Rheumatoid arthritis
The DSU has written reports for a number of NICE Technology Appraisals in the disease area rheumatoid arthritis (RA).
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Rheumatoid arthritis – adlimumab, etanercept, infliximab, certolizumab pegol, golumumab, abatacept and tocilizumab [in progress, ID537]
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TA247 Tocilizumab for the treatment of rheumatoid arthritis (rapid review of TA198) (February 2012)
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TA198 Tocilizumab for the treatment of rheumatoid arthritis (August 2010) replaced by TA247
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Rheumatoid arthritis – adlimumab, etanercept and infliximab (sequential use) (suspended)
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TA130 Adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis (October 2007)
Adalimumab, Etanercept, Infliximab, Certolizumab Pegol, Golimumab, Abatacept and Tocilizumab
NICE appraisal
[in progress, ID537]
DSU report
Progression of disease in people with rheumatoid arthritis treated with non biologic therapies (PDF, 1.3MB) (February 2015)
Access , including the DSU’s response to comments on the above report.
Tocilizumab (rapid review)
NICE appraisal
(February 2012)
DSU report
Tocilizumab for the treatment of rheumatoic arthritis (PDF, 230KB) (September 2011)
Tocilizumab
NICE appraisal
TA198 Tocilizumab for the treatment of rheumatoid arthritis (August 2010) replaced by TA247
DSU report
Tocilizumab for the treatment of rheumatoid arthritis (PDF, 697KB) (May 2010)
Adalimumab, Etanercept and Infliximab (sequential use)
NICE appraisal
Rheumatoid arthritis – adalimumab, etanercept and infliximab (sequential use) (suspended)
DSU report
The sequential use of TNF-a inhibitors – update to a report by the decision support unit (PDF, 395KB) (January 2008)
The effectiveness of non biologic DMARDs after anti TNF-a inhibitor failure (PDF, 205KB) (January 2008)
Related publication
S Lloyd, S Bujkiewicz, A Wailoo, A Sutton, D Scott. . Rheumatology 2010; Vol 49 (12): 2313-2321.
Adalimumab, Etanercept and Infliximab
NICE appraisal
(October 2007)
DSU report
Sequential use of TNF-a inhibitors for the treatment of rheumatoid arthritis (PDF, 213KB) (August 2006)