Professor Enrico Dall'Ara
PhD
Clinical Medicine, School of Medicine and Population Health
Professor of Musculoskeletal Biomechanics
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+44 114 222 6175
Full contact details
Clinical Medicine, School of Medicine and Population Health
C+31, Pam Liversidge Building; DU19
The Medical School
Beech Hill Road
91直播
S10 2RX
- Profile
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For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I have been Full Professor of Musculoskeletal Biomechanics since 2024.
I hold a PhD from the Vienna University of Biomechanics and a Master in Mechanical Engineering from the University of Bologna.
I am the Director of the Skelet.Al laboratories, the Research Director of the Insigneo Computational Modelling in Medicine research theme, and the Deputy Head of the Integrative MusculoSkeletal Biomechanics (IMSB) Research group.
I am the President of the European Society of Biomechanics
I co-lead the Non-Clinical task force of the Avicenna Alliance.
Current PhD Opportunities:
- Research interests
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My research interests are related to better understanding the properties of musculoskeletal tissues across the space and time scales, by using imaging, experimental and computational methods. In particular, the main goal of my research is to develop and validate subject-specific computational models for the prediction of bone strength, bone remodelling and risk of fracture in healthy subjects and in patients with musculoskeletal diseases, applied to both preclinical and clinical studies.
Research projects:
- Validation of Finite Element models for bone at different dimensional levels
- Development and validation of multiscale models for predicting bone remodelling over time
- Preclinical assessment of osteoarthritis with longitudinal microCT
- Development of Finite Element models to study the outcomes of spine fixation
- Prediction of fracture risk for patients with vertebral metastases with QCT based computational models
- Investigation of the effect of bone metastatic lesions on bone strength
- Investigation of the mechanical properties of subchondral bone from OA patients
- Optimisation of Digital Volume Correlation techniques for measuring deformation in heterogeneous biomaterials
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
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Chapters
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Preprints
- Research group
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PostDocs
PhD Students
- Ms Silvia Dirstaru (PhD student, 1st sup)
- Ms Jingzhi Zhang (PhD student, 1st sup)
- Ms Saira Frage-O'Reilly (PhD student, 1st sup.)
- Mr Robert Roger (PhD student, 1st sup.)
- Ms Fiona Gibson (PhD student, 2nd sup.)
- Mr Zhicheng Lin (PhD student, 2nd sup.)
- Mr Keir Robson (PhD student, 2nd sup.)
- Mr Ryan Cai (PhD student, 2nd sup.)
- Mr Florian Rieger (PhD student at ETH Zurich, co-supervisor; main supervisor Prof Ferguson)
- Mr Albano Malerba (PhD student at University of Liege, co-promotor; main supervisor Prof Ruffoni)
- Mr Vijaysankar Anbalagan (PhD student at University of Leuven, co-promotor; main supervisor Prof van Lenthe)
- Ms Laura Mueller (PhD student at university of Liege, co-promotor; main supervisor Prof Ruffoni)
Research Technicians
- Grants
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- 2024-2029; Dall鈥橝ra E (PI): 鈥淰irtual Mouse and Human Twins for optimising Treatments for Osteoporosis (VHMTs-OP)鈥; EPSRC (EU Guarantee Fund after being Selected for ERC Consolidator grant); ~拢1.74M
- 2023-2028; Dall鈥橝ra E (UoS PI, WP leader), Lacroix D, et al. [Coordinator UniBo]: 鈥淢ETASTRA: Computer-aided effective fracture risk stratification of patients with vertebral metastases for personalised treatment through robust computational models validated in clinical settings鈥; EU HorizonEurope; ~6M euro [~拢773k to 91直播]
- 2022-2027; van Lenthe H, Ruffoni D, Dall鈥橝ra E, Stok K; 鈥淯nderstanding joint health: biomechanical and mechanobiological characterization of the bone-cartilage interface (UNITE)鈥; FNRS and FWO (Belgium, EOS excellence of Science scheme); ~鈧2000k [鈧94.5k to 91直播]
- 2022-2023; Palanca M, Dall鈥橝ra E, Cristofolini L; 2022-2023, 鈥淓ffect of the IVD conditions on the risk of vertebral fracture in metastatic patients鈥; AO Spine Knowledge Forum Associate Research Award, 鈧24k
- 2020-2024; Farage-O鈥橰eilly S, Dall鈥橝ra E; 鈥淢ulti-scale models for the prediction of bone remodelling due to musculoskeletal interventions鈥: PhD studentships EPSRC; ~拢70k
- 2020-2024; Inksson B (PI), Pinna C, Dall'Ara E, Fairclough JPA, Moebus G, Hounslow MJ, Cumming D, Reeves-McLaren N; 鈥淎n X-ray Micro-Computed Tomography Facility with in-situ/in operando testing鈥: EPSRC ; 拢1412k
- 2019-2026; Narracott AJ (PI), Fenner JW, Gunn JP, Clayton RH, Mazza C, Reilly G, Lawford PV, Wild JM, Hose DR, Marzo A, Villa-Uriol MC, Li X, Guo L, Dall'Ara E, Bhattacharya P, Walker DC, Watton P; 鈥淐entre for New Methods in Computational Diagnostics and Personalised Therapy (SANO)鈥: Horizon2020; 鈧2897k
- 2019-2021; Dall鈥橝ra E (PI), Palanca M; 鈥淐omprehensive experimental and computational mechanical characterization of metastatic vertebrae (METASPINE)鈥: Horizon2020, Marie Curie Intra-European Fellowship; 鈧213k
- 2019-2021; Mazza鈥 C (PI), Dall鈥橝ra E, Li X, Battacharia P, Kadirkamanathan V, McCloskey E; 鈥淔rontier Engineering: Progression Grant in Modelling complex and partially identified engineering problems. Application to the musculoskeletal system (MULTISIM2)鈥: Progression Grant EPSRC; 拢758k
- 2019-2020; Dall鈥橝ra E (PI); 鈥淓quipment for Mouse gait lab鈥: EPSRC ECR Capital Enhancement Programme 2018
- 2018-2022; Reilly G (PI), Mazza鈥 C, Lacroix D, Claeyssen F, Guo L, Dall鈥橝ra E; 鈥淪PINe: Numerical and Experimental Repair strategies鈥: Horizon2020 European program, Initial Training Network; 拢476k
- 2017-2020; Dall鈥橝ra E (PI), Bellantuono I, Viceconti M; 鈥淚n silico approaches for preclinical assessment of bone changes in osteoporosis and osteoarthritis studies鈥: National Centre for replacement, refinement and reduction of animal use in research; 拢353k
- 2017-2019; Bellantuono I (PI), Dall鈥橝ra E; 鈥淭argeting mechanisms of ageing to maintain musculoskeletal health鈥: Biological and Biotechnological Sciences Research Council; 拢261k
- 2017-2019; Dall鈥橝ra E (PI); 鈥淣ovel Assessment of the Osteoarthritic Hip Subchondral Bone: a Combined Experimental and Computational Investigation鈥: Engineering and Physical Sciences Research Council; 拢101k
- 2015-2016; Dall鈥橝ra E (PI); 鈥淢ultiscale characterization of osteoarthritic subchondral bone: combination of microCT, elastic registration and microindentation鈥: Royal Society research grant; 拢15k
- 2016-2019; Dall鈥橝ra E (PI), Hose R, Lawford P; 鈥淎ssessment of bone growth in preclinical studies with Kalman filtering鈥: EPSRC PhD scholarship; 拢65k
- 2015-2018; Dall鈥橝ra E (PI), Viceconti M; 鈥淧rediction of the risk of vertebral fracture in patients with metastatic lesions as a tool for more effective patients鈥 management鈥: 91直播 Hospitals Charity; 拢65k
- 2013-2015; Dall鈥橝ra E (Fellow), Viceconti M; 鈥淢ethodologically and Accurate modelling of bone鈥: FP7, Marie Curie Intra-European Fellowship; 鈧222k
- Teaching interests
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I teach in the Computational Biomechanics of the Musculoskeletal System (MEC457, BIE6433).
I give invited lectures in different modules in engineering.
- Professional activities and memberships
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- Director of the SkeletAl laboratory since 2020
- Research Director Insigneo "Computational Modelling in Medicine" research theme since 2021
- Head of the Integrative Musculoskeletal Biomechanics (IMSB) group 2022-2024
- Member of Mellanby Centre for Musculoskeletal Research Executive Committee since 2021
- President of the European Society of Biomechanics since 2024
- Council member for the European Society of Biomechanics since 2018
- President of the UK chapter of the Virtual Physiological Human Institute 2018-2024
- Deputy chair of the Working Group 3 of the Bone Metastases Group of the National Cancer Research Institute in 2023
- Editorial Board member of the Journal of Mechanical Behaviour of Biomedical Materials since 2019
- Associate Editor for Frontiers in Bioengineering and Biotechnology (Biomechanics) since 2022
- Member of the ESB since 2008, BRS since 2014, ECTS since 2015 and ORS since 2017
- Reviewer for national and international funders
- Reviewer for the major journals in the field of biomechanics and bone research