Shaw, Pamela J, Professor Dame

Professor Dame Pamela J Shaw

DBE, MBBS, MD, FRCP, FMedSci, FAAN, FANA, FAAAS

Neuroscience, School of Medicine and Population Health

Director of the 91ֱ�� Institute for Translational Neuroscience (SITraN)

Professor of Neurology

Director, NIHR Biomedical Research Centre Translational Neuroscience for Chronic Neurological Disorders

Director, 91ֱ�� Care and Research Centre for Motor Neuron Disorders

Director, Cross-Faculty Flagship Neuroscience Institute

Honorary Consultant Neurologist, 91ֱ�� Teaching Hospitals NHS Foundation Trust

pamela.shaw@sheffield.ac.uk
+44 114 222 2295

+44 114 226 1049 (Medical NHS Secretary: Helen Rains)

+44 114 222 2295 (Academic Administrator: Gillian Griffiths)

91ֱ�� Institute for Translational Neuroscience (SITraN)

Full contact details

Professor Dame Pamela J Shaw
Neuroscience, School of Medicine and Population Health
91ֱ�� Institute for Translational Neuroscience (SITraN)
385a Glossop Road
91ֱ��
S10 2HQ

Profile

Pamela Shaw is an academic neurologist and a world-leading researcher in motor neuron disease (MND). She has held extensive leadership roles at local/national/international levels including: Director-91ֱ�� Institute for Translational Neuroscience (SITraN) (2010-present); Director University of 91ֱ�� Cross-Faculty Neuroscience Institute (2019-present); Pro-Vice Chancellor Faculty of Health (2016-2019). NIHR leadership roles include DeNDRoN Associate Director (2006-15);Yorkshire&Humber CRN Division 4 Lead (2014-16);Director-91ֱ�� NIHR BRC (2017-present). Nationally she led the Association of British Neurologists (ABN) Clinical Research Academic Committee and served as panel member for MRC, Wellcome, Academy Medical Sciences, UKRI, Lister Institute, NIHR Senior Investigator awards. Internationally she is a founding/executive member of ENCALS and chaired the International Scientific Programme Committee for ALS/MND (2004-10).

She has systematically built scientific and clinical facilities and diverse, multidisciplinary teams to deliver effective translational research for neurodegeneration. She uses genetics and biological studies in pre-clinical model systems linked to human biosamples, to define novel pathways of disease, and to identify promising small molecule and gene-therapy targets, together with novel biomarkers.

Significant contributions from MND clinical research include: identification and introduction into clinical practice of riluzole; evaluation of further potential neuroprotective therapies in >22 clinical trials; demonstration that support with non-invasive ventilation (NIV) has a major positive impact on QOL and survival which changed management internationally. She has contributed significantly to the genetic subclassification of MND including identification of changes in CHMP2B;TARDB;FUS;C9ORF72;TUBA4A;NEK1;Annexin A11;GLT8D1 genes, together with the associated clinical phenotype and molecular pathology. She has also demonstrated the value of offering routine genetic screening for MND patients.

Her team has generated a translational pipeline of potential neuroprotective therapies. Using viral vectors (AAV9) to deliver neuroprotective cargoes to the CNS, she has demonstrated dramatic therapeutic effects in pre-clinical models of SOD1-MND and SMA. This work has underpinned successful experimental medicine trials. Transcriptomic work has identified several pathways which can be modified therapeutically including the NRF2-anti-oxidant response and SRSF1, which are currently being developed towards MND clinical trials.

She has authored >560 publications (H-index 116, Citations 48,225) and secured >£140m in research funding. She has supervised and mentored the career development of >190 young scientists and clinicians, including 55 PhD students. She has delivered >600 presentations at national/international venues including many plenary/keynote invited lectures.

Multiple awards recognising her translational research contributions include: NIHR Senior Investigator Award-2013-2021; DBE for Services to Neuroscience-2014; American Academy of Neurology Sheila Essey Award-2001;International ALS/MND Alliance Forbes Norris Award-2007;Royal College of Physicians Jean Hunter Award-2006/Croonian Lecture-2016; FMedSci-2007; Fellowship American Association for the Advancement of Science-2015;ABN Medallist-2019; Queen’s Anniversary Award to SITraN-2019; Singhal Award Lecture World Congress of Neurology 2021; Platinum Clinical Excellence Award-2013-present; British Neuroscience Research Excellence award 2022.

She has supported academic capacity development locally, building a department of >300 staff and graduate students since 2000 and nationally through DeNDroN and the ABN. She has mentored future research leaders through the NIHR Academy and the Academy of Medical Sciences. As Pro-VC she led the Medical School Athena Swan Silver award and promoted the Faculty Equality-Diversity-Inclusion agenda appointing a Faculty EDI Director and introducing mandatory EDI staff training.

Professor Shaw graduated in Medicine with 1st Class Honours from the University of Newcastle in 1979. She undertook her MRCP and Specialist Training in Neurology in Newcastle.

In 1988 she was awarded an MD with commendation for her work on the neurological complications of coronary bypass surgery. After an intermediate fellowship award from the Wellcome Trust, she was awarded a Wellcome Senior Fellowship in Clinical Science which she held from 1991 -2001.

In 1997 she was appointed Professor of Neurological Medicine at the University of Newcastle and in 2000 was appointed as Professor of Neurology at the University of 91ֱ��.

As an undergraduate in Newcastle she was awarded the Stephen Scott; Gibb; Mary Gordon; Mona McNaughton and Phillipson Prizes/Scholarships and achieved distinction in all undergraduate examinations.

Research interests

Professor Shaw is a Clinician Scientist in Neurology, an emeritus NIHR Senior Investigator and formerly a Wellcome Senior Clinical Fellow. Supported by long-term programme funding from the Wellcome Trust, she has since 1991 led a major multidisciplinary programme of research investigating genetic, molecular and neurochemical factors underlying neurodegenerative disorders of the human motor system.

Her team use robust cellular and in vivo models of neurodegeneration and correlate key findings with disease related changes in the human nervous system. Significant research achievements include:

Identification of cell specific features of motor neurons which underlie susceptibility to neurodegeneration.
Understanding the cellular pathways of motor neuron injury in the presence of mutant SOD1 using a combination of cell biology, proteomics and gene expression profiling.
Subclassification of motor neuron disease (MND) based on genetics and molecular pathology.
Development of new small molecule and gene therapy candidate treatments for patients using staged screening programmes in cellular and other experimental model systems linked to human biosamples.
Promoting the introduction of neuroprotective treatments for MND into trials and clinical practice e.g. riluzole, tofersen, aldesleukin.
Establishing the role of non-invasive ventilation (NIV) in improving the quality of life and prolonging survival of MND patients.

Professor Shaw’s research is currently funded by the Medical Research Council, NIHR, LifeArc, the Motor Neurone Disease Association, the My Name’5 Doddie Foundation, Fight MND, the US Department of Defence, the European Union and biotechnology & pharmaceutical industry partners.

Current projects

Professor Shaw’s research is focused on 3 main goals:

To understand the function of motor neurons in health and disease and to translate basic science findings into health benefits for patients with degenerative motor system disorders.
To provide excellent clinical care for patients with motor system disorders, at all disease stages incorporating: multidisciplinary team working, evidence based standards of care for symptomatic management, and evaluation of new neuroprotective therapies.
To foster excellent training for clinical and scientific junior staff with the aim of ensuring high standards of future care and linking new developments in medical science firmly to the needs of patients with neurological disorders.

Since 1983 she has supervised the research training of > 190 individuals from medicine and science including 55 PhD/MD students.

Professor Shaw is the Director of the NIHR 91ֱ�� Biomedical Research Centre translating new potential treatments from SITraN research into early phase and experimental medicine clinical trials

Publications

Journal articles

Qiang Z, Barnett L, Bingham G, Han O, Walsh A, Conwill M, McDonough HE, McDermott CJ, Shaw PJ & Alix JJP (2025) . Journal of Neurology, 272(1).
Webster CP, Hall B, Crossley OM, Dauletalina D, King M, Lin Y-H, Castelli LM, Yang Z-L, Coldicott I, Kyrgiou-Balli E , Higginbottom A et al (2025) . Life Science Alliance, 8(2), e202402757-e202402757.
Harvey C, Nowak A, Zhang S, Moll T, Weimer AK, Barcons AM, Souza CDS, Ferraiuolo L, Kenna K, Zaitlen N , Caggiano C et al (2024) .
Rawlinson C, Gould RL, McDermott CJ, Thompson B, Weeks K, Gossage-Worrall R, Serfaty MA, Graham CD, McCracken L, White D , Howard RJ et al (2024) . The Cognitive Behaviour Therapist, 17.
Saez-Atienzar S, Souza CDS, Chia R, Beal SN, Lorenzini I, Huang R, Levy J, Burciu C, Ding J, Gibbs JR , Jones A et al (2024) . Cell Genomics, 100679-100679.
Burrows DJ, McGown A, Abduljabbar O, Castelli LM, Shaw PJ, Hautbergue GM & Ramesh TM (2024) . Annals of Neurology.
van den Berg LH, Rothstein JD, Shaw PJ, Babu S, Benatar M, Bucelli RC, Genge A, Glass JD, Hardiman O, Libri V , Mobach T et al (2024) . The Lancet Neurology.
Vrellaku B, Hassan IS, Howitt R, Webster CP, Harriss E, McBlane F, Betts C, Schettini J, Lion M, Mindur JE , Duerr M et al (2024) . Molecular Therapy.
Shaw PJ & Cooper-Knock J (2024) . Neurology, 103(2).
Au WH, Miller-Fleming L, Sanchez-Martinez A, Lee JAK, Twyning MJ, Prag HA, Raik L, Allen SP, Shaw PJ, Ferraiuolo L , Mortiboys H et al (2024) . Life Science Alliance, 7(9), e202402853-e202402853.
Marriott H, Spargo TP, Al Khleifat A, Andersen PM, Başak NA, Cooper‐Knock J, Corcia P, Couratier P, de Carvalho M, Drory V , Gotkine M et al (2024) . Annals of Clinical and Translational Neurology.
Taş G, Westerdijk T, Postma E, van Rheenen W, Bakker MK, van Eijk KR, Kooyman M, Al Khleifat A, Iacoangeli A, Ticozzi N , Cooper-Knock J et al (2024) . Bioinformatics, 40(6).
Alarcan H, Bruno C, Emond P, Raoul C, Vourc'h P, Corcia P, Camu W, Veyrune J, Garlanda C, Locati M , Juntas‐Morales R et al (2024) . Annals of the New York Academy of Sciences.
Gould RL, McDermott CJ, Thompson BJ, Rawlinson CV, Bursnall M, Bradburn M, Kumar P, Turton EJ, White DA, Serfaty MA , Graham CD et al (2024) . The Lancet.
Aragón-González A, Shaw AC, Kok JR, Roussel FS, Santos Souza CD, Granger SM, Vetter T, de Diego Y, Meyer KC, Beal SN , Shaw PJ et al (2024) . Fluids and Barriers of the CNS, 21(1).
Conwill MT, Alix JJP & Shaw PJ (2024) . Muscle & Nerve, 69(6), 733-734.
Alix JJP, Plesia M, Dudgeon AP, Kendall CA, Hewamadduma C, Hadjivassiliou M, Gorman GS, Taylor RW, McDermott CJ, Shaw PJ , Mead RJ et al (2024) . The Analyst.
Harvey C, Weinreich M, Lee JAK, Shaw AC, Ferraiuolo L, Mortiboys H, Zhang S, Hop PJ, Zwamborn RAJ, van Eijk K , Julian TH et al (2024) . Heliyon, 10(3), e24975-e24975.
Evans LJ, O’Brien D & Shaw PJ (2024) .
Bell SM, Wareing H, Hamshaw A, De S, New E, Shaw P, De Marco M, Venneri A, Blackburn DJ, Ferraiuolo L & Mortiboys H (2023) . Alzheimer's & Dementia, 19(S13).
Lombardo FL, Spila Alegiani S, Mayer F, Cipriani M, Lo Giudice M, Ludolph AC, McDermott CJ, Corcia P, Van Damme P, Van den Berg LH , Hardiman O et al (2023) . Trials, 24(1).
Richardson PJ, Smith DP, de Giorgio A, Snetkov X, Almond-Thynne J, Cronin S, Mead RJ, McDermott CJ & Shaw PJ (2023) . Translational Neurodegeneration, 12(1).
Gould RL, Rawlinson C, Thompson B, Weeks K, Gossage-Worrall R, Cantrill H, Serfaty MA, Graham CD, McCracken LM, White D , Howard RJ et al (2023) . Pilot and Feasibility Studies, 9.
Chen Z, Reynolds RH, Pardiñas AF, Gagliano Taliun SA, van Rheenen W, Lin K, Shatunov A, Gustavsson EK, Fogh I, Jones AR , Robberecht W et al (2023) . Neurobiology of Disease, 180, 106082-106082.
Adey BN, Cooper-Knock J, Al Khleifat A, Fogh I, van Damme P, Corcia P, Couratier P, Hardiman O, McLaughlin R, Gotkine M , Drory V et al (2023) . Frontiers in Cellular Neuroscience, 17.
Castelli LM, Lin Y-H, Sanchez-Martinez A, Gül A, Mohd Imran K, Higginbottom A, Upadhyay SK, Márkus NM, Rua Martins R, Cooper-Knock J , Montmasson C et al (2023) . Science Translational Medicine, 15(685).
Gandhi R, Selvarajah D, Sloan G, Greig M, Wilkinson ID, Shaw PJ, Griffiths P & Tesfaye S (2023) . Frontiers in Pain Research, 3.
Yildiz O, Schroth J, Tree T, Turner MR, Shaw PJ, Henson SM & Malaspina A (2023) . Neurology - Neuroimmunology Neuroinflammation, 10(1), e200042-e200042.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, dos Santos Souza C, Zhang S , Castelli L et al (2023) . Life Science Alliance, 6(1), e202201449-e202201449.
Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin Y-H, Smith EF, Illanes-Álvarez F, Higginbottom A, Shaw PJ , Azzouz M et al (2022) . Frontiers in Cellular Neuroscience, 16.
Al Khleifat A, Iacoangeli A, Jones AR, van Vugt JJFA, Moisse M, Shatunov A, Zwamborn RAJ, van der Spek RAA, Cooper-Knock J, Topp S , van Rheenen W et al (2022) . Frontiers in Cellular Neuroscience, 16.
Aragón-González A, Shaw PJ & Ferraiuolo L (2022) . International Journal of Molecular Sciences, 23(23).
Opie-Martin S, Iacoangeli A, Topp SD, Abel O, Mayl K, Mehta PR, Shatunov A, Fogh I, Bowles H, Limbachiya N , Spargo TP et al (2022) . Nature Communications, 13(1).
Mehta PR, Iacoangeli A, Opie-Martin S, van Vugt JJFA, Al Khleifat A, Bredin A, Ossher L, Andersen PM, Hardiman O, Mehta AR , Fratta P et al (2022) . Brain, 145(12), 4440-4447.
Miller TM, Cudkowicz ME, Genge A, Shaw PJ, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD , Andrews JA et al (2022) . New England Journal of Medicine, 387(12), 1099-1110.
Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ & Sobue G (2022) . The Lancet.
Sassani M, Alix J, Baster K, Cercignani M, Shaw P & Jenkins T (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(9), e2.136-e2.136.
Chapman L, Shepheard S, Verber N, Turner M, Malaspina A, Rogers M-L & Shaw P (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(9), e2.130-e2.130.
Shaw P, Miller T, Cudkowicz M, Genge A, Sobue G, Nestorov I, Graham D-I, Fanning L, Fradette S & McNeill M (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(9), e2.208-e2.208.
Dennys C, Baggio C, Rodrigo R, Roussel F, Kulinich A, Heintzman S, Fox A, Kolb SJ, Shaw PJ, Ethell IM , Pellecchia M et al (2022) . iScience, 104877-104877.
Cooper‐Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T , Shelkovnikova T et al (2022) . Brain Pathology.
Alix JJP, Plesia M, Hool SA, Coldicott I, Kendall CA, Shaw PJ, Mead RJ & Day JC (2022) . Muscle and Nerve.
Franklin J, Cooper-Knock J, Baheerathan A, Moll T, Heverin M, Hardiman O, Mannikko R, Shaw P & Hanna M (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(6), A13.2-A13.
Price K, Mellor J, Mcnamara M, Hewamadduma C, Shaw P, Derott CM & Hadjivassiliou M (2022) . Journal of Neurology, Neurosurgery & Psychiatry, 93(6), A10.1-A10.
Schooling CN, Healey TJ, McDonough HE, French SJ, McDermott CJ, Shaw PJ, Kadirkamanathan V & Alix JJP (2022) . Clinical Neurophysiology, 139, 69-75.
Alix J, Plesia M, Lloyd GR, Dudgeon A, Kendall CA, Hewamadduma C, Hadjivassiliou M, McDermott C, Gorman G, Taylor R , Shaw PJ et al (2022) . Analyst.
Marrone L, Marchi PM, Webster CP, Marroccella R, Coldicott I, Reynolds S, Alves-Cruzeiro J, Yang Z-L, Higginbottom A, Khundadze M , Shaw PJ et al (2022) . Human Molecular Genetics.
Gomes C, Sequeira C, Likhite S, Dennys CN, Kolb SJ, Shaw PJ, Vaz AR, Kaspar BK, Meyer K & Brites D (2022) . Cells, 11(7).
Eitan C, Siany A, Barkan E, Olender T, van Eijk KR, Moisse M, Farhan SMK, Danino YM, Yanowski E, Marmor-Kollet H , Rivkin N et al (2022) . Nature Neuroscience, 25(4), 433-445.
Boddy S, Islam M, Moll T, Kurz J, Burrows D, McGown A, Bhargava A, Julian TH, Harvey C, Marshall JNG , Hall BPC et al (2022) . Brain Communications, 4(2).
Hop PJ, Zwamborn RAJ, Hannon E, Shireby GL, Nabais MF, Walker EM, van Rheenen W, van Vugt JJFA, Dekker AM, Westeneng H-J , Tazelaar GHP et al (2022) . Science Translational Medicine, 14(633).
Thompson AG, Gray E, Verber N, Bobeva Y, Lombardi V, Shepheard SR, Yildiz O, Feneberg E, Farrimond L, Dharmadasa T , Gray P et al (2022) . Brain Communications, 4(1).
van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra H-J, Bakker OB, Deelen P , Shireby G et al (2022) . Nature Genetics, 54(3), 361-361.
Al Khleifat A, Iacoangeli A, van Vugt JJFA, Bowles H, Moisse M, Zwamborn RAJ, van der Spek RAA, Shatunov A, Cooper-Knock J, Topp S , Byrne R et al (2022) . npj Genomic Medicine, 7(1).
Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Marshall JNG, Harvey C, Nezhad HG, Franklin J, Souza CDS , Ning K et al (2022) . Neuron.
Škorić-Milosavljević D, Tadros R, Bosada FM, Tessadori F, van Weerd JH, Woudstra OI, Tjong FVY, Lahrouchi N, Bajolle F, Cordell HJ , Agopian AJ et al (2022) . Circulation Research, 130(2), 166-180.
Julian TH, Boddy S, Islam M, Kurz J, Whittaker KJ, Moll T, Harvey C, Zhang S, Snyder MP, McDermott C , Cooper-Knock J et al (2022) . Brain, 145(3), 832-842.
Alix JJP, Plesia M, Lloyd GR, Dudgeon AP, Kendall CA, McDermott CJ, Gorman GS, Taylor RW, Shaw PJ & Day JC (2022) . Journal of Raman Spectroscopy, 53(2), 172-181.
Chan Y, Alix JJP, Neuwirth C, Barkhaus PE, Castro Tech J, Jenkins TM, McDermott CJ, Shaw PJ, Carvalho M, Nandedkar S , Stålberg E et al (2022) . Muscle & Nerve, 65(2), 203-210.
Anton A, Mead RJ, Shaw PJ, Edden RAE, Bigley J, Jenkins TM, Wild JM, Hoggard N & Wilkinson ID (2022) . Journal of Magnetic Resonance Imaging, 55(2), 435-442.
Benson BC, Shaw PJ, Azzouz M, Highley JR & Hautbergue GM (2021) . Frontiers in Neuroscience, 15.
Moll T, Marshall JNG, Soni N, Zhang S, Cooper-Knock J & Shaw PJ (2021) . Essays in Biochemistry, 65(7), 999-1011.
van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra H-J, Bakker OB, Deelen P , Shireby G et al (2021) . Nature Genetics, 53(12), 1636-1648.
Schooling CN, Healey TJ, McDonough HE, French SJ, McDermott CJ, Shaw PJ, Kadirkamanathan V & Alix JJP (2021) . Physiological Measurement, 42(10).
Johnson JO, Chia R, Miller DE, Li R, Kumaran R, Abramzon Y, Alahmady N, Renton AE, Topp SD, Gibbs JR , Cookson MR et al (2021) . JAMA Neurology, 78(10), 1236-1248.
Shaw P (2021) . Journal of the Neurological Sciences, 429, 117636-117636.
Sassani M, Alix J, Mcdermott C, Baster K, Hoggard N, Wild J, Mortiboys H, Shaw P, Wilkinson I & Jenkins T (2021) . Journal of the Neurological Sciences, 429, 119412-119412.
van Eijk RPA, Nikolakopoulos S, Roes KCB, Kendall L, Han SS, Lavrov A, Epstein N, Kliest T, de Jongh AD, Westeneng H-J , Al-Chalabi A et al (2021) . Neurology, 97(11), 528-536.
Gerou M, Hall B, Woof R, Allsop J, Kolb SJ, Meyer K, Shaw PJ & Allen SP (2021) . Neurobiology of Aging, 105, 64-77.
Jiménez-Villegas J, Ferraiuolo L, Mead RJ, Shaw PJ, Cuadrado A & Rojo AI (2021) . Free Radical Biology and Medicine, 173, 125-141.
Watkins JA, Alix JJP, Shaw PJ & Mead RJ (2021) . Scientific Reports, 11(1).
Giovannelli I, Bayatti N, Brown A, Wang D, Mickunas M, Camu W, Veyrune J-L, Payan C, Garlanda C, Locati M , Juntas-Morales R et al (2021) . Brain Communications, 3(3).
Castelli LM, Cutillo L, Souza CDS, Sanchez-Martinez A, Granata I, Lin Y-H, Myszczynska MA, Heath PR, Livesey MR, Ning K , Azzouz M et al (2021) . Molecular Neurodegeneration, 16(1).
Dajti I, Valenzuela JI, Boccalatte LA, Gemelli NA, Smith DE, Dudi-Venkata NN, Kroon HM, Sammour T, Roberts M, Mitchell D , Lah K et al (2021) . British Journal of Surgery, 108(11), 1274-1292.
Ciervo Y, Gatto N, Allen C, Grierson A, Ferraiuolo L, Mead RJ & Shaw PJ (2021) . Molecular Therapy — Methods & Clinical Development, 21, 413-433.
Pham TK, Buczek WA, Mead RJ, Shaw PJ & Collins MO (2021) . Frontiers in Molecular Neuroscience, 14.
Julian TH, Glascow N, Barry ADF, Moll T, Harvey C, Klimentidis YC, Newell M, Zhang S, Snyder MP, Cooper-Knock J & Shaw PJ (2021) . EBioMedicine, 68.
Plesia M, Stevens OA, Lloyd GR, Kendall CA, Coldicott I, Kennerley AJ, Miller G, Shaw PJ, Mead RJ, Day JCC & Alix JJP (2021) . ACS Chemical Neuroscience, 12(10), 1768-1776.
Nabais MF, Laws SM, Lin T, Vallerga CL, Armstrong NJ, Blair IP, Kwok JB, Mather KA, Mellick GD, Sachdev PS , Wallace L et al (2021) . Genome Biology, 22.
Shepheard SR, Parker MD, Cooper-Knock J, Verber NS, Tuddenham L, Heath P, Beauchamp N, Place E, Sollars ESA, Turner MR , Malaspina A et al (2021) . Journal of Neurology, Neurosurgery & Psychiatry, 92(5), 510-518.
Appleby‐Mallinder C, Schaber E, Kirby J, Shaw PJ, Cooper‐Knock J, Heath PR & Highley JR (2021) . Neuropathology and Applied Neurobiology, 47(1), 61-72.
Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C , Hornstein E et al (2021) . Cell Reports, 34(5), 108730-108730.
Boddy SL, Giovannelli I, Sassani M, Cooper-Knock J, Snyder MP, Segal E, Elinav E, Barker LA, Shaw PJ & McDermott CJ (2021) . BMC Medicine, 19(1).
Gatto N, Dos Santos Souza C, Shaw AC, Bell SM, Myszczynska MA, Powers S, Meyer K, Castelli LM, Karyka E, Mortiboys H , Azzouz M et al (2021) . Aging Cell, 20(1).
Moisse M, Zwamborn RAJ, Vugt J, Spek R, Rheenen W, Kenna B, Van Eijk K, Kenna K, Corcia P, Couratier P , Vourc'h P et al (2021) . Annals of Neurology, 89(4), 686-697.
Sassani M, Alix J, McDermott C, Baster K, Hoggard N, Wild J, Mortiboys H, Shaw P, Wilkinson I & Jenkins T (2021) . Brain, 143(12), 3603-3618.
Bell SM, Barnes K, De Marco M, Shaw PJ, Ferraiuolo L, Blackburn DJ, Venneri A & Mortiboys H (2021) . Biomedicines, 9(1).
Bury JJ, Chambers A, Heath PR, Ince PG, Shaw PJ, Matthews FE, Brayne C, Simpson JE & Wharton SB (2021) . Acta Neuropathologica Communications, 9(1).
Dewan R, Chia R, Ding J, Hickman RA, Stein TD, Abramzon Y, Ahmed S, Sabir MS, Portley MK, Tucci A , Ibáñez K et al (2021) . Neuron, 109(3), 448-460.e4.
Hop PJ, Zwamborn RAJ, Hannon EJ, Dekker AM, van Eijk KR, Walker EM, Iacoangeli A, Jones AR, Shatunov A, Khleifat AA , Opie-Martin S et al (2020) . NAR Genomics and Bioinformatics, 2(4).
Ghahremani Nezhad H, Franklin JP, Alix JJP, Moll T, Pattrick M, Cooper-Knock J, Shanmugarajah P, Beauchamp NJ, Hadjivissiliou M, Paling D , Mcdermott C et al (2020) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(7-8), 579-582.
Schooling CN, Jamie Healey T, McDonough HE, French SJ, McDermott CJ, Shaw PJ, Kadirkamanathan V & Alix JJP (2020) . Physiological Measurement, 41(12).
Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C , Hornstein E et al (2020) . Cell Reports, 33(9), ---.
Franklin JP, Azzouz M & Shaw PJ (2020) . Expert Opinion on Orphan Drugs, 8(10), 379-392.
Verber N & Shaw PJ (2020) . Current Opinion in Neurology, 33(5), 662-668.
Crooks L, Cooper-Knock J, Heath PR, Bouhouche A, Elfahime M, Azzouz M, Bakri Y, Adnaoui M, Ibrahimi A, Amzazi S & Tazi-Ahnini R (2020) . BMC Genetics, 21(1).
Sproson L, Lanfranchi V, Collins A, Chhetri SK, Daly N, Ennis M, Glennon L, Gorrie G, Jay E, Marsden R , McCarthy AD et al (2020) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(1-2), 38-45.
Chambers A, Bury JJ, Minett T, Richardson CD, Brayne C, Ince PG, Shaw PJ, Garwood CJ, Heath PR, Simpson JE , Matthews FE et al (2020) . Journal of Neuropathology & Experimental Neurology, 79(9), 950-958.
Camu W, Mickunas M, Veyrune J-L, Payan C, Garlanda C, Locati M, Juntas-Morales R, Pageot N, Malaspina A, Andreasson U , Kirby J et al (2020) . EBioMedicine, 59.
Lahrouchi N, Tadros R, Crotti L, Mizusawa Y, Postema PG, Beekman L, Walsh R, Hasegawa K, Barc J, Ernsting M , Turkowski KL et al (2020) . Circulation, 142(4), 324-338.
Miller T, Cudkowicz M, Shaw PJ, Andersen PM, Atassi N, Bucelli RC, Genge A, Glass J, Ladha S, Ludolph AL , Maragakis NJ et al (2020) . New England Journal of Medicine, 383(2), 109-119.
Franklin JP, Cooper-Knock J, Baheerathan A, Moll T, Männikkö R, Heverin M, Hardiman O, Shaw PJ & Hanna MG (2020) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(7-8), 627-630.
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Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A & Wharton SB (2015) . Neuropathology and Applied Neurobiology, 41(4), 483-496.
Cooper-Knock J, Bury JJ, Heath PR, Wyles M, Higginbottom A, Gelsthorpe C, Highley JR, Hautbergue G, Rattray M, Kirby J & Shaw PJ (2015) . PLOS ONE, 10(5), e0127376-e0127376.
Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ & Azzouz M (2015) . Expert Opinion on Biological Therapy, 15(7), 935-947.
Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE , Shaw PJ et al (2015) . Neurobiology of Aging, 36(5), 2006.e1-2006.e9.
Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang L, Liu T, Lassen CF, Meissner E , Alexopoulos P et al (2015) . Alzheimer's & Dementia, 11(12), 1407-1416.
Nicholls Z, Hobson E, Martindale J & Shaw PJ (2015) . Practical Neurology, 15(4), 280-283.
Cooper-Knock J, Kirby J, Highley R & Shaw PJ (2015) . Neurotherapeutics, 12(2), 326-339.
Cirulli ET, Lasseigne BN, Petrovski S, Sapp PC, Dion PA, Leblond CS, Couthouis J, Lu Y-F, Wang Q, Krueger BJ , Ren Z et al (2015) . Science, 347(6229), 1436-1441.
Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE & Wharton SB (2015) . PLoS One, 10(2).
Walsh MJ, Cooper-Knock J, Dodd JE, Stopford MJ, Mihaylov SR, Kirby J, Shaw PJ & Hautbergue GM (2015) . Neuropathology and Applied Neurobiology, 41(2), 109-134.
Little D, Valori CF, Mutsaers CA, Bennett EJ, Wyles M, Sharrack B, Shaw PJ, Gillingwater TH, Azzouz M & Ning K (2015) . Molecular Therapy, 23(2), 270-277.
Raman R, Allen SP, Goodall EF, Kramer S, Ponger L-L, Heath PR, Milo M, Hollinger HC, Walsh T, Highley JR , Olpin S et al (2015) . Neuropathology and Applied Neurobiology, 41(2), 201-226.
Mulcahy PJ, Binny C, Muszynski B, Karyka E & Azzouz M (2015) , 1-22.
Sharp PS, Shaw K, Boorman L, Harris S, Kennerley AJ, Azzouz M & Berwick J (2015) . Scientific Reports, 5(1).
(2015) . The Lancet Neurology, 14(7), 690-690.
Marino M, Papa S, Crippa V, Nardo G, Peviani M, Cheroni C, Trolese MC, Lauranzano E, Bonetto V, Poletti A , DeBiasi S et al (2015) . Neurobiology of Aging, 36(1), 492-504.
Agosta F, Al-Chalabi A, Filippi M, Hardiman O, Kaji R, Meininger V, Nakano I, Shaw P, Shefner J, van den Berg LH & Ludolph A (2015) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(1-2), 1-7.
Beer AM, Cooper-Knock J, Higginbottom A, Highley JR, Wharton SB, Ince PG, Milano A, Jones AA, Al-Chalabi A, Kirby J & Shaw PJ (2015) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(3-4), 249-251.
McGeachan AJ, Hobson EV, Shaw PJ & McDermott CJ (2015) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(1-2), 108-113.
Balendra R, Jones A, Jivraj N, Steen IN, Young CA, Shaw PJ, Turner MR, Leigh PN & Al-Chalabi A (2015) . Journal of Neurology, Neurosurgery & Psychiatry, 86(1), 45-49.
Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG & Wharton SB (2014) . Neuropathology and Applied Neurobiology, 40(7), 802-814.
Ramesh TM, Shaw PJ & McDearmid J (2014) . Journal of Neurology, Neurosurgery & Psychiatry, 85(11), 1288-1289.
Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW , Calini D et al (2014) . Neuron, 84(2), 324-331.
Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J , McDermott CJ et al (2014) . Neuropathology and Applied Neurobiology, 40(6), 670-685.
Bennett EJ, Mead RJ, Azzouz M, Shaw PJ & Grierson AJ (2014) . PLoS ONE, 9(9), e107918-e107918.
Jenkins TM, Hollinger H & McDermott CJ (2014) . Current Opinion in Neurology, 27(5), 524-531.
Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J , Hautbergue GM et al (2014) . Brain, 137(7), 2040-2051.
Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH, van Es MA , Pasterkamp RJ et al (2014) . Annals of Neurology, 76(1), 120-133.
Allen SP, Rajan S, Duffy L, Mortiboys H, Higginbottom A, Grierson AJ & Shaw PJ (2014) . Neurobiology of Aging, 35(6), 1499-1509.
Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ & McDermott CJ (2014) . BMJ Supportive & Palliative Care, 6(1), 52-59.
Mulcahy PJ, Iremonger K, Karyka E, Herranz-Martín S, Shum K-T, Tam JKV & Azzouz M (2014) . Human Gene Therapy, 25(7), 575-586.
Tam JKV, Karyka E & Azzouz M (2014) . Expert Opinion on Orphan Drugs, 2(5), 465-476.
Cooper-Knock J, Walsh M, Higginbottom A, Highley JR, Bury J, Dickman M, Rattray M, Heath P, Wyles M, Ince P , Wharton S et al (2014) . Neurology, 82(10_supplement).
Cooper-Knock J, Walsh M, Higginbottom A, Highley JR, Bury J, Dickman M, Rattray M, Heath P, Wyles M, Ince P , Wharton S et al (2014) . Neurology, 82(10_supplement).
Highley JR, Gebril OH, Simpson JE, Wharton SB, Kirby J, O'Brien JT, Barber R, Kalaria RN, Brayne C, Lewis CE , Shaw PJ et al (2014) . Journal of Aging Science, 2(1).
Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ & McDermott CJ (2014) . BMJ Supportive & Palliative Care, 4(1), 57-63.
Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B , Rohrer JD et al (2014) . Acta Neuropathologica, 127(3), 407-418.
Lehnert S, Costa J, de Carvalho M, Kirby J, Kuzma-Kozakiewicz M, Morelli C, Robberecht W, Shaw P, Silani V, Steinacker P , Tumani H et al (2014) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 15(5-6), 344-350.
Yang D-J, Wang X-L, Ismail A, Ashman CJ, Valori CF, Wang G, Gao S, Higginbottom A, Ince PG, Azzouz M , Xu J et al (2014) . Cell Death and Disease, 5(2).
Jones AR, Jivraj N, Balendra R, Murphy C, Kelly J, Thornhill M, Young C, Shaw PJ, Leigh PN, Turner MR , Steen IN et al (2014) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 15(3-4), 285-291.
Cooper-Knock J, Shaw PJ & Kirby J (2014) . Acta Neuropathologica, 127(3), 333-345.
Lenglet T, Lacomblez L, Abitbol JL, Ludolph A, Mora JS, Robberecht W, Shaw PJ, Pruss RM, Cuvier V & Meininger V (2014) . European Journal of Neurology, 21(3), 529-536.
Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J , Burghes AH et al (2014) . Proceedings of the National Academy of Sciences, 111(2), 829-832.
Alix JJP & Shaw PJ (2014) , 329-350.
Wood-allum CA & Shaw PJ (2014) , 703-735.
Fogh I, Ratti A, Gellera C, Lin K, Tiloca C, Moskvina V, Corrado L, Soraru G, Cereda C, Corti S , Gentilini D et al (2014) . Human Molecular Genetics, 23(8), 2220-2231.
Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ & McDermott CJ (2013) . Journal of Palliative Medicine, 16(12), 1602-1609.
Gibbons CJ, Thornton EW, Ealing J, Shaw PJ, Talbot K, Tennant A & Young CA (2013) . Journal of the Neurological Sciences, 334(1-2), 112-118.
Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE , Brayne C et al (2013) . Neuropathology and Applied Neurobiology, 39(7), 788-799.
Christou YA, Ohyama K, Placzek M, Monk PN & Shaw PJ (2013) . BMC Neuroscience, 14(1).
Cooper-Knock J, Higginbottom A, Connor-Robson N, Bayatti N, Bury JJ, Kirby J, Ninkina N, Buchman VL & Shaw PJ (2013) . Neurology, 81(19), 1719-1721.
Cooper-Knock J, Jenkins T & Shaw PJ (2013) . Colloquium Series on Genomic and Molecular Medicine, 2(2), 1-60.
Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ & Bendotti C (2013) . Brain, 136(11), 3305-3332.
Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ & McDermott CJ (2013) . Palliative Medicine, 27(9), 878-878.
Hickman SJ, Allen JA, Baisre A, Batty R, Lari HB, Melen O, Pepper IM, Sarrigiannis PG, Turbin RE, Wharton SB & McDermott CJ (2013) . Neuro-Ophthalmology, 37(4), 146-156.
Cooper-Knock J, Frolov A, Highley JR, Charlesworth G, Kirby J, Milano A, Hartley J, Ince PG, McDermott CJ, Lashley T , Revesz T et al (2013) . Neurology, 81(9), 808-811.
Kirby J, Highley JR, Cox L, Goodall EF, Hewitt C, Hartley JA, Hollinger HC, Fox M, Ince PG, McDermott CJ & Shaw PJ (2013) . Neuropathology and Applied Neurobiology, 39(5), 562-571.
Sarkozy A, Hicks D, Hudson J, Laval SH, Barresi R, Hilton-Jones D, Deschauer M, Harris E, Rufibach L, Hwang E , Bashir R et al (2013) . Human Mutation, 34(8), 1111-1118.
Gibbons C, Thornton E, Ealing J, Shaw P, Talbot K, Tennant A & Young C (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(7-8), 537-545.
Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I , Brancale A et al (2013) . Free Radical Biology and Medicine, 61, 438-452.
Jenkins TM, Burness C, Connolly DJ, Rao DG, Hoggard N, Mawson S, McDermott CJ, Wilkinson ID & Shaw PJ (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(5-6), 414-423.
Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL , Rutkove SB et al (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(sup1), 19-32.
Groen EJN, Fumoto K, Blokhuis AM, Engelen-Lee J, Zhou Y, van den Heuvel DMA, Koppers M, van Diggelen F, van Heest J, Demmers JAA , Kirby J et al (2013) . Human Molecular Genetics, 22(18), 3690-3704.
Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM, Gorrie G , Hanemann CO et al (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(7-8), 521-527.
Mok K, Laaksovirta H, Tienari PJ, Peuralinna T, Myllykangas L, Chiò A, Traynor BJ, Nalls MA, Gurunlian N, Shatunov A , Restagno G et al (2013) . European Journal of Human Genetics, 21(12), 1429-1435.
Buchman VL, Cooper-Knock J, Connor-Robson N, Higginbottom A, Kirby J, Razinskaya OD, Ninkina N & Shaw PJ (2013) . Molecular Neurodegeneration, 8(1), 12-12.
Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ & McDermott CJ (2013) . Palliative Medicine, 27(6), 516-523.
Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H , Nicholson G et al (2013) . LANCET NEUROLOGY, 12(3), 310-322.
Hewamadduma CAA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T & Shaw PJ (2013) . Human Molecular Genetics, 22(12), 2376-2386.
Lo C, Cooper-Knock J, Garrard K, Martindale J, Williams T & Shaw P (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(5-6), 473-475.
Nanou A, Higginbottom A, Valori CF, Wyles M, Ning K, Shaw P & Azzouz M (2013) . Molecular Therapy, 21(8), 1486-1496.
Jones AR, Woollacott I, Shatunov A, Cooper-Knock J, Buchman V, Sproviero W, Smith B, Scott KM, Balendra R, Abel O , McGuffin P et al (2013) . Neurobiology of Aging, 34(9), 2234.e1-2234.e7.
(2013) . The Lancet Neurology, 12(4), 339-345.
van Rheenen W, Diekstra FP, van Doormaal PTC, Seelen M, Kenna K, McLaughlin R, Shatunov A, Czell D, van Es MA, van Vught PWJ , van Damme P et al (2013) . Neurobiology of Aging, 34(5), 1517.e5-1517.e7.
McGown A, McDearmid JR, Panagiotaki N, Tong H, Al Mashhadi S, Redhead N, Lyon AN, Beattie CE, Shaw PJ & Ramesh TM (2013) . Annals of Neurology, 73(2), 246-258.
Brockington A, Ning K, Heath PR, Wood E, Kirby J, Fusi N, Lawrence N, Wharton SB, Ince PG & Shaw PJ (2013) . Acta Neuropathologica, 125(1), 95-109.
Ismail A, Cooper-Knock J, Highley JR, Milano A, Kirby J, Goodall E, Lowe J, Scott I, Constantinescu CS, Walters SJ , Price S et al (2013) . Journal of Neurology, Neurosurgery & Psychiatry, 84(1), 79-87.
Stavroulakis T, Walsh T, Shaw PJ & McDermott CJ (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(2), 96-104.
Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ & McDermott CJ (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(2), 105-110.
Smith BN, Newhouse S, Shatunov A, Vance C, Topp S, Johnson L, Miller J, Lee Y, Troakes C, Scott KM , Jones A et al (2013) . European Journal of Human Genetics, 21(1), 102-108.
Aridegbe T, Kandler R, Walters SJ, Walsh T, Shaw PJ & McDermott CJ (2013) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14(1), 13-19.
Wang L, Chierico L, Little D, Patikarnmonthon N, Yang Z, Azzouz M, Madsen J, Armes SP & Battaglia G (2012) . Angewandte Chemie International Edition, 51(44), 11122-11125.
McDermott CJ, Maguire C, Cooper CL, Ackroyd R, Baird WO, Baudouin S, Bentley A, Bianchi S, Bourke S, Bradburn MJ , Dixon S et al (2012) . BMC Neurology, 12(1).
Cooper-Knock J, Kirby J, Ferraiuolo L, Heath PR, Rattray M & Shaw PJ (2012) . Nature Reviews Neurology, 8(9), 518-530.
Rafiq MK, Bradburn M, Proctor AR, Billings C, Bianchi S, McDermott CJ & Shaw PJ (2012) . Amyotrophic Lateral Sclerosis, 13(6), 528-532.
Ismail A, Ning K, Al-Hayani A, Sharrack B & Azzouz M (2012) . Translational Neuroscience, 3(2).
Rafiq MK, Proctor AR, McDermott CJ & Shaw PJ (2012) . Practical Neurology, 12(3), 166-176.
(2012) . Amyotrophic Lateral Sclerosis, 13(3), 331-331.
Majounie E, Renton AE, Mok K, Dopper EGP, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J , van Swieten JC et al (2012) . The Lancet Neurology, 11(4), 323-330.
Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J , van Swieten JC et al (2012) Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. The Lancet Neurology.
Bourke SC, O'Neill CL, Williams TL, Peel ET, Gibson GJ, McDermott CJ & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, 83(4), 368-369.
Hughes P, Seymour L, Hollinger H, Evans J, McDermott C & Shaw P (2012) . BMJ Supportive & Palliative Care, 2(Suppl 1), A102.3-A103.
Cooper-Knock J, Hewitt C, Highley JR, Brockington A, Milano A, Man S, Martindale J, Hartley J, Walsh T, Gelsthorpe C , Baxter L et al (2012) . Brain, 135(3), 751-764.
Harwood CA, McDermott CJ & Shaw PJ (2012) . Medicine, 40(10), 540-545.
Mok K, Traynor BJ, Schymick J, Tienari PJ, Laaksovirta H, Peuralinna T, Myllykangas L, Chiò A, Shatunov A, Boeve BF , Boxer AL et al (2012) . Neurobiology of Aging, 33(1), 209.e3-209.e8.
O'Neill CL, Williams TL, Peel ET, McDermott CJ, Shaw PJ, Gibson GJ & Bourke SC (2012) . Journal of Neurology, Neurosurgery & Psychiatry, 83(4), 371-376.
Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A & Young CA (2011) . Health and Quality of Life Outcomes, 9(1).
Ince PG, Highley JR, Kirby J, Wharton SB, Takahashi H, Strong MJ & Shaw PJ (2011) . Acta Neuropathologica, 122(6), 657-671.
Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ & Ince PG (2011) . Neuroscience Letters, 505(1), 25-30.
Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ & Ince PG (2011) Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: A study in the MRC-CFAS population neuropathology cohort. Neuroscience Letters.
Ferraiuolo L, Kirby J, Grierson AJ, Sendtner M & Shaw PJ (2011) . Nat Rev Neurol, 7(11), 616-630.
Ismail A, Sharrack B, Constantinescu C, McDermott C & Shaw P (2011) Multiple sclerosis and amyotrophic lateral sclerosis - what is the link? A case series of six patients. MULTIPLE SCLEROSIS JOURNAL, 17, S472-S472.
Ning K, Drepper C, Valori CF, Wyles M, Ismail A, Higginbottom A, Herrmann T, Shaw PJ, Sendtner M & Azzouz M (2011) PTEN signalling in motor neuron disease (ALS & SMA). HUMAN GENE THERAPY, 22(10), A64-A64.
Nanou A, Higginbottom A, Wyles M, Ning K, Shaw P & Azzouz M (2011) Gene therapy approaches to evaluate neuroprotection in experimental models of Amyotrophic Lateral Sclerosis. HUMAN GENE THERAPY, 22(10), A64-A64.
Simpson JE, Ince PG, Shaw PJ, Heath PR, Raman R, Garwood CJ, Gelsthorpe C, Baxter L, Forster G, Matthews FE , Brayne C et al (2011) . Neurobiology of Aging, 32(10), 1795-1807.
Sargsyan SA, Blackburn DJ, Barber SC, Grosskreutz J, De Vos KJ, Monk PN & Shaw PJ (2011) . BMC Neuroscience, 12(1).
Mok K, Traynor BJ, Schymick J, Tienari PJ, Laaksovirta H, Peuralinna T, Myllykangas L, Chiò A, Shatunov A, Boeve BF , Boxer AL et al (2011) The chromosome 9 ALS and FTD locus is probably derived from a single founder. Neurobiology of Aging.
Rafiq M, Sharrack N, Shaw PJ & Hadjivassiliou M (2011) . Practical Neurology, 11(5), 296-300.
Ferraiuolo L, Higginbottom A, Heath PR, Barber S, Greenald D, Kirby J & Shaw PJ (2011) . Brain, 134(9), 2627-2641.
Mead RJ, Bennett EJ, Kennerley AJ, Sharp P, Sunyach C, Kasher P, Berwick J, Pettmann B, Battaglia G, Azzouz M , Grierson A et al (2011) . PLoS ONE, 6(8).
O'Neill CL, Williams TL, Peel ET, McDermott CJ, Shaw PJ, John G & Bourke SC (2011) Non-invasive ventilation in motor neuron disease: An update of current UK practice. Journal of Neurology, Neurosurgery and Psychiatry.
Simpson J, Ince P, Heath P, Raman R, Garwood C, Shaw P, Gelstorpe C, Baxter L, Forster G, Fiona M , Savva G et al (2011) . Alzheimer's & Dementia, 7(4S_Part_16).
Duffy LM, Chapman AL, Shaw PJ & Grierson AJ (2011) . Neuropathology and Applied Neurobiology, 37(4), 336-352.
Cooper-Knock J, Ahmedzai SH & Shaw P (2011) . Amyotrophic Lateral Sclerosis, 12(6), 464-465.
Barber SC, Wood-Allum CA, Sargsyan SA, Walsh T, Cox LE, Monk PN & Shaw PJ (2011) . Amyotrophic Lateral Sclerosis, 12(4), 257-263.
Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo S-W, Valori CF, Cox L, Sharrack B, Wharton SB , Ince PG et al (2011) . Brain, 134(2), 506-517.
Shaw PJ, Otto M, Bowser R, Turner M, Berry J, Brettschneider J, Connor J, Costa J, Cudkowicz M & Glass J (2011) . Amyotrophic Lateral Sclerosis.
Al-Chalabi A, Shaw PJ, Young CA, Morrison KE, Murphy C, Thornhill M, Kelly J, Steen IN & Leigh PN (2011) . BMC Neurology, 11.
Shaw PJ, Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Talbot K, Tennant A & Young CA (2011) . Health and Quality of Life Outcomes.

Chapters

Shaw PJ & Kirby J (2024) INTERNATIONAL REVIEW OF NEUROBIOLOGY Motor Neurone Disease Preface, MOTOR NEURONE DISEASE (pp. XIX-XX).
Shaw PJ & Kirby J (2024) , International Review of Neurobiology (pp. xix-xx). Elsevier
Verber N & Shaw PJ (2021) , Aminoff's Neurology and General Medicine (pp. 285-302). Elsevier
Chandran JS, Scarrott JM, Shaw P & Azzouz M (2017) Gene Therapy in the Nervous System: Failures and Successes In El-Khamisy S (Ed.), Personalised Medicine Lessons from Neurodegeneration to Cancer Springer
Allen C, Shaw PJ & Ferraiuolo L (2017) In El-Khamisy (Ed.), Personalised Medicine
Chandran JS, Scarrott JM, Shaw PJ & Azzouz M (2017) , Advances in Experimental Medicine and Biology (pp. 241-257). Springer International Publishing
Hardiman O, Kelly JA, Bak TH, Elamin M, Mihaila DL, Shaw PJ, Mitsumoto H & Shefner JM (2016) , Neurodegenerative Disorders (pp. 289-303). Springer International Publishing
Abrams GM, Albers GW, Alix JJP, Aminoff MJ, Bharucha AE, Batla A, Benson CM, Betjemann JP, Brosch JR, Camilleri M , Chen R et al (2014) , Aminoff's Neurology and General Medicine (pp. vii-xii). Elsevier
Abrams CS, Accurso FJ, Afdhal NH, Akin C, Aksamit AJ, Al-Awqati Q, Allos BM, Altshuler D, Aminoff MJ, Anderson JL , Anderson KE et al (2012) , Goldman's Cecil Medicine (pp. ix-xxx). Elsevier
Shaw PJ (2012) , Goldman's Cecil Medicine (pp. 2343-2347). Elsevier
Shaw PA & Bryant RG (2011) (pp. 373-401). Wiley
Shaw PJ, Cooper-Knock J, Bury JJ, Ferraiuolo L, Goodall EF & Kirby J (2011) Gene Expression Profiling and its Application in Amyotrophic Lateral Sclerosis InTech Open Access
Shaw PJ & Wood-Allum C (2011) The Neurology of Thyroid Disease In Aminoff M (Ed.), Neurology of Systemic Disease

Conference proceedings papers

Hartopp N, Thoma A, Mossman E, Ellis L, Hughes R, Bhosale G, Gandini A, Pristera A, Doe C, Allen S , Ferraiuolo L et al (2024) . I: Experimental therapeutics – preclinical (pp A152.1-A152)
Ryan C, Shaw P & Shorey P (2023) . Posters
Miller TM, Cudkowicz M, Genge A, Shaw PJ, Sobue G, Fanning L, Gambino G, Garafalo S, Nestorov I, Graham D , Inra J et al (2023) Two-Year Results from the Open-Label Extension of VALOR: Tofersen in Adults with SOD1-ALS. MUSCLE & NERVE, Vol. 68 (pp S1-S2)
Milanese M, Provenzano F, Balbi M, Giunti D, Nyberg S, Parodi B, Bacchetti F, Torazza C, Bonifacino T, Usai C , de Rosbo NK et al (2023) In-vitro and in-vivo evidence supporting the therapeutic effect of extracellular vesicles derived from mesenchymal stem cells in amyotrophic lateral sclerosis. GLIA, Vol. 71 (pp E280-E281)
Bell S, De Marco M, Barnes K, Shaw P, Ferraiuolo L, Blackburn D, Mortiboys H & Venneri A (2020) Do deficits in Mitochondrial Spare Respiratory Capacity contribute to Neuropsychological changes seen in Alzheimer's disease?. NEUROLOGY, Vol. 94(15)
Allen SP, Hall B, Castelli L, Francis L, Woof R, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Webster CP , De Vos K et al (2018) . Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1859 (pp e23-e23)
Hewamadduma CA, Omalley R, Robinson M, Beauchamp N, Rogers T, Martindale J, Mcdermott C, Shaw P, Hoggard N & Hadjivassiliou M (2017) . Journal of the Neurological Sciences, Vol. 381 (pp 304-305)
Jenkins T, Alix J, Rao G, Hoggard N, O'Brien E, Baster K, Bradburn M, Bigley J, McDermott C, Wilkinson I & Shaw P (2017) . Journal of the Neurological Sciences, Vol. 381 (pp 102-102)
(2016) . The Journal of Pathology, Vol. 240 (pp S1-S48)
Iannitti T, Scarrot JM, Coldicott IRP, Kaspar BK, Ferraiuolo L, Shaw PJ & Azzouz M (2016) Gene Therapy for Familial ALS Using AAV9 Mediated Silencing of Mutant SOD1. HUMAN GENE THERAPY, Vol. 27(7) (pp A12-A12)
Herranz-Martin S, Lewis KE, Coldicott I, Chandran JS, Lukashchuk V, Iannitti T, Shaw PJ & Azzouz M (2016) Experimental modelling of ALS by AAV-mediated in vivo modulation of the C9ORF72 gene. HUMAN GENE THERAPY, Vol. 27(7) (pp A16-A16)
Lorente-Pons A, Wood JD, Shaw PJ, Ince PG, Cooper-Knock J, Ramachandran A, Kirby J & Highley JR (2016) . NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 42(S1) (pp 28-28), 2 March 2016 - 4 March 2016.
Rafiq M, Proctor A, McDermott C & Shaw P (2015) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 86(11) (pp e4.54-e4)
Hewamadduma C, Grierson A, Higginbottom A & Shaw P (2015) . Journal of the Neurological Sciences, Vol. 357 (pp e49-e49)
Rafiq M, Lee E, Bradburn M, McDermott C & Shaw P (2015) Elevated creatine kinase is associated with a better prognosis in patients with amyotrophic lateral sclerosis. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 741-741)
Rafiq M, Bradburn M, McDermott C & Shaw P (2015) Effects of cough augmentation on pulmonary morbidity, survival, and quality of life in patients with amyotrophic lateral sclerosis in respiratory failure: a randomised trial. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 244-244)
Lorente-Pons A, Wood JD, Shaw PJ, Ince PG, Cooper-Knock J, Ramachandran A, Kirby J & Highley JR (2015) Investigating the mechanisms underlying oligodendrocyte dysfunction in C9ORF72 ALS. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 41 (pp 26-27)
Beer A, Cooper-Knock J, Higginbottom A, Robin Highley J, Wharton SP, Milano A, Jones A, Al-Chalabi A, Kirby J & Shaw PJ (2014) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(10) (pp e4.130-e4)
Rafiq MK, Bradburn M, Proctor A, Billings C, Bianchi S, McDermott C & Shaw P (2014) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(10) (pp e4.93-e4)
Simpson JE, Ince PG, Matthews F, Shaw PJ, Heath PR, Brayne C, Garwood C, Abdalla H, Higginbottom A & Wharton SB (2014) A neuronal DNA damage response is detected at low Braak stages and correlates with cognitive impairment in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 40 (pp 31-32)
Rafiq M, Lee E, Bradburn M, McDermott C & Shaw P (2013) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 84(11) (pp e2.135-e2)
Binny C, Karyka E, Ning K, Bennett E, Ince P, Shaw P & Azzouz M (2013) Efficient scAAV9-mediated delivery of SMN to motor neurons in neonatal and juvenile mice. HUMAN GENE THERAPY, Vol. 24(5) (pp A38-A38)
Little D, Valori C, Wyles M, Shaw P, Azzouz M & Ning K (2013) Systemic delivery of scAAV9 expressing PTEN siRNA prolongs survival in a model of spinal muscular atrophy. HUMAN GENE THERAPY, Vol. 24(5) (pp A27-A27)
Highley JR, Cooper-Knock J, Frolov A, Charlesworth G, Kirby J, Wharton SB, Ince PG, Shaw PJ, Wood N & Bandman O (2013) A pathological basis for the association of parkinsonism and amyotrophic lateral sclerosis. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 39 (pp 51-51)
Cooper-Knock J, Highley JR, Hartley J, Milano A, Sawcer S, Compston A, Frolov A, Charlesworth G, Wood N, Bandmann O , McDermott CJ et al (2013) . The Lancet, Vol. 381 (pp S32-S32)
Woollacott I, Shatunov A, Jones A, Morrison KE, Leigh PN, Shaw PJ, Shaw CE & Al-Chalabi A (2013) . The Lancet, Vol. 381 (pp S116-S116)
Rafiq M, Proctor AR, McDermott CJ & Shaw P (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A32.3-A33)
Al-Chalabi A, Shaw P, Kelly J, Morrison K, Murphy C, Thornhill M, Steen N & Leigh PN (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A31.3-A31)
Gibbons CJ, Cousins R, Pomeroy IM, Ando H, Al-Chalabi A, Chataway J, Constaninescu C, Ealing J, Hawkins C, Morrison K , Palace J et al (2012) Work in progress: quality of life (QoL) and neurological disease - trajectories of outcome in neurological conditions (TONiC): a study protocol. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 19 (pp 264-264)
Hewamadduma C, Grierson A, Moens C, Pan L, Ma T, Ingham P, Ramesh T & Shaw P (2012) . Neurology, Vol. 78(Meeting Abstracts 1) (pp P03.180-P03.180)
Hewamadduma C, Grierson A, Moens C, Pan L, Ma T, Ingham P, Ramesh T & Shaw P (2012) . Neurology, Vol. 78(Meeting Abstracts 1)
Hewamadduma C, Higgenbottom CAA, Moens C, Helde K, Raman R, Tennore R, Grierson A & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.116-e1)
Aridegbe T, Kandler R, Walsh T, Shaw PJ & McDermott CJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.108-e1)
Brockington A, Ning K, Heath P, Wood E, Malik K, Fusi N, Wharton S, Ince PG & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.110-e1)
Rajan S, Shaw P & Wood-Allum C (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.26-e1)
Ramesh T, McGown A, Al Mashhadi S, Redhead N, Lyon A, Bettie CE & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.122-e1)
Ferraiuolo L, Higginbottom A, Heath PR, Barber S, Greenald D, Kirby J & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.115-e1)
McDermott C, Proctor A, Walsh T, Ackroyd R, Rao G, Bianchi S, Englert L, Rafiq MK & Shaw PJ (2012) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(3) (pp e1.120-e1)
Smith BN, Topp S, Barwell J, Al-Chalabi A, Kirby J, Shaw PJ, Paul H, Morrison KE, de Jong V, Baas F , Lewis CM et al (2012) Age-dependent penetrance and anticipation in ALS+/-FTLD kindreds due to C9ORF72 hexanucleotide intronic repeat expansion mutations (C9HIREM). DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, Vol. 33 (pp 282-282)
Smith BN, Topp S, Barwell J, Al-Chalabi A, Kirby J, Shaw PJ, Paul H, Morrison KE, de Jong V, Baas F , Lewis CM et al (2012) Age-dependent penetrance and anticipation in ALS+/-FTLD kindreds due to C9ORF72 hexanucleotide intronic repeat expansion mutations (C9HIREM). DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, Vol. 33 (pp 36-37)
Baxter SK, Baird WO, Thompson S, Bianchi S, Walters S, Ahmedzai SH, Proctor A, Shaw PJ & McDermott CJ (2012) The Use of Non-Invasive Ventilation for Patients with Motor Neurone Disease: Patient and Carer Perceptions of Obstacles and Outcomes. ANNALS OF NEUROLOGY, Vol. 72 (pp S73-S74)
Simpson JE, Ince PG, Shaw PJ, Heath PR, Raman R, Garwood CJ, Gelsthorpe C, Baxter L, Forster G, Matthews FE , Brayne C et al (2011) Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype. Neurobiology of Aging
Bunting E, Wood-Allum C, Barber S & Shaw P (2011) Congruent handedness and side of onset in ALS-evidence in favour of the exercise hypothesis?. JOURNAL OF NEUROLOGY, Vol. 258 (pp 57-57)
Eckmann J, Eckert SH, Leuner K, Bordet T, Pruss R, Grierson A, Shaw P, Clemens L, Nguyen HP, Mueller WE & Eckert GP (2011) Impact of Olesoxime on disease related mitochondrial membrane properties in mouse models of neurodegenerative diseases. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, Vol. 383 (pp 51-51)
Simpson JE, Ince PG, Heath PR, Raman R, Shaw PJ, Gelsthorpe C, Baxter L, Forster G, Matthews F, Savva G , Brayne C et al (2011) Microarray analysis of the astrocyte transcriptome in the ageing brain: relationship to Alzheimer's pathology and ApoE genotype. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 33-33)
Highley R, Kirby J, Jansweijer JA, Heath PR, Shaw PJ & Ince PG (2011) TARDBP mutations, amyotrophic lateral sclerosis and alternative splicing. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 20-20)

Other

McDermott CJ & Bradburn MJ (2016) . The Lancet Neurology, 15(6), 543-544.

Preprints

Grant OA, Iacoangeli A, Zwamborn RAJ, van Rheenen W, Byrne R, Van Eijk KR, Kenna K, van Vugt JJFA, Cooper-Knock J, Kenna B , Vural A et al (2024) , Cold Spring Harbor Laboratory.
Weinreich M, McDonough H, Yacovzada N, Magen I, Cohen Y, Harvey C, Gornall S, Boddy S, Alix J, Mohseni N , Kurz JM et al (2024) , Cold Spring Harbor Laboratory.
Pham TK, Verber N, Turner MR, Malaspina A, Collins MO, Mead RJ & Shaw PJ (2024) , Cold Spring Harbor Laboratory.
McKinnon S, Qiang Z, Keerie A, Wells T, Shaw PJ, Alix JJP & Mead RJ (2024) , Cold Spring Harbor Laboratory.
Zhang S, Moll T, Rubin-Sigler J, Tu S, Li S, Yuan E, Liu M, Butt A, Harvey C, Gornall S , Alhalthli E et al (2024) , Cold Spring Harbor Laboratory.
Iacoangeli A, Dilliott AA, Al Khleifat A, Andersen PM, Başak NA, Cooper-Knock J, Corcia P, Couratier P, de Carvalho M, Drory V , Glass JD et al (2024) , Cold Spring Harbor Laboratory.
Lin Y-H, Dodd JE, Cutillo L, Castelli LM, Mihaylov SR, Norris K, Higginbottom A, Walsh MJ, Cooper-Knock J, Highley JR , Granata I et al (2024) , Cold Spring Harbor Laboratory.
Burrows DJ, McGown A, Abduljabbar O, Castelli LM, Shaw PJ, Hautbergue GM & Ramesh TM (2024) , Cold Spring Harbor Laboratory.
Michael B, Wood G, Sargent B, Ahmad Z-U-A, Tharmaratnam K, Dunai C, Egbe F, Martin N, Facer B, Pendered S , Rogers H et al (2024) , Research Square Platform LLC.
Kalia M, Spargo TP, Al Khleifat A, Opie-Martin S, Kabiljo R, Dobson RJB, van Damme P, Corcia P, Couratier P, Hardiman O , McLaughlin R et al (2023) , Cold Spring Harbor Laboratory.
Spargo TP, Marriott H, Hunt GP, Pain O, Kabiljo R, Bowles H, Sproviero W, Gillett AC, Fogh I, Andersen PM , Başak NA et al (2023) , Cold Spring Harbor Laboratory.
Bell SM, Wareing H, Hamshaw A, De S, New E, Shaw PJ, De Marco M, Venneri A, Blackburn DJ, Ferraiuolo L & Mortiboys H (2023) , Cold Spring Harbor Laboratory.
Kalia M, Miotto M, Ness D, Opie-Martin S, Spargo TP, Di Rienzo L, Biagini T, Petrizzelli F, Al-Khleifat A, Kabiljo R , Topp S et al (2022) , Cold Spring Harbor Laboratory.
Marriott H, Spargo TP, Khleifat AA, Fogh I, Andersen PM, Başak NA, Cooper-Knock J, Corcia P, Couratier P, de Carvalho M , Drory V et al (2022) , Cold Spring Harbor Laboratory.
Adey BN, Cooper-Knock J, Khleifat AA, Fogh I, van Damme P, Corcia P, Couratier P, Hardiman O, McLaughlin R, Gotkine M , Drory V et al (2022) , Cold Spring Harbor Laboratory.
Byrne RP, van Rheenen W, van den Berg LH, Veldink JH & McLaughlin RL (2020) , Cold Spring Harbor Laboratory.

Research group

Adrian Higginbottom
Laura Evans
Aytac Gul
Ilaria Giovanelli
Simon Bell
Anushka Bharkava
Marco Destro
Ana Aragon Gonzalez
Allan Shaw
Tobi Moll
Calum Harvey
Selina Beal
Kriti Gupta
Kayal Mujthukrishnan
Deborati Bhattachryya
Ekene Anakor
Thomas Marlow
Raquel Rua Martins
Aoife Kernan
Laura Chapman

SITraN PI Scientific Collaborators

Laura Ferraiuolo
Robin Highley
Richard Mead
Janine Kirby
Scott Allen
Guillaume Hautbergue
Mimoun Azzouz
Johnathan Cooper-Knock
James Alix
Tennore Ramesh
Ryan West
Kurt de Vos
Christopher McDermott

Current Clinical Research Team

Mbombe Kazoka
Lee Tuddenham
Madalina Roman
Mary Sikaonga
James Alix
Stacy Young
Johnathan Cooper-Knock
Calum Harvey
Daniel Madarshahian
Aoife Kernan

Grants

Principal Funding Sources

The Motor Neurone Disease Association
The Medical Research Council
LifeArc
NIHR
My Name’5 Doddie Foundation
European Union
Pharmaceutical partners

Professional activities and memberships

Professor Shaw has served as a member of multiple national and international committees, and has been a research advisory panel member for the Wellcome Trust, MNDA, MRC, the Muscular Dystrophy Association, the Academy of Medical Sciences, the Academy of Science Finland, NIHR and reviews for multiple grant awarding bodies.

Current Membership of National and International Committees

Academy of Medical Sciences New Lectureship Panel Fellowship Panel 2020 - present.
Lister Institute Board of Governors 2018 – present
UKRI Future Leaders Fellowship Panel and College 2020- present
NIHR Senior fellowship panel 2021 – present

Postgraduate awards

2022 British Neuroscience Association Award for Outstanding Contribution to Neuroscience
2022 Award of the 2^nd Dr M Gourie Devi Oration, National Institute of Mental Health and Neuroscience, Bengaluru, India
2022 Oktoberfest Plenary Lecture, Ludwig-Maximilian University of Munich

2021 Singhal award Lecture XXV World Congress of Neurology, Rome.
2019 National Queen’s Anniversary Prize 2019 for excellence and innovation in Neuroscience awarded to the 91ֱ�� Institute for Translational Neuroscience.
2019 European Academy of Neurology Moritz Romberg Lecture
2019 Association of British Neurologists 2019 Medallist
2018/19 The Physiological Society GL Brown Prize Lectures
2018 Science and Society Public Lecture University of Liverpool, June 2018.
2017 Honorary Doctor of Medicine, University of Sussex in recognition of major contribution to the field of Neurology.
2017 Kosterlitz Prize and Lecture, University of Aberdeen.
2017 Honorary Degree, University of Bradford for internationally recognized work in the field of Neurology and instrumental work in setting standards of excellence in the clinical care for patients.
2017 Honorary Doctor of Medicine, University of Sussex in recognition of major contribution to the field of Neurology.
2017 University of Sussex Brain Visiting Professorship
2017 Kosterlitz Lecture, University of Aberdeen.
2016 Croonian Lecture, UK Royal College of Physicians
2015 Osler Lecture, Association of Physicians of the United Kingdom and Ireland
2015 Elected Fellow of the American Association for the Advancement of Science for groundbreaking basic and translational research of relevance to the understanding and treatment of neurodegenerative diseases.
2014 Dame Commander of the Order of the British Empire (DBE) for services to Neuroscience
2014 Jacobson Visiting Professorship, University of Newcastle upon Tyne
2013 Alfred Meyer’s Memorial Award Lecture British Neuropathological Society
2013 NIHR Senior Investigator Award
2013 UK ACCEA Platinum Clinical Excellence Award
2012 Gary and Peggy Edwards Distinguished Visiting Professorship for ALS, Houston USA
2012 Elected President of the North of England Neurological Association
2012 Visiting Professorship, Association of Physicians (Kerala Chapter) India
2012 Elected to membership of the Medical Pilgrims
2007 The International ALS/MND Forbes Norris Award for excellence in research and compassion in clinical care
2007 Fellowship of the Academy of Medical Sciences
2007 Spinoza Visiting Professorship, University of Amsterdam
2006 Royal College of Physicians Jean Hunter Prize for research into nervous disorders
2004 Invited Fellowship of the American Neurological Association
2001 American Academy of Neurology and ALS Association Sheila Essey Award for outstanding research contribution in amyotrophic lateral sclerosis/ motor neurone disease
2000 Hong Kong Neurological Association Li Po Shan/ Dr Vincent Liu visiting Professorship
1997 Invited Fellowship of the American Academy of Neurology
1996 Renewal of Wellcome Senior Fellowship in Clinical Science
1995 British Medical Association Vera Down Award
1992 Poster Research prize at the Third International Symposium on ALS/MND
1991 Award of Wellcome Senior Fellowship in Clinical Science
1991 Association of British Neurologists Sir Charles Symonds Prize
1990 North of England Neurological Association Liversedge Research Prize
1985 Northern Regional Health Authority David Dickson Research Prize
1985 Association of Physicians UK Dewar Research Prize
1985 British Cardiac Society Young Investigator of the Year award

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School of Medicine and Population Health