Dr Gordon Cooper

School of Biosciences

Senior University Teacher

Examinations Officer

Gordon Cooper
Profile picture of Gordon Cooper
g.j.cooper@sheffield.ac.uk
+44 114 222 4667

Full contact details

Dr Gordon Cooper
School of Biosciences
B2 222a
Alfred Denny Building
Western Bank
91Ö±²¥
S10 2TN
Profile
  • 2019 - Present: Senior University Teacher and Examination Officer, School of Biosciences, University of 91Ö±²¥
  • 2014 - 2019: Senior Lecturer and Examination Officer, Department of Biomedical Science, University of 91Ö±²¥
  • 2002-2014: Lecturer, Department of Biomedical Science, University of 91Ö±²¥
  • 2000-02: Research Associate, Department of Biomedical Science, University of 91Ö±²¥
  • 1999-00: Research Associate - School of Biological Science, University of Manchester
  • 1996-99: Postdoctoral Fellow - Dept. Cellular & Molecular Physiology, Yale University, New Haven, Ct, USA
  • 1993-96: Research Associate - Dept. Physiology, University of Leeds
  • 1990-93: Ph.D. - University of Leeds
  • 1987-90: B.Sc. Physiology (Hons) - University of Leeds
Research interests
  • Transport of gases and urea by membrane proteins
  • Function of renal potassium channels

Epithelial Transport and the movement of small solutes across biological membranes

The underlying theme to my research has been the transport of small solutes and ions across biological membranes, in particular within the kidney and other epithelia. The regulated transport of small solutes such as urea and carbon dioxide plays a critical role in whole body homeostasis.

In classifying my current research I would split it into two major themes. Firstly is the transport of water and gases across biological membranes via Aquaporins. This theme incorporates collaborations with Walter Boron (Case Western) and Gordon Cramb (St Andrews). The second theme focuses on the handling of urea by the kidney, a process critical in the ability of the body to concentrate urine. This process of renal urea handling also has implications in the regulation of blood pressure.  This theme involves collaborations with Craig Smith (Manchester) and Gavin Stewart (Dublin).

Over the last few years I have been actively involved in the redevelopment of the delivery of Physiology practical classes within the University. As part of a Physiological Society funded project I have co-ordinated the production of an online teaching resource that has facilitated the delivery of undergraduate practical sessions.

Publications

Show: Featured publications All publications

Journal articles

  • Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT & White SJ (2011) . J Physiol, 589(Pt 6), 1489-1503. RIS download Bibtex download
  • Endeward V, Musa-Aziz R, Cooper GJ, Chen LM, Pelletier MF, Virkki LV, Supuran CT, King LS, Boron WF & Gros G (2006) . FASEB Journal, 20(12), 1974-1981. RIS download Bibtex download
  • Cooper GJ & Boron WF (1998) . American Journal of Physiology-Cell Physiology, 275(6), C1481-C1486. RIS download Bibtex download

All publications

Journal articles

  • Cooper GJ, Occhipinti R & Boron WF (2015) . The Journal of Physiology, 593(23), 5033-5033. RIS download Bibtex download
  • Cooper GJ, Occhipinti R & Boron WF (2015) . The Journal of Physiology, 593(23), 5025-5028. RIS download Bibtex download
  • Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT & White SJ (2011) . J Physiol, 589(Pt 6), 1489-1503. RIS download Bibtex download
  • Laycock S, Taylor HC, Haigh C, Lee AT, Cooper GJ, Ong ACM & Robson L (2009) . Exp Physiol, 94(8), 914-927. RIS download Bibtex download
  • Stewart GS, Thistlethwaite A, Lees H, Cooper GJ & Smith C (2009) . AM J PHYSIOL-RENAL, 296(3), F642-F648. RIS download Bibtex download
  • Millar ID, Taylor HC, Cooper GJ, Kibble JD, Barhanin J & Robson L (2006) . Pflugers Arch, 453(1), 107-116. RIS download Bibtex download
  • Stewart GS, Smith CP & Cooper GJ (2006) . AM J PHYSIOL-RENAL, 290(6), F1437-F1442. RIS download Bibtex download
  • Endeward V, Musa-Aziz R, Cooper GJ, Chen LM, Pelletier MF, Virkki LV, Supuran CT, King LS, Boron WF & Gros G (2006) . FASEB Journal, 20(12), 1974-1981. RIS download Bibtex download
  • Millar ID, Taylor HC, Cooper GJ, Kibble JD & Robson L (2006) . J Membr Biol, 211(3), 173-184. RIS download Bibtex download
  • Fowler MR, Cooper GJ & Hunter M (2004) . AM J PHYSIOL-RENAL, 286(6), F1219-F1225. RIS download Bibtex download
  • Stewart GS, Fenton RA, Wang W, Kwon T-H, White SJ, Collins VM, Cooper G, Nielsen S & Smith CP (2004) . American Journal of Physiology-Renal Physiology, 286(5), F979-F987. RIS download Bibtex download
  • Cooper GJ & Fong P (2003) . Am J Physiol Cell Physiol, 284(2), C331-C338. RIS download Bibtex download
  • Fenton RA, Stewart GS, Carpenter B, Howorth A, Potter EA, Cooper GJ & Smith CP (2002) . AM J PHYSIOL-RENAL, 283(4), F817-F825. RIS download Bibtex download
  • Collins VM, Cooper GJ & White SJ (2002) Functional implications of an N-terminus truncation on rat ROMK2.. J AM SOC NEPHROL, 13, 71A-71A. RIS download Bibtex download
  • Fenton RA, Cooper GJ, Morris ID & Smith CP (2002) . American Journal of Physiology-Cell Physiology, 282(6), C1492-C1501. RIS download Bibtex download
  • Cooper GJ, Hill C & White SJ (2002) Effects of the Bartter's syndrome mutation M357T on ROMK2. J PHYSIOL-LONDON, 539, 3P-3P. RIS download Bibtex download
  • Park K, Hurley PT, Roussa E, Cooper GJ, Smith CP, Thévenod F, Steward MC & Case RM (2002) . Archives of Oral Biology, 47(1), 1-9. RIS download Bibtex download
  • Cooper GJ, Zhou Y, Bouyer P, Grichtchenko II & Boron WF (2002) . Journal of Physiology, 542(1), 17-29. RIS download Bibtex download
  • Virkki LV, Cooper GJ & Boron WF (2001) . American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 281(6), R1994-R2003. RIS download Bibtex download
  • Davis BA, Hogan EM, Cooper GJ, Bashi E, Zhao J & Boron WF (2001) . Journal of Membrane Biology, 183(1), 25-32. RIS download Bibtex download
  • Cooper GJ, Fowler M & Hunter M (2001) . Pflugers Arch, 442(2), 243-247. RIS download Bibtex download
  • Fenton RA, Howorth A, Cooper GJ, Meccariello R, Morris ID & Smith CP (2000) . American Journal of Physiology-Cell Physiology, 279(5), C1425-C1431. RIS download Bibtex download
  • Leipziger J, MacGregor GG, Cooper GJ, Xu J, Hebert SC & Giebisch G (2000) . American Journal of Physiology-Renal Physiology, 279(5), F919-F926. RIS download Bibtex download
  • Walsh PJ, Heitz MJ, Campbell CE, Cooper GJ, Medina M, Wang YS, Goss GG, Vincek V, Wood CM & Smith CP (2000) Molecular characterization of a urea transporter in the gill of the gulf toadfish (Opsanus beta). Journal of Experimental Biology, 203(15), 2357-2364. RIS download Bibtex download
  • Cooper GJ & Boron WF (1998) . American Journal of Physiology-Cell Physiology, 275(6), C1481-C1486. RIS download Bibtex download
  • Cooper GJ & Hunter M (1997) . The Journal of Physiology, 498(1), 49-59. RIS download Bibtex download
  • Cooper GJ & Hunter M (1996) . The Journal of Physiology, 491(1), 219-223. RIS download Bibtex download
  • Cooper GJ & Hunter M (1994) . The Journal of Physiology, 479(3), 423-432. RIS download Bibtex download
  • Cooper G, Hurst A, Lynch P & Hunter M (1994) . Kidney and Blood Pressure Research, 17(3-4), 138-142. RIS download Bibtex download
  • COOPER GJ & KOHN PG (1980) ALPHA-AMINOISOBUTYRIC-ACID TRANSPORT IN RAT SOLEUS MUSCLE AND ITS MODIFICATION BY MEMBRANE STABILIZERS AND INSULIN. J PHYSIOL-LONDON, 302(MAY), 89-105. RIS download Bibtex download
  • Cooper G (1979) . American Journal of Physiology-Heart and Circulatory Physiology, 236(2), H244-H253. RIS download Bibtex download
  • COOPER GJ & KOHN PG (1977) MECHANISM OF 2-AMINO-ISO-BUTYRIC ACID EFFLUX FROM RAT SOLEUS MUSCLE AND ITS MODIFICATION BY MEMBRANE STABILIZER, TETRACAINE. J PHYSIOL-LONDON, 271(2), P20-P20. RIS download Bibtex download
  • COOPER GJ & KOHN PG (1973) EFFECT OF TETRACAINE ON 2-AMINOISOBUTYRIC ACID TRANSPORT IN MUSCLE. J PHYSIOL-LONDON, 229(1), P23-&. RIS download Bibtex download

Conference proceedings papers

  • Collins VM, Cooper GJ & White SJ (2006) Apical membrane targeting of ROMK2 is independent of N-linked glycosylation. FASEB JOURNAL, Vol. 20(4) (pp A328-A328) RIS download Bibtex download
  • White SJ, Cooper GJ, Hajihashemi S, Ware TL & Murray LA (2003) Cloning and functional expression of zebrafish (Danio rerio) ROMK2 (Kir1.1 b).. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 79A-79A) RIS download Bibtex download
  • Cooper GJ (2003) The functional unit of a frog urea transporter (fUT) is multimeric.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 75A-75A) RIS download Bibtex download
  • White SJ, Hajihasemi S, Cooper GJ, Robson L & Ortega B (2003) A C-terminal mutation enhances ROMK2 stability in oocytes and MDCK cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 78A-78A) RIS download Bibtex download
  • Collins VM, Cooper GJ & White SJ (2002) The N terminus of ROMK2 is necessary for channel function but not membrane trafficking. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 544 (pp 8P-8P) RIS download Bibtex download
  • Cooper GJ & Hunter M (1993) Alteration of Na+-H+ exchanger setpoint by furosemide (frusemide) in frog isolated early distal tubule (EDT). Journal of Physiology, Vol. 467 RIS download Bibtex download
  • Cooper G, Stone V & Hunter M (1992) Furosemide induces cytoplasmic alkalinization in frog early distal tubules. Journal of Physiology, Vol. 446 RIS download Bibtex download
Grants
  • The Physiological Society - David Jordan Teaching Grant
  • NERC
  • Kidney Research UK.
Teaching activities

Undergraduate and postgraduate taught modules

Undergraduate:

  • BMS109-108 Physiology with Pharmacology
  • BMS109 Lab Skills & Skills Sessions
  • BMS109 Introduction to Organ Systems
  • BMS221 Physiology at the Extreme
  • BMS242/43 Career Development Skills (Coordinator)
  • BMS242/243 Core Phys Pharm
  • BMS242, 244 CVS Respiratory
  • BMS311 The Kidney in Health & Disease
  • BMS346 Epithelial Physiology in Health and Disease
  • BMS316 Group Research Initiatives (Coordinator)
  • Level 3 Practical and Dissertation Modules

Masters (MSc):

  • BMS6063 Epithelial Physiology in Health and Disease
Professional activities and memberships
  • Fellow of the Physiological Society
  • Senior Fellow of the Higher Education Academy (SFHEA)
  • Invited Speaking. September 2013 - Invited speaker at Symposium on Mammalian Urea Transporters held at University College in Dublin.