Biochem J, 303 ( Pt 1), 303-311. RIS download Bibtex download
  • Luck G, Liao H, Murray NJ, Grimmer HR, Warminski EE, Williamson MP, Lilley TH & Haslam E (1994) . Phytochemistry, 37(2), 357-371. RIS download Bibtex download
  • Murray NJ, Williamson MP, Lilley TH & Haslam E (1994) . Eur J Biochem, 219(3), 923-935. RIS download Bibtex download
  • Williamson MP (1994) . Biochem Soc Trans, 22(1), 140-144. RIS download Bibtex download
  • Murray NJ & Williamson MP (1994) . Eur J Biochem, 219(3), 915-921. RIS download Bibtex download
  • Williamson MP (1994) . Biochem J, 297 ( Pt 2), 249-260. RIS download Bibtex download
  • KIKUCHI J, FUJITA K, WILLIAMSON MP & ASAKURA T (1994) STRUCTURE-ANALYSIS OF PROTEINS BY A COMBINATION OF DISTANCE GEOMETRY CALCULATION AND H-1-NMR CHEMICAL-SHIFT CALCULATION. KOBUNSHI RONBUNSHU, 51(6), 409-413. RIS download Bibtex download
  • CUMMINGS SP, WILLIAMSON MP & GILMOUR DJ (1993) TURGOR REGULATION IN A NOVEL HALOMONAS SPECIES. ARCH MICROBIOL, 160(4), 319-323. RIS download Bibtex download
  • Williamson MP (1993) . Nat Prod Rep, 10(3), 207-232. RIS download Bibtex download
  • Machado RS, Guest JR & Williamson MP (1993) . FEBS Lett, 323(3), 243-246. RIS download Bibtex download
  • WILLIAMSON MP & ASAKURA T (1993) EMPIRICAL COMPARISONS OF MODELS FOR CHEMICAL-SHIFT CALCULATION IN PROTEINS. J MAGN RESON SER B, 101(1), 63-71. RIS download Bibtex download
  • Williamson MP (1993) . Methods Mol Biol, 17, 69-85. RIS download Bibtex download
  • Turner SL, Russell GC, Williamson MP & Guest JR (1993) . Protein Eng, 6(1), 101-108. RIS download Bibtex download
  • Anson M, Blackburn GM, Ivory AJ, Jakeman DL, Littlechild JA & Williamson MP (1993) . ChemPlusChem, 58(s1), 109-112. RIS download Bibtex download
  • WILLIAMSON MP & WALTHO JP (1992) PEPTIDE STRUCTURE FROM NMR. CHEM SOC REV, 21(4), 227-236. RIS download Bibtex download
  • WILLIAMSON MP, MURRAY NJ & WALTHO JP (1992) IMPROVED EXPERIMENTS FOR THE ASSIGNMENT OF CROWDED PEPTIDE SPECTRA. J MAGN RESON, 100(3), 593-597. RIS download Bibtex download
  • Rogers MJ, Russell RG, Blackburn GM, Williamson MP & Watts DJ (1992) . Biochem Biophys Res Commun, 189(1), 414-423. RIS download Bibtex download
  • WILLIAMSON G, BELSHAW NJ, NOEL TR, RING SG & WILLIAMSON MP (1992) O-GLYCOSYLATION AND STABILITY - UNFOLDING OF GLUCOAMYLASE INDUCED BY HEAT AND GUANIDINE-HYDROCHLORIDE. EUR J BIOCHEM, 207(2), 661-670. RIS download Bibtex download
  • ASAKURA T, NIIZAWA Y & WILLIAMSON MP (1992) DETERMINATION OF THE MAGNETIC-ANISOTROPY OF THE OXYGEN ATOM AND H-1 CHEMICAL-SHIFT CALCULATION OF PROTEINS. J MAGN RESON, 98(3), 646-653. RIS download Bibtex download
  • Williamson MP & Asakura T (1992) . FEBS Lett, 302(2), 185-188. RIS download Bibtex download
  • WILLIAMSON G, BELSHAW NJ & WILLIAMSON MP (1992) O-GLYCOSYLATION IN ASPERGILLUS GLUCOAMYLASE - CONFORMATION AND ROLE IN BINDING. BIOCHEM J, 282, 423-428. RIS download Bibtex download
  • Williamson MP, Asakura T, Nakamura E & Demura M (1992) . J Biomol NMR, 2(1), 83-98. RIS download Bibtex download
  • Robbins AH, McRee DE, Williamson M, Collett SA, Xuong NH, Furey WF, Wang BC & Stout CD (1991) . Journal of Molecular Biology, 221(4), 1269-1293. RIS download Bibtex download
  • WILLIAMSON MP & ASAKURA T (1991) CALCULATION OF CHEMICAL-SHIFTS OF PROTONS ON ALPHA CARBONS IN PROTEINS. J MAGN RESON, 94(3), 557-562. RIS download Bibtex download
  • WILLIAMSON MP (1991) NMR IN PROTEIN STUDIES. CHEM BRIT, 27(4), 335-337. RIS download Bibtex download
  • Williamson MP, Davies JS & Thomas WA (1991) . Journal of the Chemical Society, Perkin Transactions 2(5), 601-606. RIS download Bibtex download
  • Williamson MP (1990) . Biopolymers, 29(10-11), 1423-1431. RIS download Bibtex download
  • Derome AE & Williamson MP (1990) . Journal of Magnetic Resonance (1969), 88(1), 177-185. RIS download Bibtex download
  • WILLIAMSON MP (1990) SECONDARY-STRUCTURE DEPENDENT CHEMICAL-SHIFTS IN PROTEINS. BIOPOLYMERS, 29(10-11), 1428-1431. RIS download Bibtex download
  • Williamson MP & Madison VS (1990) . Biochemistry, 29(12), 2895-2905. RIS download Bibtex download
  • Williamson MP (1989) . FEBS Letters, 254(1-2), 171-173. RIS download Bibtex download
  • Williamson MP, Davis PD, Broadhurst MJ & Nixon JS (1989) . Biochim Biophys Acta, 997(1-2), 9-14. RIS download Bibtex download
  • Williamson MP (1989) . J Mol Biol, 206(2), 407-410. RIS download Bibtex download
  • Williamson MP, Humm G & Crisp AJ (1989) . Br J Rheumatol, 28(1), 23-27. RIS download Bibtex download
  • WILLIAMSON MP, HUMM G & CRISP AJ (1989) H-1 NUCLEAR MAGNETIC-RESONANCE INVESTIGATION OF SYNOVIAL-FLUID COMPONENTS IN OSTEO-ARTHRITIS, RHEUMATOID-ARTHRITIS AND TRAUMATIC EFFUSIONS. BRIT J RHEUMATOL, 28(1), 23-27. RIS download Bibtex download
  • ANG S-G, WILLIAMSON MP & WILLIAMS DH (1988) . ChemInform, 19(44). RIS download Bibtex download
  • ANG SG, WILLIAMSON MP & WILLIAMS DH (1988) STRUCTURE ELUCIDATION OF A GLYCOPEPTIDE ANTIBIOTIC, OA-7653. J CHEM SOC PERK T 1(7), 1949-1956. RIS download Bibtex download
  • WILLIAMSON MP & NEUHAUS D (1987) . ChemInform, 18(45). RIS download Bibtex download
  • KEELER J, NEUHAUS D & WILLIAMSON MP (1987) THE NUCLEAR OVERHAUSER EFFECT IN STRONGLY COUPLED SPIN SYSTEMS. J MAGN RESON, 73(1), 45-68. RIS download Bibtex download
  • WILLIAMSON MP (1987) . MAGNETIC RESONANCE IN CHEMISTRY, 25(4), 356-361. RIS download Bibtex download
  • WILLIAMSON MP & NEUHAUS D (1987) SYMMETRY IN NOE SPECTRA. J MAGN RESON, 72(2), 369-375. RIS download Bibtex download
  • WILLIAMSON MP, HANDA BK & HALL MJ (1986) SECONDARY STRUCTURE OF A HERPES-SIMPLEX VIRUS GLYCOPROTEIN-D ANTIGENIC DOMAIN. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 27(5), 562-568. RIS download Bibtex download
  • WILLIAMSON MP, HALL MJ & HANDA BK (1986) . European Journal of Biochemistry, 158(3), 527-536. RIS download Bibtex download
  • WILLIAMSON MP, HAVEL TF & WUTHRICH K (1985) SOLUTION CONFORMATION OF PROTEINASE INHIBITOR-IIA FROM BULL SEMINAL PLASMA BY H-1 NUCLEAR MAGNETIC-RESONANCE AND DISTANCE GEOMETRY. J MOL BIOL, 182(2), 295-315. RIS download Bibtex download
  • Williamson MP & Williams DH (1985) 1 H N.M.R. Studies of the structure of ristocetin a and of its complexes with bacterial cell wall analogues in aqueous solution. Journal of the Chemical Society, Perkin Transactions 1, 949-956. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1985) H-1-NMR STUDIES OF THE STRUCTURE OF RISTOCETIN-A AND OF ITS COMPLEXES WITH BACTERIAL-CELL WALL ANALOGS IN AQUEOUS-SOLUTION. J CHEM SOC PERK T 1(5), 949-956. RIS download Bibtex download
  • BARNA JCJ, WILLIAMS DH & WILLIAMSON MP (1985) STRUCTURAL FEATURES THAT AFFECT THE BINDING OF TEICOPLANIN, RISTOCETIN-A, AND THEIR DERIVATIVES TO THE BACTERIAL CELL-WALL MODEL N-ACETYL-D-ALANYL-D-ALANINE. J CHEM SOC CHEM COMM(5), 254-256. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1984) HYDROPHOBIC INTERACTIONS AFFECT HYDROGEN-BOND STRENGTHS IN COMPLEXES BETWEEN PEPTIDES AND VANCOMYCIN OR RISTOCETIN. EUR J BIOCHEM, 138(2), 345-348. RIS download Bibtex download
  • WUTHRICH K, STROP P, EBINA S & WILLIAMSON MP (1984) A GLOBULAR PROTEIN WITH SLOWER AMIDE PROTON-EXCHANGE FROM AN ALPHA-HELIX THAN FROM ANTIPARALLEL BETA-SHEETS. BIOCHEM BIOPH RES CO, 122(3), 1174-1178. RIS download Bibtex download
  • WILLIAMSON MP, WILLIAMS DH & HAMMOND SJ (1984) INTERACTIONS OF VANCOMYCIN AND RISTOCETIN WITH PEPTIDES AS A MODEL FOR PROTEIN-BINDING. TETRAHEDRON, 40(3), 569-577. RIS download Bibtex download
  • WILLIAMSON MP, MARION D & WUTHRICH K (1984) SECONDARY STRUCTURE IN THE SOLUTION CONFORMATION OF THE PROTEINASE INHIBITOR-IIA FROM BULL SEMINAL PLASMA BY NUCLEAR MAGNETIC-RESONANCE. J MOL BIOL, 173(3), 341-359. RIS download Bibtex download
  • WILLIAMSON MP (1983) PURE ABSORPTION PHASE PROTON 2D J-RESOLVED SPECTROSCOPY. J MAGN RESON, 55(3), 471-474. RIS download Bibtex download
  • WILLIAMS DH, WILLIAMSON MP, BUTCHER DW & HAMMOND SJ (1983) DETAILED BINDING-SITES OF THE ANTIBIOTICS VANCOMYCIN AND RISTOCETIN-A - DETERMINATION OF INTERMOLECULAR DISTANCES IN ANTIBIOTIC SUBSTRATE COMPLEXES BY USE OF THE TIME-DEPENDENT NOE. J AM CHEM SOC, 105(5), 1332-1339. RIS download Bibtex download
  • WILLIAMSON MP, GAUVREAU D, WILLIAMS DH & WARING MJ (1982) STRUCTURE AND CONFORMATION OF 14 ANTIBIOTICS OF THE QUINOXALINE GROUP DETERMINED BY H-1-NMR. J ANTIBIOT, 35(1), 62-66. RIS download Bibtex download
  • HAMMOND SJ, WILLIAMSON MP, WILLIAMS DH, BOECK LD & MARCONI GG (1982) ON THE BIOSYNTHESIS OF THE ANTIBIOTIC VANCOMYCIN. J CHEM SOC CHEM COMM(6), 344-346. RIS download Bibtex download
  • Williamson MP & Williams DH (1981) Erratum: Manipulation of the nuclear overhauser effect by the use of a viscous solvent: The solution conformation of the antibiotic echinomycin (Journal of the Chemical Society, Chemical Communications (1981) (165)). Journal of the Chemical Society, Chemical Communications(9), 440. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1981) MANIPULATION OF THE NUCLEAR OVERHAUSER EFFECT BY THE USE OF A VISCOUS SOLVENT - THE SOLUTION CONFORMATION OF THE ANTIBIOTIC ECHINOMYCIN. J CHEM SOC CHEM COMM(4), 165-166. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1981) STRUCTURE REVISION OF THE ANTIBIOTIC VANCOMYCIN - THE USE OF NUCLEAR OVERHAUSER EFFECT DIFFERENCE SPECTROSCOPY. J AM CHEM SOC, 103(22), 6580-6585. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1981) A C-13 NUCLEAR MAGNETIC-RESONANCE STUDY OF RISTOCETIN-A AND RISTOCETIN-B AND THEIR DERIVATIVES. J CHEM SOC PERK T 1(5), 1483-1491. RIS download Bibtex download
  • BONGINI A, FEENEY J, WILLIAMSON MP & WILLIAMS DH (1981) ASSIGNMENT OF THE C-13 SPECTRUM OF VANCOMYCIN AND ITS DERIVATIVES. J CHEM SOC PERK T 2(1), 201-206. RIS download Bibtex download
  • WILLIAMSON MP & WILLIAMS DH (1980) A C-13 NMR-STUDY OF THE CARBOHYDRATE PORTION OF RISTOCETIN-A. TETRAHEDRON LETT, 21(43), 4187-4188. RIS download Bibtex download
  • WILLIAMS DH, RAJANANDA V, BOJESEN G & WILLIAMSON MP (1979) STRUCTURE OF THE ANTIBIOTIC RISTOCETIN-A. J CHEM SOC CHEM COMM(20), 906-908. RIS download Bibtex download
  • Trevitt CR, Yashwanth Kumar DR, Fowler NJ & Williamson MP () . Communications Chemistry, 7(1). RIS download Bibtex download
  • Hassan MU, Chaudhuri RR & Williamson MP () . Protein Science. RIS download Bibtex download
  • Makwana MV, Williamson MP, Jackson RFW & Muimo R () . PLOS ONE, 17(9), e0273797-e0273797. RIS download Bibtex download
  • Lyon RF, Southam HM, Trevitt C, Liao C, El-Khamisy S, Poole RK & Williamson MP () . Biochemical Journal. RIS download Bibtex download
  • KOZERSKI L, KRAJEWSKI P, PUPEK K, BLACKWELL PG & WILLIAMSON MP () . ChemInform, 28(51), no-no. RIS download Bibtex download
  • WILLIAMSON MP & WALTHO JP () . ChemInform, 24(12), no-no. RIS download Bibtex download
  • WILLIAMSON MP () . ChemInform, 22(32), no-no. RIS download Bibtex download
  • Makwana MV, van Meurs S, Hounslow AM, Williamson MP, Jackson RFW & Muimo R () . RIS download Bibtex download

Chapters

  • Williamson MP (2019) , Encyclopedia of Analytical Science (pp. 264-271). RIS download Bibtex download
  • Williamson MP (2018) , Modern Magnetic Resonance (pp. 2133-2147). Springer International Publishing RIS download Bibtex download
  • Williamson MP (2018) , Modern Magnetic Resonance (pp. 995-1012). Springer International Publishing RIS download Bibtex download
  • Williamson MP (2018) , Reference Module in Chemistry, Molecular Sciences and Chemical Engineering Elsevier RIS download Bibtex download
  • Williamson MP (2017) , Modern Magnetic Resonance (pp. 1-15). Springer International Publishing RIS download Bibtex download
  • Williamson MP (2017) , Modern Magnetic Resonance (pp. 1-19). Springer International Publishing RIS download Bibtex download
  • Williamson MP (2005) , Encyclopedia of Analytical Science (pp. 342-349). Elsevier RIS download Bibtex download
  • Williamson MP (2005) , Encyclopedia of Analytical Science (pp. V6-342-V6-349). RIS download Bibtex download
  • Haslam E, Williamson MP, Baxter NJ & Charlton AJ (1999) , Phytochemicals in Human Health Protection, Nutrition, and Plant Defense (pp. 289-318). Springer US RIS download Bibtex download
  • Williamson MP, Havel TF & W眉thrich K (1995) , NMR in Structural Biology (pp. 319-339). RIS download Bibtex download
  • Williamson MP () John Wiley & Sons, Ltd RIS download Bibtex download
  • Williamson MP () John Wiley & Sons, Ltd RIS download Bibtex download
  • Williamson MP () , Modern Magnetic Resonance (pp. 409-412). Springer Netherlands RIS download Bibtex download
  • Williamson MP () , Modern Magnetic Resonance (pp. 1357-1362). Springer Netherlands RIS download Bibtex download

Conference proceedings papers

  • Nance CL, Williamson MP, McCormick TG, Paulson SM & Shearer WT (2006) Epigallocatechin gallate, green tea catechin, binds to the T cell receptor, CD4. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol. 117(2) (pp S325-S325) RIS download Bibtex download
  • Nance CL, Williamson MP, McCormick TG & Shearer WT (2005) Binding of the green tea polyphenol, epigallocatechin gallate, to the CD4 receptor on human CD4+ T cells resulting in inhibition of HIV-1-gp120 binding. CLINICAL IMMUNOLOGY, Vol. 115 (pp S245-S246) RIS download Bibtex download
  • Miyauchi S, Nakazawa Y, Suzuki Y, Kurashina M, Sato H, Asakura T & Williamson MP (2005) Change in orientation and dynamics of DMPC molecules induced by aggregation of A尾 (1-40) molecules studied using solid state and solution NMR. Polymer Preprints, Japan, Vol. 54(2) (pp 4983) RIS download Bibtex download
  • Nakazawa Y, Suzuki Y, Miyauchi S, Sato H, Williamson MP, Ando I & Asakura T (2005) Structural and dynamical studies of A尾(1-40)-Ganglioside system with solid state and solution NMR. Polymer Preprints, Japan, Vol. 54(1) (pp 727) RIS download Bibtex download
  • Williamson MP (2003) . MAGNETIC RESONANCE IN CHEMISTRY, Vol. 41 (pp S64-S69) RIS download Bibtex download
  • Haslam E, Williamson M & Charlton A (2000) Protein-polyphenol interactions. International Congress and Symposium Series - Royal Society of Medicine(226) (pp 25-33) RIS download Bibtex download
  • Asakura T, Iwadate M, Demura M & Williamson MP (1999) Structural analysis of silk with C-13 NMR chemical shift contour plots. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, Vol. 24(2-3) (pp 167-171) RIS download Bibtex download
  • Williamson MP, Simpson PJ, Bolam DN, Hazlewood GP, Ciruela A, Cooper A & Gilbert HJ (1999) How the N-terminal xylan-binding domain from C-fimi xylanase D recognises xylan. RECENT ADVANCES IN CARBOHYDRATE BIOENGINEERING(246) (pp 212-220) RIS download Bibtex download
  • Charlton AJ, Baxter NJ, Haslam E & Williamson MP (1998) Salivary proteins as a defence against dietary tannins. COST 916 - POLYPHENOLS IN FOOD (pp 179-185) RIS download Bibtex download
  • Charlton AJ, Baxter NJ, Haslam E & Williamson MP (1998) Salivary proline-rich proteins as a defence against dietary tannins. COST 916 - POLYPHENOLS IN FOOD (pp 201-201) RIS download Bibtex download
  • PICKETT MW, WILLIAMSON MP & KELLY DJ (1994) AN ENZYME AND C-13-NMR STUDY OF CARBON METABOLISM IN HELIOBACTERIA. PHOTOSYNTHESIS RESEARCH, Vol. 41(1) (pp 75-88) RIS download Bibtex download
  • Madison VS, Fry DC, Wegrzynski BB, Williamson MP, Danho W, Heimer EP & Felix AM (1990) Derivation of solution conformers of peptide hormones via constrained molecular dynamics based on 2-D NMR data. Proceedings of the Annual Conference on Engineering in Medicine and Biology(pt 4) (pp 1612) RIS download Bibtex download

Preprints

  • Davis JL, Norwood JS, Smith RE, O鈥橠ea F, Chellappa K, Rowe ML, Williamson MP, Stafford GP, Vinogradov E, Maes E , Gu茅rardel Y et al (2024) , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Williamson M, Trevitt C, Kumar Y & Fowler N (2023) , Research Square Platform LLC. RIS download Bibtex download
  • Fowler NJ, Albalwi MF, Lee S, Hounslow AM & Williamson MP (2022) , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Fowler NJ & Williamson MP () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Fowler NJ, Sljoka A & Williamson MP () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Smith RE, Salamaga B, Szkuta P, Hajdamowicz N, Prajsnar TK, Bulmer G, Fontaine T, Ko艂odziejczyk J, Herry J-M, Hounslow A , Williamson MP et al () , Cold Spring Harbor Laboratory. RIS download Bibtex download
Research group

My laboratory uses NMR (and other methods where appropriate) to determine the structure and dynamics of proteins in solution and to study their interactions with ligands. In addition we are developing new methods for characterising structures. Further details are in my web page and in the publications list. Recent work includes:

We continue to study protein structures, particularly if this illustrates function. Recent targets include the PLAT domain of human polycystin-1, which we show to recognise phosphatidyl serine and PI4P in the membrane; the protein Mms6, which helps assemble magnetite particles in magnetotactic bacteria; and the Wbl protein (Figure), which uses an Fe-S cluster to sense NO in M. tuberculosis and hence evade host defences.

We have studied how proteins recognize polysaccharides such as starch, cellulose, xylan and peptidoglycan in bacterial cell walls: for example, the LysM module which recognises peptidoglycan and chitin, as found in bacterial and fungal cell walls and invertebrate exoskeletons.

We have been developing new tools; in particular the use of high hydrostatic pressure to stabilise partially unfolded structures, and thus investigate functional conformational change in proteins. We have started looking at Rheo-NMR, to see how proteins align and aggregate in laminar flow.

We collaborate with numerous groups. These include a logstanding collaboration with Tetsuo Asakura on silk structure; a collaboration with Jim Thomas on ruthenium-based complexes that bind B-DNA and quadruplexes; a collaboration with Robert Poole on the so-called Carbon Monoxide Releasing Molecules (CORMs); and a study on how Hofmeister ions stabilise and/or solubilise proteins.

We have a longstanding interest in polyphenols such as those from tea, and in how they interact with the body. As part of this study, we have shown that the main component of green tea, epigallocatechin gallate (EGCG), has the potential to slow down HIV infection; and that EGCG can be transported effectively by binding to albumin in the blood.

Teaching activities

Level 4 modules

  • MBB401 Introduction to research methodology
  • MBB402 Advanced literature review
  • MBB403 Extended laboratory project

Level 3 modules

  • MBB334 Biochemical Basis of Human Disease (module coordinator) - amyloid disease, obesity and inflammation
  • MBB343 Biochemical Signalling - principles, receptor tyrosine kinases, Notch and NF-kB
  • MBB361 Literature review
  • BIS303 Research project

Level 2 modules

  • BIS206 Biostructures, Energetics and Synthesis 鈥 membranes, nerve transmission and signalling
  • BIS220 Ethics and Philosophy for Molecular Biosciences

Level 1 modules

  • MBB161 Biochemistry 1 鈥 Orbitals and amino acids