Staton, Carolyn, Dr

Dr Carolyn Staton

PhD, MBiochem, SFHEA

Clinical Medicine, School of Medicine and Population Health

Senior Lecturer

c.a.staton@sheffield.ac.uk
+44 114 215 9063

The Medical School

Full contact details

Dr Carolyn Staton
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
91ֱ��
S10 2RX

Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I joined the University in 1997 as a PhD student. During the course of my PhD, I discovered a number of novel anti-angiogenic agents which were patented by the University of 91ֱ�� and led to me being given the AACR – Novartis Scholar In Training Award (2000) and the BACR Translational Research Award (2005) - both in open competition.

In 2004 I was appointed to a lectureship and was awarded the Certificate in Learning and Teaching in 2009. In 2013 I designed and established the MSc(Res) in Translational Oncology and in 2016 I became a Senior Fellow of the Higher Education Academy and Senior Lecturer. I was the departmental director of learning and teaching for the Department of Oncology & Metabolism from 2018-2021.

I am currently the Director of Intercalated Studies, the Deputy Director of the Personal Academic Tutoring scheme, the medical school Disability Liaison officer for PGT, and the History of Medicine Lead. I am also a member of the University Discipline Committee.

Research interests

My current research interests are student perceptions and decision-making processes around intercalation.

Collaborative research with colleagues in 91ֱ�� also includes investigations into incidentaloma in modern medicine, the challenges and potential solutions.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Cole-Healy Z, Vergani P, Hunter K, Brown NJ, Reed MWR & Staton CA (2015) . Experimental and Molecular Pathology, 99(1), 19-24.
Young RJ, Woll PJ, Staton CA, Reed MWR & Brown NJ (2014) . Cancer Chemother Pharmacol, 73(2), 259-270.
Staton CA, Koay I, Wu JM, Hoh L, Reed MWR & Brown NJ (2013) . Histopathology, 62(6), 908-915.
Wu JM & Staton CA (2012) . Expert Opin Drug Discov, 7(8), 723-743.
Wild JRL, Staton CA, Chapple K & Corfe BM (2012) . Int J Exp Pathol, 93(2), 81-103.
Hsu Y-P, Staton CA, Cross N & Buttle DJ (2012) . Int J Exp Pathol, 93(1), 70-77.
Mackinder MA, Evans CA, Chowdry J, Staton CA & Corfe BM (2012) . Cancer Biomark, 12(2), 49-64.
Valluru M, Staton CA, Reed MWR & Brown NJ (2011) . Front Physiol, 2, 89.
Staton CA, Shaw LA, Valluru M, Hoh L, Koay I, Cross SS, Reed MW & Brown NJ (2011) . Histopathology, 59(2), 274-282.
Valluru M, Brown NJ, Cross SS, Reed MWR & Staton CA (2011) . Br J Dermatol, 165(1), 221-224.
Yu DCW, Bury JP, Tiernan J, Waby JS, Staton CA & Corfe BM (2011) . Mol Cancer, 10, 27.
Bluff JE, Amarzguioui M, Slattery J, Reed MWR, Brown NJ & Staton CA (2011) . Breast Cancer Res Treat, 128(3), 691-701.
Yu DCW, Waby JS, Chirakkal H, Staton CA & Corfe BM (2010) . Mol Cancer, 9, 276.
Staton CA, Valluru M, Hoh L, Reed MWR & Brown NJ (2010) . Br J Dermatol, 163(5), 920-927.
Kumar I, Staton CA, Cross SS, Reed MWR & Brown NJ (2009) . Br J Surg, 96(12), 1484-1491.
Bluff JE, Menakuru SR, Cross SS, Higham SE, Balasubramanian SP, Brown NJ, Reed MW & Staton CA (2009) . Br J Cancer, 101(4), 666-672.
Staton CA, Reed MWR & Brown NJ (2009) . Int J Exp Pathol, 90(3), 195-221.

All publications

Books

Staton C, Lewis CE & Bicknell R (2007) Angiogenesis Assays: A Critical Appraisal of Current Techniques. Wiley-Blackwell.

Journal articles

Kapoore RV, Coyle R, Staton CA, Brown NJ & Vaidyanathan S (2017) . Analyst, 142(11), 2038-2049.
Kapoore RV, Coyle R, Staton CA, Brown NJ & Vaidyanathan S (2015) . Metabolomics, 11(6), 1743-1755.
Cole-Healy Z, Vergani P, Hunter K, Brown NJ, Reed MWR & Staton CA (2015) . Experimental and Molecular Pathology, 99(1), 19-24.
Young RJ, Woll PJ, Staton CA, Reed MWR & Brown NJ (2014) . Cancer Chemother Pharmacol, 73(2), 259-270.
Wild J, Gunarwardene A, Staton C, Chapple K & Corfe B (2013) . International Journal of Surgery, 11(8), 600-600.
Narramore R, Wild J, Corfe B, Staton C, Yu D & Chapple K (2013) . International Journal of Surgery, 11(8), 624-624.
Staton CA, Koay I, Wu JM, Hoh L, Reed MWR & Brown NJ (2013) . Histopathology, 62(6), 908-915.
Wu JM & Staton CA (2012) . Expert Opin Drug Discov, 7(8), 723-743.
Wild JRL, Staton CA, Chapple K & Corfe BM (2012) . Int J Exp Pathol, 93(2), 81-103.
Hsu Y-P, Staton CA, Cross N & Buttle DJ (2012) . Int J Exp Pathol, 93(1), 70-77.
Mackinder MA, Evans CA, Chowdry J, Staton CA & Corfe BM (2012) . Cancer Biomark, 12(2), 49-64.
Staton CA (2011) . Biochem Soc Trans, 39(6), 1565-1570.
Valluru M, Staton CA, Reed MWR & Brown NJ (2011) . Front Physiol, 2, 89.
Staton CA, Hoh L, Baldwin A, Shaw L, Globe J, Cross SS, Reed MW & Brown NJ (2011) . Histopathology, 59(2), 256-263.
Staton CA, Shaw LA, Valluru M, Hoh L, Koay I, Cross SS, Reed MW & Brown NJ (2011) . Histopathology, 59(2), 274-282.
Young RJ, Brown NJ, Staton CA, Reed MW & Woll PJ (2011) Functional studies in two angiosarcoma cell lines.. J Clin Oncol, 29(15_suppl), e20511.
Gunawardene AR, Corfe BM & Staton CA (2011) . Int J Exp Pathol, 92(4), 219-231.
Valluru M, Brown NJ, Cross SS, Reed MWR & Staton CA (2011) . Br J Dermatol, 165(1), 221-224.
Yu DCW, Bury JP, Tiernan J, Waby JS, Staton CA & Corfe BM (2011) . Mol Cancer, 10, 27.
Bluff JE, Amarzguioui M, Slattery J, Reed MWR, Brown NJ & Staton CA (2011) . Breast Cancer Res Treat, 128(3), 691-701.
Krajewska E, Lewis C, Staton C, MacGowan A & MacNeil S (2011) . J Tissue Eng Regen Med, 5(5), 363-374.
Yu DCW, Waby JS, Chirakkal H, Staton CA & Corfe BM (2010) . Mol Cancer, 9, 276.
Staton CA, Valluru M, Hoh L, Reed MWR & Brown NJ (2010) . Br J Dermatol, 163(5), 920-927.
Krajewska E, Lewis CE, Chen Y-Y, Welford A, Tazzyman S & Staton CA (2010) . Br J Cancer, 102(3), 594-601.
Kumar I, Staton CA, Cross SS, Reed MWR & Brown NJ (2009) . Br J Surg, 96(12), 1484-1491.
Staton CA, Brown NJ & Reed MWR (2009) . EXPERT OPIN DRUG DIS, 4(9), 961-979.
Bluff JE, Menakuru SR, Cross SS, Higham SE, Balasubramanian SP, Brown NJ, Reed MW & Staton CA (2009) . Br J Cancer, 101(4), 666-672.
Staton CA, Reed MWR & Brown NJ (2009) . Int J Exp Pathol, 90(3), 195-221.
Menakuru SR, Brown NJ, Staton CA & Reed MWR (2008) . Br J Cancer, 99(12), 1961-1966.
Kumar I, Balasubraminian S, Staton C, Brown N & Reed M (2008) . European Journal of Surgical Oncology (EJSO), 34(10), 1194-1194.
Bluff JE, Brown NJ, Reed MWR & Staton CA (2008) . Breast Cancer Res, 10(2), 204.
Staton CA, Chetwood ASA, Cameron IC, Cross SS, Brown NJ & Reed MWR (2007) . Gut, 56(10), 1426-1432.
Staton CA, Lewis C & Bicknell R (2007) . Angiogenesis Assays: A Critical Appraisal of Current Techniques.
Staton CA, Kumar I, Reed MWR & Brown NJ (2007) . J Pathol, 212(3), 237-248.
Staton CA, Stribbling SM, García-Echeverría C, Bury JP, Tazzyman S, Lewis CE & Brown NJ (2007) . J Thromb Haemost, 5(4), 846-854.
Staton CA & Lewis CE (2005) . J Cell Mol Med, 9(2), 286-302.
Staton CA, Stribbling SM, Tazzyman S, Hughes R, Brown NJ & Lewis CE (2004) . Int J Exp Pathol, 85(5), 233-248.
Staton CA, Brown NJ, Rodgers G, Corke KP, Tazzyman S, Underwood JCE & Lewis CE (2004) . Microcirculation, 11(6), 531-532.
Staton CA, Brown NJ, Rodgers GR, Corke KP, Tazzyman S, Underwood JCE & Lewis CE (2004) . Blood, 103(2), 601-606.
Staton CA, Brown NJ & Lewis CE (2003) . Expert Opin Biol Ther, 3(7), 1105-1120.
Brown NJ, Staton CA, Rodgers GR, Corke KP, Underwood JCE & Lewis CE (2002) . Br J Cancer, 86(11), 1813-1816.
Bootle-Wilbraham CA, Tazzyman S, Thompson WD, Stirk CM & Lewis CE (2001) . Angiogenesis, 4(4), 269-275.
Bootle-Wilbraham CA, Tazzyman S, Marshall JM & Lewis CE (2000) Fibrinogen E-fragment inhibits the migration and tubule formation of human dermal microvascular endothelial cells in vitro.. Cancer Res, 60(17), 4719-4724.
Jeziore-Sassoon Y, Hamblin PA, Bootle-Wilbraham CA, Poole PS & Armitage JP (1998) . Microbiology, 144 ( Pt 1), 229-239.

Chapters

Staton CA & Smith EJ (2006) Tubule Formation Assays In Staton C, Lewis CE & Bicknell R (Ed.), Angiogenesis Assays: A Critical Appraisal of Current Techniques (pp. 65-88). Wiley-Blackwell
Staton CA & Lewis CE (2006) Alphastatin: a pluripotent inhibitor of activated endothelial cells In Siemann DW (Ed.), Vascular-targeted therapies in oncology (pp. 205-220). Wiley-Blackwell
Staton CA & Lewis CE (2005) Haemostatic Regulators as drug targets in tumour angiogenesis In Weber GF (Ed.), Cancer therapy (pp. 187-220). Taylor & Francis
Staton CA, Brown NJ & Lewis CE (2004) Effects of fibrinogen and associated peptide fragments on the activation of human endothelial cells by VEGF in vitro In Harmey JH (Ed.), VEGF and Cancer (pp. 117-132). Springer

Conference proceedings papers

Wild JRL, Staton CA, Chapple KS & Corfe BM (2013) Comparison and Optimisation of a strategy to isolate a single cell population of epithelial cells from the crypt compartment of the murine colon. BRITISH JOURNAL OF SURGERY, Vol. 100 (pp 99-99)
Wild JRL, Gunawardene AR, Staton CA, Chapple KS & Corfe BM (2013) Neuropilin-1 expression in the normal colon is enteroendocrine-like. BRITISH JOURNAL OF SURGERY, Vol. 100 (pp 123-123)
Bury JP, Riley S, Evans CA, Williams EA, Staton CA, Murabito E, Smallbone K & Corfe BM (2012) Why do Patients get Metachronous Colorectal Adenomas?. JOURNAL OF PATHOLOGY, Vol. 228 (pp S3-S3)
Wild JRL, Khan AQ, Li NX, Staton C, Chapple K & Corfe BM (2012) Neuropilin-1: A predictor of early carcinogenesis in the colonic epithelium. BRITISH JOURNAL OF SURGERY, Vol. 99 (pp 24-24)
Khan AQ, Wild J, Nai X, Brown S, Staton C, Brown S & Corfe B (2012) Faecal butyrate levels have different effect on cancer and adenoma tissues: Suggestion of early beneficial role of butyrate during carcinogenesis. BRITISH JOURNAL OF SURGERY, Vol. 99 (pp 29-29)
Young R, Woll PJ, Staton CA, Reed MW & Brown NJ (2011) Targeting VEGF in Human Angiosarcoma Cell Lines in Vitro. EUROPEAN JOURNAL OF CANCER, Vol. 47 (pp S665-S665)
Young RJ, Tin A, Brown NJ, Staton C, Lee SM, Jital M & Woll P (2011) SERUM BIOMARKERS IN LUNG CANCER PATIENTS FROM TWO CLINICAL TRIALS OF CHEMOTHERAPY WITH OR WITHOUT THALIDOMIDE. J THORAC ONCOL, Vol. 6(6) (pp S1058-S1059)
Young RJ, Brown NJ, Staton CA, Reed MW & Woll PJ (2011) . JOURNAL OF CLINICAL ONCOLOGY, Vol. 29(15)
Lunj S, Staton CA, Holen I, Ballmer-Hofer K, Reed MW & Brown NJ (2011) . Tumor Biology
Hsu YP, Staton CA & Buttle DJ (2010) ADAMTS-4 may regulate VEGF-stimulated angiogenesis. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 91(6) (pp A32-A33)
Hsu YP, Staton CA & Buttle DJ (2010) Molecular interactions of ADAMTS-4 in the VEGFR2 signalling complex. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 91(2) (pp A30-A30)
Hsu YP, Staton CA & Buttle DJ (2009) The molecular interactions involved in VEGF-induced signalling pathways. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 90(2) (pp A114-A114)
Bluff JE, Cross SS, Brown NJ, Reed MW & Staton CA (2008) . BREAST CANCER RESEARCH, Vol. 10 (pp S24-S24)
Staton CA, Yang Z, Reed MWR & Brown NJ (2008) . BREAST CANCER RESEARCH, Vol. 10 (pp S38-S38)

Teaching interests: I am passionate about student support and welfare and am the Disability Liaison Officer for the Medical School PGT students and the deputy academic director of the Personal Academic Tutor scheme (MBChB) and an associate director of student affairs. I am a personal academic tutor and/or mentor for undergraduate medical students, PGT and PGR students in the Medical school and was nominated for Best Academic Mentor in the Annual Academic Awards 2018.

Teaching activities

I am the Director of Intercalation studies and am the course lead of the BSc Medical Sciences Research and the BSc Medical Sciences (Surgery). I am also the History of Medicine SSC lead, the deputy ILA lead (phase 1 and 2), and involved in physiology teaching for first-year MBChB students as well as assessment setting and quality assurance.

I lead the Tumour Microenvironment and Literature Review modules on the MSc(Res) in Translational Oncology course and teach on the MSc in Molecular Medicine course.

Professional activities and memberships

Senior Fellow of the Higher Education Academy
Director of Intercalated Studies
Disability Liaison Officer for Medical School PGT
Academic Lead – BSc Medical Sciences Research
Academic Lead – BSc Medical Sciences (Surgery)
Academic Lead – History of Medicine SSC
Deputy Academic Director of the Personal Academic Tutor scheme for MBChB
Honorary Treasurer – British Microcirculation Society (2016-2021)
External Examiner at the University of Nottingham & Hull