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Research Supervisor Details

This page provides additional information about our research supervisors to help you choose an appropriate supervisor. You can either browser supervisors by school or search for them. Most supervisors also have a personal webpage where you can find out more about them. If that is not listed here you can also try searching our main pages: search our site

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Dr David Andrew
d.andrew@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry
Mr Simon Atkins
s.atkins@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry
Professor Sarah Baker
s.r.baker@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

My research interests centre on the application of psychological theories, methods and techniques to address key questions in oral health and the field of dentistry. This includes research in a range of areas including: clinical, psychological and social determinants and impacts of oral health; development and evaluation of person-centred outcome measures for oral health including, dentine hypersensitivity, dry mouth, dentures, and gum health; oral health inequalities and barriers to dental care; life-course approaches to oral health; barriers and facilitators to implementing research findings in dental practice; systems science approaches to Wicked Problems in oral health; critical dental public health and social oral epidemiology.

 


Dr Lynne Bingle
l.bingle@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

My long-standing research interests have been focused on the role and regulation of epithelial secretory proteins. This work has principally involved the study of the airway epithelium, through the use of 3D in vitro model systems, but more recently has expanded to include the oral and nasal mucosa and the epithelium of the middle ear. My specific interests have focused on the fields of innate immunity, host defence and tumour biology.

I have also recently started to investigate the potential of using my tissue culture expertise to develop in vitro models of human salivary glands from fresh human tissue. We are now routinely isolating cells from human sublingual glands and are currently characterising cell phenotype under different culture conditions. The mid-term aim is to use these models to begin to elucidate the initial stages of salivary gland diseases such as Sjogren’s syndrome and salivary gland tumours.

 

 

Professor Fiona Boissonade
f.boissonade@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

I have a major research interest in the mechanisms of altered neuronal excitability that occur under the pathological conditions of nerve injury and inflammation, and which contribute to the development of chronic pain, including that in the oro–facial region. Much of this research has been done at the academic–industrial interface. Collaborations with GSK, Pfizer and Eli Lilly have funded a wide range of pre-clinical translational studies, using pre-clinical models and human tissues to identify and validate a range of regulators of neuronal excitability as potential targets for the development of novel analgesics and anti-inflammatory mediators.

Other research projects are directed towards improvement of nerve regeneration. This work investigates methods of improving nerve repair through the use of a range of anti-inflammatory and anti-scarring agents, and includes collaboration with the Department of Engineering Materials at the University of 91直播 to develop bioengineered conduits to enhance nerve regeneration. In other projects I collaborate with the 91直播 Institute for Translational Neuroscience (SITraN) investigating the role of chemokines in CNS disease.
I also have a significant research interest in neural–immune interactions and their role in the development of disease. I have a number of pilot projects underway in this field investigating neural interactions in the generation of cancer pain and tumour progression.

 

 

Dr Robert Bolt

Personal Webpage

School of Clinical Dentistry
Professor Helen Colley
h.colley@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

 

My eresearch interests are in epithelial cell biology and tissue engineering, in particular the construction and use of 3D multi-cellular models. Within my laboratory we have successfully developed and characterised advanced full thickness constructs to model human skin and oral mucosa to assist in understanding the biology in health and disease.  Using these systems, my current research focuses on the development of the novel therapeutics and drug delivery mechanisms for epithelial drug delivery. 

 

 

Dr Milena De Felice
m.defelice@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Our research aim is to use and further develop neurobiological and neuropharmacological approaches (including MRI imaging, in vivo, neurochemistry, molecular and electrophysiology) to study altered neuronal excitability and activity in the central nervous system using in vitro and in vivo preclinical models of human disorders. We particularly focus on neurological conditions such as migraine and stroke and associated comorbidities (i.e. cardiovascular and psychiatric disorders, inflammatory conditions) to identify the molecular changes that ultimately contribute to the development of chronic pain in these conditions, with the potential of offering novel targets for the development of new therapeutics.


Dr Claire Elcock
c.elcock@sheffield.ac.uk

School of Clinical Dentistry

Research interests

Oral clinical phenotyping, involving the accurate measurement of oral parameters using image analysis.


Normal and abnormal oral growth and development, including investigations into anomalies of tooth number, size, form and structure.


Quantification of dental plaque and periodontal disease.


Child protection, children and young people's oral health, oral neuroscience.

 

 

Professor Barry Gibson
b.j.gibson@sheffield.ac.uk


School of Clinical Dentistry

Research interests

 

Research interests include sociology and public health, giving patients' voices in their care and exploring the relationship between consumption and health. My current work explores the impact of tooth loss on oral health related quality of life and wellbeing. This work links with my growing interest in the intersections between sociology, public health  and consumption. I have students examining the social organisation of ill health drawing on a range of social theories including social practice theory, critical discourse analysis, ethnography and grounded theory.

In relation to oral health and dentistry I continue to develop my interest in the sociology of oral health and healthcare by examining the embodied experience of dental care. This involves a sustained analysis of the work of dentists and patients in maintaining oral health using ethnography (digital and observational) and qualitative research methods.

 

 

Miss Fiona Gilchrist
f.gilchrist@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

I joined the University of 91直播 in 2007 as a Lecturer in Paediatric Dentistry. I completed the first part of my specialist training in Edinburgh in 2006 and then worked as a Senior Registrar at the Royal Children's Hospital in Melbourne for six months before moving to 91直播. I completed my NHS consultant training in 2009. I was awarded an NIHR Doctoral Research Fellowship in 2012 and completed my PhD in 2015. In 2015 I was appointed Senior Lecturer and took up the role as the Lead Paediatric Dentist for the Trent Regional Cleft Network.

During my PhD I developed a measure of oral health-related quality of life for children with dental caries (CARIES-QC). This was developed with children and is being used in clinical trials to determine the impact of interventions for caries and has been translated into a number of languages. My current research interests are focussed around the routine use of patient-reported outcome measures for children and young people including those with cleft lip and palate. In particular, I'm interested in investigating the use of electronic methods for delivery of PROMs to paediatric patients and how the information generated by these can aid clinicians in diagnosis and treatment planning.

 

 

Dr Luke Green
l.r.green@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Bacterial infections cause a diverse range of disease ranging from superficial skin infections to periodontitis to severe infections such as sepsis and meningitis. This coupled with rising antimicrobial resistance have led to increasing burdens of infection and are therefore a significant health concern worldwide. Bacterial adhesion to host cells is essential for both colonisation and infection. New therapies to prevent adhesion could significantly decrease disease and reduce the burden of antibiotic usage.

We have identified a superfamily of proteins on host cells which appear to control bacterial adherence to epithelial cells. These proteins, the tetraspanins, do not act as receptors but organise and cluster hijacked host proteins into 'adhesion platforms' to allow efficient adherence and entry of bacteria to cells. Blockade of these proteins leads to a significant reduction in bacterial adherence of many Gram negative and Gram positive bacteria. Using a variety of techniques we have identified members of these adhesion platforms and new ways to inhibit their function during infection. Furthermore, we investigate changes to the composition of both bacterial membrane proteins and host adhesion platforms during tetraspanin-mediated infection utilising a number of bacteria as models.

We are also interested in the importance of the bacterial microbiome in humans and how dysbiosis of this flora can affect various diseases ranging from skin afflictions to cancer. We currently run a number of studies which utilise Oxford Nanopore Technology sequencers to delineate the microbiome.

 

 

Professor Paul Hatton
paul.hatton@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

 

Research interests

Professor Hatton has interests in biomaterials, medical devices and tissue engineering for clinical applications in human skeletal tissues. The five major themes for his research are (1) the development of bioactive glasses and ceramics for mineralised tissue repair, (2) glass-ionomer bone cements, (3) In vitro evaluation of biocompatibility, and (4) Cartilage and bone tissue engineering on biomaterial scaffolds. He is also active more broadly in the promotion of academic-industrial collaboration and technology transfer in the orthopaedic, craniofacial and dental material sectors. 

 

 

Dr Stuart Hunt
s.hunt@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Head and neck cancer (HNC) is the 8th most common cancer in the UK. There are approximately 12,400 new HNC cases diagnosed in the UK each year and over 4,000 HNC-related deaths annually (Cancer Research UK). The Hunt Lab focuses on the role of extracellular vesicles (and other extracellular particles) in HNC. We research the mechanisms regulating their production (biogenesis) and how they mediate intercellular communication within the tumour microenvironment. We also explore how they could be exploited as a source of diagnostic/prognostic biomarkers and as novel therapeutic targets for head and neck cancer. Working in a clinical department, we have access to ex vivo patient samples and a wide range of HNC cell lines for in vitro studies.


Professor Ali Khurram
s.a.khurram@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

 

I am a Professor and Honorary Consultant in Oral and Maxillofacial Pathology. Prior to that, I worked as a Senior Clinical Lecturer (2016-2022) and as a NIHR Academic Clinical Lecturer/ Honorary Specialist Registrar (2011-2016) at the University of 91直播.

I have a strong interest and am actively involved in research and teaching (undergraduate, postgraduate, clinical) as well as diagnostic oral, maxillofacial and head and neck pathology. I am the founder and Lead of the working with a team of researchers and clinicians on various aspects of head and neck cancer diagnosis and prognosis prediction. In addition to local research projects, my group is working with a wide range of collaborators and funders across the world.

I am passionate about raising the profile of Pathology as a specialty and raising awareness of head and neck cancers. I work closely with a number of patient groups and charities and am a .

 

 

Professor Daniel Lambert
D.W.Lambert@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

The interests of our research group fall in three broad interlinking areas, all of which seek to identify novel opportunities to improve quality of life.

Molecular mechanisms of cell:cell communication in ageing and cancer 

The behaviour of all cells is dictated by the signals derived from the surrounding microenvironment. In ageing and cancer, these signals may become corrupted by changes in surrounding cells, or by biomechanical or chemical changes to the extracellular matrix (ECM). A major focus of our work is to identify the mechanisms by which these signals, become corrupted. We are particularly interested in the role of signals derived from senescent cells, particularly the major cell type of connective tissue, fibroblasts, which accumulate with age and in several diseases, including cancer.  These signals include proteins, RNA (particularly non-coding RNA), DNA and extracellular vesicles.

Spatial analysis of the tissue microenviroment

In order to understand the mechanisms outlined above, we need to better understand the changes that happen within tissue in ageing and cancer. We are applying cutting edge spatial 'omics' techniques to understand, at an unprecedented level of resolution, the changes occuring in the phenotype of cells in aged and diseased tissue.  This will allow us to much more accurately model changes in the tissue microenvironment and identify potential new, individualised, therapeutic opportunities. We are also working closely with biomaterials scientists to use this information to use materials to mimic the tissue microenvironment, allowing us to accurately model the processes occuring in the body and also develop new ways to reverse disease-associated changes and regenerate damaged tissue.

Biomarker discovery 

The diagnosis and monitoring of many diseases, including cancer, requires painful collection of tissue. We are working closely with world-leading physical scientists to develop new ways to detect 'biomarkers' of cancer in blood and saliva, allowing non-invasive or entirely painless disease diagnosis and monitoring. These approaches include nanoplasmonics and other methods not routinely used for biological applications, but with the promise to revolutionalise disease sensing. We are also applying these technologies to the analysis of senescence, to allow accurate determination of biological age and support the development of drugs designed to reduce the health impacts of ageing.

 

 

Professor Zoe Marshman
z.marshman@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Professor Marshman’s main interest is child-centred dental research to improve the oral health and treatment experiences of children and their families. She has experience of leading large multi-centred randomised controlled trials, conducting qualitative research and the development of child oral health interventions. Professor Marshman has published widely on topics including oral health-related quality of life, oral health promotion and dental anxiety.

 

 

 

 

 

Professor Nicolas Martin
n.martin@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Synthesis and application of nano-particulate materials for dental applications.

The application of nucleating agents for the remineralisation of dentine

Integrity of structurally compromised restored teeth as compound systems

Optimisation of ceramic crown-tooth compound systems

Development and characterisation of novel restorative systems.

Remote digital communication for the provision of health care in dentistry

Development of L&T in restorative dentistry

Clinical evaluation of restorative systems

Professor Cheryl Miller
c.a.miller@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

My research interests are varied, interdisciplinary and lie within the field of materials for biomedical and dental applications. My research focuses on the design, fabrication and characterisation of novel glasses, ceramics and composites for dental and medical applications. Much of this research is in collaboration with Engineering Materials (UoS), Imperial College London, Chubu University, Japan and Sao Paulo University, Brazil. My research has also progressed to the production of custom prostheses using novel production methods and advanced manufacturing techniques such as additive manufacture, Hot-Isostatic-Pressing, Spark-Laser-Sintering, freeze-casting, laser machining and electro-spinning. In addition, due to my involvement in the MMedSci in Dental Implantology, I also supervise projects in the area of dental implantology.

My research is progressing more towards knowledge and technology transfer, hence my industrial collaborations are widening and increasing, presently these include Ceramisys Ltd (a SME manufacturing and distributing bone augmentation materials); Fluidinova (a SME manufacturer of nanoceramics); Primequal (a SME specialising in development of medical devices); neotherix (a regenerative medicine SME specialising in novel bioresorbable scaffolds); CERAM (materials testing, analysis and consultancy); JRI (a manufacturer of orthopaedic implants and surgical instrumentation); Nobel Biocare (a world leader in innovative restorative and aesthetic dental solutions); Dentsply (a global leading manufacturer and distributer of high quality dental product) and GlaxoSmithKline (one of the world's leading research-based pharmaceutical and healthcare companies).

 

 

Professor Craig Murdoch
c.murdoch@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Main interests are centred on oral epithelial biology, the mechanisms of oral disease pathogenesis and development of new treatment strategies. I am particularly interested in how immune cells are recruited to and act at diseased oral sites and how they interact with other cells/microbes within the local microenvironment. My group has developed novel tissue engineered in vitro models of both healthy and diseased oral mucosa (and skin) to investigate disease processes. I have a long-standing track record of utilising these in vitro 3D engineered tissues as well as zebrafish larvae as direct replacements for animal models and have used these to study the role of oral microorganisms in mucosal and systemic disease. I’m also involved in projects aimed at fabricating oral patches and microneedles made from mucoadhesive polymers for oral mucosal drug delivery. Here we have produced electrospun patches to deliver small molecule drugs such as glucocorticoids, analgesics, antifungals and larger molecules such as antibodies and mRNA for vaccine delivery. I also work within a consortium of researchers developing electrical impedance as a form of non-invasive early diagnostics for the detection and management of oral premalignant disorders.

Current projects include:

  • Novel forms of oral mucoadhesive drug and vaccine delivery and the role of xenobiotic metabolising enzymes in the oral mucosa.
  • Development of tissue engineered oral mucosal and skin model - atopic dermatitis, oral lichen planus
  • Host-pathogen interactions at the mucosal surface.
  • Role of innate immune cells in head and neck cancer.
  • Use of zebrafish to examine the role of oral microbes in systemic disease.
Dr Ilida Ortega Asencio
i.ortega@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

 

Research interests

Dr. Ilida Ortega Asencio specialises in biomaterial development and the utilisation of advanced biofabrication techniques, such as electrospinning and 3D-printing. Her primary research involves the manufacturing, characterization, and in vitro testing of biomaterial devices tailored for tissue engineering applications. With a comprehensive understanding of materials for soft tissue regeneration, particularly in skin and cornea, she has collaborated internationally with renowned organizations and networks, including LV Prasad Eye Institute and European Consortiums such as COST NetskinModels.

Dr. Ortega's interests lie in the design of 3D synthetic niche-like microenvironments to explore cell responses, as well as in the creation of smart electrospun materials for targeted drug delivery. Notably, she has explored bone tissue regeneration approaches through a Chinese Government-funded scholarship, investigating novel strategies to address problems at the bone-tendon interface. She has also secured funding from the Advanced Biomedical Materials CDT (Manchester/91直播) to develop a bilayer skin construct that incorporates topographical cues resembling the rete ridges in the skin.

Dr. Ortega is renowned for her contributions to dental materials research, characterized by her close collaboration with clinicians to develop cutting-edge approaches to dental materials design. Recently, Dr. Ortega has developed a keen interest in exploring sustainability aspects related to her research, particularly in conjunction with CAD-CAM approaches. She has secured knowledge-exchange funding for a collaborative project with Dentsply Sirona focused on life cycle analysis (LCA). Overall, Dr. Ortega's work in biomaterial development exemplifies a bench-to-clinic approach, demonstrating her dedication to advancing regenerative medicine and ultimately improving patient outcomes.

 

 

Dr Thomas Paterson
t.paterson@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

Dr Thomas Paterson is a Lecturer in the School of Clinical Dentistry at the University of 91直播, where he combines his expertise in materials science with the field of bioelectronics to drive innovations in healthcare. His research primarily develops implantable and wearable bioelectronic devices that improve diagnostics and treatments across various medical applications. These devices span a wide array of applications, from epilepsy treatment and soft electrode manufacturing to wound healing and dental health monitoring, aiming to address complex healthcare challenges through technology.

Throughout his career, Dr Paterson has developed a particular interest in additive manufacturing, hydrogel engineering, biosignal recording and antimicrobial materials. These interests have translated into several ongoing projects, including developing conductive and elastic materials for wearable diagnostics, conductive electrospun sensors for jaw movement tracking, and exploring cellular mechanisms underpinning wound healing under variable pressure conditions.




Dr Sarah Pollington
s.pollington@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

My main fields of research include ceramics and adhesive dentistry and I am an active member of the Oral Biomaterials Research Group at the School of Clinical Dentistry since 2002. I am involved in the development of novel glass-ceramics including manufacture and characterisation of various ceramics for use as indirect CAD/CAM core restorative materials and veneering ceramics. This work has concentrated on the production of materials with improved strength and durability. Other areas of research are the integrity of structurally compromised restored teeth and the clinical evaluation of restorative systems.

 

 

Professor Helen Rodd
h.d.rodd@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

My earliest work was in the field of neuroscience, where I used the human tooth pulp as a model to gain greater understanding into mechanisms of inflammatory pain. However, I then moved from basic science research to more social science research. I have focussed on the patient experience with particular emphasis on the impact of dental conditions, such as
traumatic dental injuries or enamel defects on children's oral health-related quality of life. I am also very involved in research to reduce children's dental anxiety through a guided self-help cognitive behavioural therapy approach. I work in a fantastic multi-disciplinary research team which aims to improve the oral health and treatment experiences of children and young people through a combination of clinical and social science research strategies. Our ethos is to engage children themselves in all our research and service development activities. To date, I have supervised 10 PhDs, 2 MPhils and 11 Masters to completion which have mostly had a child-centred theme.

My current research programme is driven by Health and Social policy which have highlighted the need to be more inclusive of children in decisions about their healthcare, as well as involving them more actively in health-related research and service development. In line with this, a key research objective is to develop robust patient-centred clinical outcome measures for use in dentistry. These will have important application within the NHS in determining the benefits of various treatment modalities in order to more effectively direct resource allocation.

I work within a unique multi-disciplinary research group at the University of 91直播, the ‘Person Centered and Population Oral Health’ group, which includes researchers across several clinical specialities and social sciences. The group conducts and implements high quality research in oral health, utilising the theories and empirical traditions of dental public health, sociology and psychology and a range of methodologies.

 

 

Dr Joey Shepherd
j.shepherd@sheffield.ac.uk


School of Clinical Dentistry

Research interests

My current research interests are largely translational and interdisciplinary in nature and lie primarily in novel approaches to a) the acceleration of wound healing, and b) detecting, preventing and treating bacterial infections (especially biofilm) without traditional use of antibiotics due to the rise in antimicrobial resistance. These include the use of polymer-based systems, ultrasound and acoustic vibration, novel wound dressings, antimicrobial biomaterials for dentistry, bone, skin and cornea and using 3D tissue engineered models to examine effects of planktonic and biofilm infection and treatment on both bacteria and human cells.

 

 

Professor Graham Stafford
G.Stafford@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests


My Group takes a multidisciplinary approach to investigating a range of biological problems ranging from basic biology to prototype translational projects.  There are several areas of research within the group which centres around the study of human pathogens with an overall aim at understanding microbial disease processes and exploiting the knowledge we generate for translational purposes wherever possible.

Bacteriophage biology:

Since 2016 the group have embarked on a programme of bacteriophage studies targeting a range of AMR (AntiMicrobial Resistant) pathogens including several of ESKAPE pathogens (Enterococci, Staphylococci, Klebsiella, ESBL etc)  as well as oral bacteria (Streptococci and Enterococci).

In recent years we have focused on isolation and characterisation of bacteriophage targeting pathogens from  a range of hard to treat Diabetic Foot Ulcer infections- which we call the DiaPhage project..  We aim to both understand the biology of these phages and their interactions with their bacterial hosts as well as working with clinical colleagues to develop them into viable novel antimicrobial treatments to cure DFU and other human infections.  We use a combination of genomics, biochemistry, structural biology and antibiotic resistance assays. 

 

The work is conducted in collaboration with colleagues from the faculty of science as well as clinical colleagues from 91直播 Teaching Hospitals trust.

Oral microbiology:

Our main focus is aimed at understanding the fundamental biology of bacteria residing in the oral cavity.  These studies have focused in several areas:

-        Biology of periodonatal pathogens: aimed at understanding how these bacteria interact with each other, human cells and within biofilms with a focus on glycobiology and innate immune modulation

-        Functional understanding of the oral microbiome: in collaboration with oral consumer product companies we focus on understanding how the composition and metabolism of the oral microbiome is influenced by nutrients, oral antimicrobial products.  We use a combination of nanopore based microbiome sequencing and metaproteomics (in collaboration with colleagues in the faculty of Engineeering).

The group  employ a variety of genetic and biochemical techniques while in collaboration with colleagues in the faculty of Medicine, faculty of Science and Faculty of Engineering to answer key questions within our areas of interest.

 

 

Dr Vitor de Carvalho Moreno das Neves
v.neves@sheffield.ac.uk
Personal Webpage

School of Clinical Dentistry

Research interests

I am a specialist in Periodontology, with a MSc and PhD in Translational & Regenerative Dentistry. I am qualified in Brazil and in the UK, with over a decade of experience in clinical and research environments.

I have been dedicating my life to understand the body biology, so that new oral health interventions are fully based on the natural biological processes of body. I have a strong track record of restorative dentistry research, having completed my PhD (2014-2018), supervised by Professor Paul Sharpe, on operative dentistry biology, which produced high impact research on dental pulp stem cell biology. My research has the potential to transform the way that teeth cavities are treated in the future, making current filling strategies obsolete. Additionally, during my NIHR Academic Clinical Lectureship (2019-2023), I developed periodontal research with focus on ageing and glucose metabolism, by using an array of research methodologies, such as pre-clinical, computational biology, microbiological sequencing, and clinical research. I administrated an international research group based in the UK and in Brazil, which together achieved excellent results repurposing Metformin as new drug for the management of periodontal disease. My work was awarded the 2022 Sir Wilfred Fish Prize (BSP) and received attention from national and international media outlets. My focus will be to continue these lines of research bringing positive media attention to the cutting-edge research taking place at your university and building new and beneficial collaborations within and outside the University.

My career ambition is to shape the future of Dentistry via molecular biology, genetics and epigenetics, developing techniques that are industry viable and affordable for the general public. The dream being to help patients to naturally grow and repair their own oral tissues and organs.