Parker, William, Dr

Dr William Parker

MA, MB, BChir, PhD, PGCertTLHE, DHMSA, MRCS, MRCP

Clinical Medicine, School of Medicine and Population Health

NIHR Clinical Lecturer in Cardiology

w.parker@sheffield.ac.uk
+44 114 226 6159

+44 114 305 2003 (fax)

The Cardiovascular Research Unit (CVRU), Centre for Biomedical Research,, Northern General Hospital

Full contact details

Dr William Parker
Clinical Medicine, School of Medicine and Population Health
The Cardiovascular Research Unit (CVRU), Centre for Biomedical Research,
Northern General Hospital
Herries Road
91ֱ��
S5 7AU

Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I studied Medicine and Pharmacology at the University of Cambridge before returning to my home city of 91ֱ�� to complete the Academic Foundation and Core Medical Training Programmes.

I obtained Membership of the Royal College of Surgeons of England in 2013 and of the Royal Colleges of Physicians of the United Kingdom in 2014.

In 2015, I was appointed Clinical Research Fellow in Cardiology at the University of 91ֱ�� with clinical tenure at the South Yorkshire Cardiothoracic Centre, Northern General Hospital.

In 2018, I was awarded a three-year British Heart Foundation Clinical Training Fellowship completed a PhD under the primary supervision of Professor Rob Storey.

In January 2022, I became National Institute of Health and Care Research (NIHR) Clinical Lecturer in Cardiology. I hold a National Training Number in Cardiology and am Honorary Registrar at the South Yorkshire Cardiothoracic Centre.

Distinctions include a high commendation from the International Aspirin Foundation in 2021, and being ranked the top candidate in the UK at national selection for the cardiology training programme.

Research interests

My main research interest is in improving the quality and safety of drugs used to treat and prevent cardiovascular disease, especially anti-thrombotic therapy for ischaemic heart disease.

Specifically, I am currently investigating the dose-dependent effects of aspirin when used in combination with other antithrombotic agents and how drug regimens can be optimised to augment benefits whilst reducing harm.

I have a wider clinical and academic interest in the pharmacological management of cardiovascular disease and how this can be improved and investigated.

I also study and research the history of medicine and completed the Diploma in the History of Medicine of the Society of Apothecaries of London in 2019, receiving the Maccabean Prize and Osler Lectureship.

Current Projects:

The WILLOW programme: a series of randomised controlled trials investigating the dose-dependent effects of aspirin in combination with other antithrombotic drugs).
Laboratory research into aspirin preparations, metabolism of aspirin and aspirin’s effects on the thromboinflammatory response.
Co-investigator on a wide range of local and multi-centre clinical trials within the Cardiovascular Research Unit.
Research into the history of cardiology and cardiac surgery, particularly early use of cardiopulmonary bypass.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Parker WAE & Storey RF (2019) . European Heart Journal, 40(24), 1971-1974.
Parker WAE, Orme RC, Hanson J, Stokes HM, Bridge CM, Shaw PA, Sumaya W, Thorneycroft K, Petrucci G, Porro B , Judge HM et al (2019) . Platelets, 30(2), 148-157.
Parker WAE, Eriksson N, Becker RC, Voora D, Åkerblom A, Himmelmann A, James SK, Wallentin L & Storey RF (2019) . Platelets, 30(5), 579-588.
Orme RC, Parker WAE, Thomas MR, Judge HM, Baster K, Sumaya W, Morgan KP, McMellon HC, Richardson JD, Grech ED , Wheeldon NM et al (2018) . Circulation, 138(13), 1290-1300.
Sumaya W, Parker W, Fretwell R, Hall I, Barmby D, Richardson J, Iqbal J, Adam Z, Morgan K, Gunn J , Mason A et al (2018) . Thrombosis and Haemostasis, 118(07), 1250-1256.
Parker WA, Bhatt DL, Prats J, Day JRS, Steg PG, Stone GW, Hamm CW, Mahaffey KW, Price MJ, Michael Gibson C , White HD et al (2017) . Thrombosis and Haemostasis, 117(06), 1093-1100.
Parker WAE & Storey RF (2016) . Blood, 128(23), 2595-2597.
Storey RF & Parker WAE (2016) . Circulation, 134(11), 793-796.
Parker WAE & Storey RF (2016) . Heart, 102(10), 783-789.
Maguire JJ, Parker WAE, Foord SM, Bonner TI, Neubig RR & Davenport AP (2009) . Pharmacological Reviews, 61(1), 1-8.
Parker WAE & Storey RF () . European Heart Journal, ehv610-ehv610.

Chapters

Parker W & Storey R (2018) Acute coronary syndromes: Thrombotic Response

All publications

Journal articles

(2023) . British Journal of Cardiology.
Parker WAE, Judge HM, Nelson TA, Elamin N, Williamson G, Shaji N, Middle J, Hanson JA, Bridge CM, Mcmellon HC , Ajjan RA et al (2023) . European Heart Journal, 44(Supplement_2).
Karaban K, Słupik D, Reda A, Gajewska M, Rolek B, Borovac JA, Papakonstantinou PE, Bongiovanni D, Ehrlinder H, Parker WAE , Siniarski A et al (2023) . Current Problems in Cardiology, 102127-102127.
Parker W (2023) . The Annals of Thoracic Surgery.
Storey RF & Parker WAE (2023) . Journal of the American College of Cardiology, 81(19), 1933-1936.
Gardiner EE, Halford GM & Parker WAE (2023) . Platelets, 34(1).
Parker WAE, Angiolillo DJ, Rollini F, Franchi F, Bonaca MP, Bhatt DL, Steg PG, Orme RC, Thomas MR, Judge HM , Sabatine MS et al (2023) . Vascular Pharmacology, 149, 107145-107145.
Siniarski A, Gąsecka A, Borovac JA, Papakonstantinou PE, Bongiovanni D, Ehrlinder H, Giustozzi M, Guerreiro RA & Parker WAE (2023) . Journal of Cardiac Failure.
Varian FL, Parker WAE, Fotheringham J & Storey RF (2023) . Platelets, 34(1).
Elamin N, Ow KW, Parker WAE, Nelson TA, Middle J, Hanson J, Moyle B, Krishnamurthy A, Barmby D, Morgan K , Adam Z et al (2022) . Cardiovascular Research, 118(Supplement_2).
Ariëns RA, Hunt BJ, Agbani EO, Ahnström J, Ahrends R, Alikhan R, Assinger A, Bagoly Z, Balduini A, Barbon E , Barrett CD et al (2022) . Research and Practice in Thrombosis and Haemostasis, 6(5).
Gardiner EE, Halford GM, Harrison P, Parker WAE & Watson SP (2022) . Platelets, 1-2.
Elamin N, Nelson T, Parker W, Varian F, Williamson G, McMellon H, Hanson J, Middle J, Bridge C, Judge HM , Briffa N et al (2022) . Journal of the American College of Cardiology, 79(9), 1094-1094.
Gorog DA, Storey RF, Gurbel PA, Tantry US, Berger JS, Chan MY, Duerschmied D, Smyth SS, Parker WAE, Ajjan RA , Vilahur G et al (2022) . Nature Reviews Cardiology.
Parker WAE, Sagar R, Kurdee Z, Hawkins F, Naseem KM, Grant PJ, Storey RF & Ajjan RA (2021) . Cardiovascular Diabetology, 20(1).
Parker WAE & Storey RF (2021) . Eur Heart J.
Sanderson NC, Parker WAE & Storey RF (2021) . Reviews in Cardiovascular Medicine, 22(2), 373-394.
Nelson TA, Parker WAE, Ghukasyan Lakic T, Westerbergh J, James SK, Siegbahn A, Becker RC, Himmelmann A, Wallentin L & Storey RF (2021) . Platelets, 1-7.
Giustozzi M, Ehrlinder H, Bongiovanni D, Borovac JA, Guerreiro RA, Gąsecka A, Papakonstantinou PE & Parker WAE (2021) . Blood Reviews, 100864-100864.
Gąsecka A, Borovac JA, Guerreiro RA, Giustozzi M, Parker W, Caldeira D & Chiva-Blanch G (2021) . Cardiovascular Drugs and Therapy, 35(2), 215-229.
Parker WAE & Storey RF (2021) . JACC: Basic to Translational Science, 6(3), 219-221.
Hennigan BW, Good R, Adamson C, Parker WAE, Martin L, Anderson L, Campbell M, Serruys PW, Storey RF & Oldroyd KG (2020) . Platelets.
Parker WAE, Gorog DA, Geisler T, Vilahur G, Sibbing D, Rocca B & Storey RF (2020) . European Heart Journal Supplements, 22(Supplement_M), M26-M34.
Parker WAE, Schulte C, Barwari T, Phoenix F, Pearson SM, Mayr M, Grant PJ, Storey RF & Ajjan RA (2020) . Cardiovascular Diabetology, 19(1).
Parker WAE, Parker VL, Parker G & Parker AJ (2020) . The Journal of Laryngology & Otology, 134(10), 848-853.
Ow KW, Parker W, Onwordi E & Storey RF (2020) . Heart, 106(Suppl 2), a41-a41.
Parker WAE (2020) . Transplantation, 104(9), 1769-1771.
Parker WAE & Storey RF (2020) . Expert Opinion on Emerging Drugs.
Storey RF & Parker WAE (2020) . Journal of the American College of Cardiology, 75(3), 301-303.
Parker W & Iqbal J (2020) . Heart International, 14(1), 34-34.
Parker WAE & Storey RF (2019) . European Heart Journal, 40(24), 1971-1974.
Parker WAE, Orme RC, Hanson J, Stokes HM, Bridge CM, Shaw PA, Sumaya W, Thorneycroft K, Petrucci G, Porro B , Judge HM et al (2019) . Platelets, 30(2), 148-157.
Parker WAE, Eriksson N, Becker RC, Voora D, Åkerblom A, Himmelmann A, James SK, Wallentin L & Storey RF (2019) . Platelets, 30(5), 579-588.
Orme RC, Parker WAE, Thomas MR, Judge HM, Baster K, Sumaya W, Morgan KP, McMellon HC, Richardson JD, Grech ED , Wheeldon NM et al (2018) . Circulation, 138(13), 1290-1300.
Sumaya W, Parker W, Fretwell R, Hall I, Barmby D, Richardson J, Iqbal J, Adam Z, Morgan K, Gunn J , Mason A et al (2018) . Thrombosis and Haemostasis, 118(07), 1250-1256.
Parker WAE, Sinha A, Ramshaw HJ, D’Arcy EK, Braidley PC & Al-Mohammad A (2018) . Transplantation, 102(9), e397-e398.
Onwordi ENC, Parker WAE & Storey RF (2018) . Heart, 104(19), 1555-1556.
Parker WAE, Edafe O & Balasubramanian SP (2017) . Pragmatic and Observational Research, 8, 57-67.
Parker WA, Bhatt DL, Prats J, Day JRS, Steg PG, Stone GW, Hamm CW, Mahaffey KW, Price MJ, Michael Gibson C , White HD et al (2017) . Thrombosis and Haemostasis, 117(06), 1093-1100.
Parker WAE & Storey RF (2016) . Blood, 128(23), 2595-2597.
Storey RF & Parker WAE (2016) . Circulation, 134(11), 793-796.
Parker WAE & Storey RF (2016) . Heart, 102(10), 783-789.
Parker W, Parker V, Parker G & Parker A (2014) . International Journal of Audiology, 53(10), 764-769.
Parker WAE & Parker AJ (2009) . Surgery (Oxford), 27(12), 530-534.
Maguire JJ, Parker WAE, Foord SM, Bonner TI, Neubig RR & Davenport AP (2009) . Pharmacological Reviews, 61(1), 1-8.
Parker WAE () . Journal of Medical Biography.
Parker WAE & Storey RF () . British Journal of Pharmacology.
Parker WAE & Storey RF () . Cardiovascular Research.
Papakonstantinou PE, Borovac JA, Gąsecka A, Bongiovanni D, Ehrlinder H, Giustozzi M, Parker WAE & Guerreiro RA () . European Journal of Preventive Cardiology.
Parker WAE & Storey RF () . Heart.
Parker WAE () . Platelets, 1-3.
Parker VL, Parker WAE, Davies HM, Ramshaw HJ, D’Arcy EK, Al-Mohammad A, Mateszko O, Kew FM & Braidley PC () . Surgical Innovation, 155335062093600-155335062093600.
Parker WAE & Storey RF () . Platelets, 1-8.
Ow KW, Parker WAE, Porter MM, Hanson J, Judge HM, Briffa NP, Thomas MR & Storey RF () . Platelets, 1-7.
Parker WAE & Storey RF () . European Heart Journal, ehv610-ehv610.
Sumaya W, Parker WAE, Judge HM, Hall IR, Orme RC, Adam Z, Richardson JD, Rothman AMK, Morgan KP, Gunn JP & Storey RF () . Platelets.
Zwart B, Parker WAE & Storey RF () . Journal of Clinical Medicine, 9(7), 2059-2059.
Parker VL, Winter MC, Whitby E, Parker WAE, Palmer JE, Tidy JA, Pacey AA, Hancock BW & Harrison RF () . British Journal of Cancer.

Chapters

Parker WAE, De Caterina R, Moliterno DJ, Kristensen SD & Storey RF (2023) In De Caterina R, Moliterno DJ & Kristensen SD (Ed.), The ESC Textbook of Thrombosis (pp. 179-C16P154). Oxford University PressOxford
Parker W & Storey R (2018) Acute coronary syndromes: Thrombotic Response

Conference proceedings papers

Elamin N, Nelson TA, Richardson JD, Adam Z, Krishnamurthy A, Iqbal J, Morgan KP, Hall IR, Rothman A, Parker WAE , Storey RF et al (2023) . Acute coronary syndromes & Interventional Cardiology
Shaji N, Elamin N, Nelson T, Varian F, Storey R & Parker W (2022) . Stable IHD/Prevention/Hypertension/Lipids
Parker W, Gosling R, Churton A, Parviz Y, Iqbal J, Heppenstall J, Teare D & Gunn J (2018) . Cardiovascular Research, Vol. 114(suppl_2) (pp S9-S9)
Parker WA, Ramshaw HJ, D'arcy EK, Pickering J, Burger RR, Adatia K, Ogunleye O, Ow KW, Armour SJ, Girach AA , Braidley PC et al (2018) Does deactivation of a site's surgical cardiac transplant program affect the long-term survival of its recipients?. EUROPEAN JOURNAL OF HEART FAILURE, Vol. 20 (pp 447-447)
Parker W, Orme RC, Sumaya W, Hanson J, Stokes H, McMellon H, Shaw P, Judge H & Storey R (2018) . Journal of the American College of Cardiology, Vol. 71(11) (pp A30-A30)
Weng Ow K, Thomas M, Parker W, Judge H & Storey R (2017) . Heart, Vol. 103(Suppl 5) (pp A53.2-A54)

Teaching interests

I am Deputy Co-ordinator of the Phase 1 Cardiovascular Module for the 91ֱ�� MB ChB course and contribute to teaching of medical students from first to final years. I also lecture on the Masters in Cardiovascular Research and Masters in Genomic Medicine programmes. I routinely supervise students completing the BSc in Medical Research.

I was awarded the Postgraduate Certificate in Teaching and Learning for Higher Education from the School of Education at the University of 91ֱ�� in 2021.

I am also passionate about public engagement and have recently devised and delivered sessions for the NHS 70th Anniversary celebrations, 91ֱ�� Ignite Academy, Pecha Kucha foundation and the Millennium Galleries, 91ֱ�� (Leonardo Da Vinci exhibition).

Professional activities and memberships

I am Co-ordinator of the European Society of Cardiology Working Group on Thrombosis Young Researchers, having previously been a Nucleolus member (2018-20) and Vice Co-ordinator (2020-22).

I am incoming Co-Editor-in-Chief of the well-respected journal Platelets, having been a Principal Editor since 2020.

I am Deputy President of the Faculty of the History & Philosophy of Medicine & Pharmacy at the Worshipful Society of Apothecaries of London.

I am a member of the Archives Committee at the British Cardiovascular Society.