New research involving the Department of Molecular Biology and Biotechnology at the University of 91直播 has revealed that genes on the genome of mealybug insects, resulting from horizontal gene transfer, have been acquired from bacterial species.
Bringing together scientists from the University of Montana, the California Institute of Technology, the National Institute of Allergy and Infectious Diseases, and the University of 91直播, this new work explored the unusual triple symbiotic relationship between mealybug insects (Planococcus citri) and two bacteria: Candidatus Tremblaya princeps, and Candidatus Moranella endobia, which reside within the cytoplasm of Tremblaya.
The study, Peptidoglycan production by an insect-bacterial mosaic, published today in Cell investigated the existence of a mosaic peptidoglycan biosynthetic pathway resulting from horizontal gene transfer, a process similar to that underpinning the function of organelles such as mitochondria and chloroplasts.
The work revealed that genes on the insect genome work together with genes on the Moranella genome to produce a component of the bacterial envelope called peptidoglycan, exclusively found at the Moranella cell periphery, a fascinating example of horizontal gene transfer, where functional bacterial genes have been acquired by insects.
Dr St茅phane Mesnage from the Department of Molecular Biology and Biotechnology said: 鈥淭his work is a perfect example of a successful multidisciplinary research involving researchers with complementary expertise.The formal identification of peptidoglycan around Moranella cells has required access to cutting-edge technologies such as NanoSIMS and high-resolution LC-MS/MS. I was delighted to contribute to this work, using the methodology we have been developing at the University of 91直播 in collaboration with Mark Collins and Adelina Acosta Martin at the biOMICS facility.鈥
