Professor Jim Litster
School of Chemical, Materials and Biological Engineering
Professor of Chemical and Pharmaceutical Engineering
+44 114 222 7592
Full contact details
School of Chemical, Materials and Biological Engineering
Sir Robert Hadfield Building
Mappin Street
91Ö±²¥
S1 3JD
- Profile
-
I joined the Department in January 2016. Prior to my appointment, I was Professor of Chemical Engineering and Professor of Industrial and Physical Pharmacy at Purdue University in the USA for over eight years. I also spent 20 years in academic positions at The University of Queensland in Australia including Head of Chemical Engineering and Head of School of Engineering.
My research area is Particulate Products and Processes. My expertise is on wet granulation with over 30 years of experience in the field. My key contributions include the development of key regime maps for granulation processes and the development of mathematical models for engineering design and scaling of granulation processes. I'm the co-author of the well-known monograph in this area - The Science and Engineering of Granulation Processes and my approaches are now widely used in engineering practice in industry.
I was elected a Fellow of the Australian Academy of Technological Sciences and Engineering in 2010, and was awarded the Thomas Barron Award in Fluid-Particle Systems from the American Institute of Chemical Engineers in 2012, and Pharmaceutical Section Award for contributions to Quality by Design by the American Institute of Chemical Engineers.
I'm passionate about university education and educators. One of my most significant achievements is leading the design and implementation of a new Project Centered Curriculum across the whole Chemical Engineering Program at UQ between 1998 and 2005. This transformation was recognized as a world leading effort and received many awards, including the Australian Award for University Teaching in 2005, and one of six engineering change programs highlighted in the Royal Academy Of Engineering/MIT report on Achieving excellence in engineering: the ingredients of successful change (2012).
- Research interests
-
Predicting the structure of complex particulate products and their performance in use is a grand challenge in engineering science. The products include pharmaceuticals (e.g. GSK, Astra Zeneca), consumer products (e.g. P&G, Unilever), agricultural chemicals (e.g. Syngenta) and foods (e.g. Nestle). The value of sales and export of these high value products for the UK is estimated at £180bn per year (Chemistry Innovation KTN Strategy Report 2010) and complex products are a designated priority area in the Innovate UK High Value Manufacturing strategy. The performance of these products is controlled by their size, structure and surface properties, as well as their chemistry. Therefore, modeling the development of these attributes must address structure at many length scales from nm to mm. Jim’s programme focuses on developing new design models to substantially improve the manufacture of these particulate products.
- Publications
-
Books
- Preface.
- Design and Processing of Particulate Products. Cambridge University Press.
- . Springer Netherlands.
Journal articles
- . Powder Technology, 120082-120082.
- . International Journal of Pharmaceutics, 659.
- . Journal of Pharmaceutical Innovation, 19(2).
- . International Journal of Pharmaceutics, 647, 123475-123475.
- . Powder Technology, 430.
- . International Journal of Pharmaceutics, 633.
- . Powder Technology, 417.
- . Chemical Engineering Science, 268, 118397-118397.
- . International Journal of Pharmaceutics, 628.
- . Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 478(2258).
- . Powder Technology, 398, 117134-117134.
- . Powder Technology, 396(Part A), 578-595.
- . Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 477(2252).
- . International Journal of Pharmaceutics, 607.
- . International Journal of Pharmaceutics, 120934-120934.
- . Powder Technology, 392, 157-166.
- . Journal of Drug Delivery Science and Technology, 102587.
- . Chemical Engineering Research and Design, 161, 95-102.
- . Powder Technology, 366, 144-149.
- . International Journal of Pharmaceutics, 578.
- . Powder Technology, 363, 525-540.
- . International Journal of Pharmaceutics, 573.
- . Advanced Powder Technology.
- . Chemical Engineering Science: X, 4.
- . Powder Technology, 355, 514-525.
- . Journal of Pharmaceutical Sciences, 107(10), 2581-2591.
- . Drug Development and Industrial Pharmacy, 1-33.
- . Powder Technology, 335, 62-69.
- . European Journal of Pharmaceutics and Biopharmaceutics, 128, 57-68.
- . Powder Technology, 326, 327-343.
- . Powder Technology.
- . CrystEngComm, 19(32), 4797-4806.
- . Powder Technology, 315, 290-299.
- . Crystal Growth & Design, 17(6), 3528-3537.
- . Crystal Growth & Design, 17(5), 2782-2791.
- . Crystal Growth & Design, 17(3), 1264-1275.
- . Organic Process Research & Development, 21(2), 187-194.
- . Powder Technology, 305, 19-26.
- . International Journal of Pharmaceutics, 513(1-2), 357-375.
- . Powder Technology, 299, 87-97.
- . AIChE Journal.
- . Powder Technology, 291, 487-498.
- . Powder Technology, 291, 328-336.
- . International Journal of Chemical Engineering, 2015, 1-7.
- . International Journal of Pharmaceutics, 496(1), 24-32.
- . Crystal Growth & Design, 15(8), 3645-3651.
- . Chemical Engineering Science, 125, 165-175.
- . Chemical Engineering Science, 125, 1-3.
- . Advanced Powder Technology, 26(2), 553-562.
- . Organic Process Research & Development, 19(1), 3-62.
- . Powder Technology, 270, 612-621.
- . Powder Technology, 270, 435-444.
- . Powder Technology, 264, 550-560.
- . Journal of Chemical & Engineering Data, 59(9), 2699-2703.
- . Journal of Colloid and Interface Science, 411, 265-272.
- . AIChE Journal, 59(11), 4100-4115.
- . Biotechnology Progress, 29(5), 1203-1211.
- . Journal of Pharmaceutical Innovation, 8(3), 147-162.
- . Journal of Pharmaceutical Innovation, 8(2), 90-98.
- . Chemical Engineering Science, 95, 360-365.
- . Chemical Engineering Science, 95, 203-210.
- . Powder Technology, 240, 1-1.
- . Powder Technology, 240, 66-73.
- . Powder Technology, 240, 7-18.
- . Powder Technology, 238, 108-115.
- . Journal of Colloid and Interface Science, 393, 369-376.
- . Powder Technology, 237, 386-399.
- . AIChE Journal, 59(1), 96-107.
- . Chemical Engineering Transactions, 32, 2077-2082.
- . AAPS PharmSciTech, 13(3), 1005-1012.
- . Advanced Powder Technology, 23(4), 454-458.
- . Powder Technology, 221, 90-100.
- . AIChE Journal, 58(5), 1397-1408.
- . Chemical Engineering Research and Design, 90(1), 158-161.
- . Biotechnology Progress, 28(1), 163-170.
- Examining the failure modes of wet granular materials using dynamic diametrical compression. Powder Technology.
- . Powder Technology, 224, 189-195.
- . International Journal of Pharmaceutics, 418(2), 254-264.
- . Powder Technology, 212(1), 69-79.
- . Chemical Engineering Science, 66(16), 3592-3604.
- . Chemical Engineering Transactions, 24, 631-636.
- Foreword. European Urological Review, 6(2), 1.
- . Chemical Engineering Science, 65(21), 5651-5657.
- . AIChE Journal, NA-NA.
- . Chemical Engineering Science, 64(15), 3407-3416.
- . Crystal Growth & Design, 9(5), 2198-2206.
- . Chemical Engineering Research and Design, 87(4), 598-614.
- . Journal of Process Control, 19(4), 615-622.
- . Chemical Engineering Science, 64(4), 775-786.
- . Powder Technology, 189(2), 158-164.
- . Powder Technology, 188(2), 89-101.
- . International Journal of Pharmaceutics, 362(1-2), 109-117.
- . Particle & Particle Systems Characterization, 25(3), 266-276.
- . Chemical Engineering Science, 63(5), 1315-1329.
- , 897-977.
- . Powder Technology, 179(1-2), 55-58.
- . Chemical Engineering Science, 62(17), 4802-4810.
- . Journal of Agricultural and Food Chemistry, 55(6), 2467-2473.
- . Powder Technology, 171(2), 96-105.
- . AIChE Journal, 53(2), 514-522.
- . Powder Technology, 170(2), 53-63.
- . Education for Chemical Engineers, 1(1), 39-48.
- . Chemical Engineering Research and Design, 84(7), 619-628.
- . Metallurgical and Materials Transactions B, 36(6), 755-764.
- . Chemical Engineering Science, 60(14), 3751-3761.
- Binder-treated segregation-free aluminum alloy powders. International Journal of Powder Metallurgy (Princeton, New Jersey), 41(1), 42-49.
- . Advanced Powder Technology, 15(4), 447-457.
- . Powder Technology, 143-144, 84-96.
- . Aiche Journal, 492(2), 350-361.
- . Powder Technology, 141(1-2), 20-30.
- . JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 37(2), 181-186.
- . Chemical Engineering Communications, 190(10), 1309-1334.
- . Metallurgical and Materials Transactions B, 34(2), 183-191.
- . Powder Technology, 130(1-3), 97-101.
- . Powder Technology, 130(1-3), 415-420.
- . Powder Technology, 130(1-3), 91-96.
- . Powder Technology, 130(1-3), 35-40.
- . Industrial & Engineering Chemistry Research, 42(3), 442-447.
- . Journal of Colloid and Interface Science, 253(2), 353-366.
- . Colloids and Surfaces A: Physicochemical and Engineering Aspects, 207(1-3), 89-104.
- . Chemical Engineering Science, 57(12), 2183-2191.
- . AIChE Journal, 48(5), 953-962.
- . Powder Technology, 124(3), 230-237.
- . Powder Technology, 124(3), 272-280.
- . Powder Technology, 124(3), 175-175.
- . Powder Technology, 123(2-3), 166-177.
- . Powder Technology, 117(1-2), 3-39.
- . Powder Technology, 117(1-2), 83-97.
- . Powder Technology, 114(1-3), 32-39.
- . ISIJ International, 41(1), 10-17.
- . Diamond and Related Materials, 9(3-6), 328-332.
- . Powder Technology, 108(2-3), 122-129.
- . AIChE Journal, 46(3), 529-539.
- . ISIJ International, 40(7), 627-636.
- . Chemical Engineering Science, 54(15-16), 3263-3271.
- . Biotechnology and Bioengineering, 63(4), 383-391.
3 N4 -bonded SiC bricks in blast furnace environment. Journal of Engineering and Applied Science, 38(12), 1326-1331.
High temperature behavior of Si - . Powder Technology, 99(3), 234-242.
- . Powder Technology, 99(3), 243-250.
- . AIChE Journal, 44(7), 1510-1518.
- . ISIJ International, 38(12), 1326-1331.
- . Metallurgical and Materials Transactions B, 28(4), 597-604.
- . Chemical Engineering Science, 52(21-22), 4013-4019.
- . Steel Research, 68(10), 434-440.
- Visualisation and maximum percolation velocity of non-wetting liquid flow through a 2-D packed bed. Scandinavian Journal of Metallurgy, 26(2), 79-84.
- . ISIJ International, 36(1), 32-39.
- . Powder Technology, 88(2), 165-172.
- . Powder Technology, 88(1), 65-70.
- . Powder Technology, 88(1), 15-20.
- . Drying Technology, 13(5-7), 1261-1278.
- . Drying Technology, 13(3), 737-751.
- . Computers & Chemical Engineering, 19(4), 383-393.
- . AIChE Journal, 41(3), 591-603.
- . Powder Technology, 82(1), 37-49.
- . International Journal of Mineral Processing, 41(1-2), 53-69.
- . International Journal of Mineral Processing, 42(1-2), 37-52.
- . Drying Technology, 11(7), 1641-1656.
- . Chemical Engineering Science, 48(23), 3951-3961.
- . Powder Technology, 74(3), 259-270.
- . Powder Technology, 74(3), 215-230.
- . Powder Technology, 66(1), 59-67.
- Resource based education for training chemical engineers. CEA : chemical engineering in Australia, 15(2), 15-17.
- . Powder Technology, 62(2), 125-134.
- . ISIJ International, 29(4), 274-283.
- . Fuel, 67(10), 1327-1330.
- . Powder Technology, 55(2), 141-151.
- . Transactions of the Iron and Steel Institute of Japan, 27(1), 3-9.
- . Transactions of the Iron and Steel Institute of Japan, 26(8), 704-709.
- . Transactions of the Iron and Steel Institute of Japan, 26(12), 1036-1044.
- FUNDAMENTALS OF GRANULATION OF IRON ORE FOR FERROUS SINTER PRODUCTION., 72-77.
- MEASURING THE STRENGTH OF AGGLOMERATE MATERIALS., 118-123.
- . Separation Science and Technology, 16(10), 1339-1354.
- . CrystEngComm, 17(6), 1242-1248.
- . CrystEngComm, 15(12), 2197-2205.
- . Engineering.
- . Chemical Engineering Science: X, 4.
- Efficient Global Sensitivity-Based Model Calibration of a High-Shear Wet Granulation Process. Chemical Engineering Science.
Chapters
- , Computer Aided Chemical Engineering (pp. 697-702). Elsevier
- , Handbook of Pharmaceutical Granulation Technology (pp. 705-743).
- , Continuous Pharmaceutical Processing (pp. 269-300). Springer International Publishing
- , Predictive Modeling of Pharmaceutical Unit Operations (pp. 99-135). Elsevier
- , Predictive Modeling of Pharmaceutical Unit Operations (pp. ix-xi). Elsevier
- , Predictive Modeling of Pharmaceutical Unit Operations (pp. xiii-xxiv). Elsevier
- , Predictive Modeling of Pharmaceutical Unit Operations (pp. 99-135).
- Scale-Up considerations in granulation, Handbook of Pharmaceutical Granulation Technology (pp. 538-566).
- Design and Processing of Particulate Products Introduction, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 1-8).
- Aerosol Processes, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 161-191).
- Industrial Crystallization, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 80-116).
- Dispersion, Disintegration, and Dissolution, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 294-321).
- Design and Processing of Particulate Products Preface, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. XIII-XIV).
- Particle Size Reduction, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 117-160).
- Particle Characterization and Particle Property Distributions, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 9-45).
- The Population Balance, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 46-79).
- Strength, Breakage, and Attrition of Particulate Delivery Forms, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 273-293).
- Spray Drying and Spray Cooling, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 192-227).
- Wet Granulation, DESIGN AND PROCESSING OF PARTICULATE PRODUCTS (pp. 228-272).
- Chapter 25 Scale Up Considerations in Granulation In Parikh D (Ed.), Handbook of Pharmaceutical Granulation Technology, Third Edition CRC Press
- Granulation Rate Processes, GRANULATION (pp. 897-977).
- , Drugs and the Pharmaceutical Sciences (pp. 459-490). Informa Healthcare
- , Chemical Engineering in the Pharmaceutical Industry (pp. 147-171). John Wiley & Sons, Inc.
- , Chemical Engineering in the Pharmaceutical Industry (pp. 757-780). John Wiley & Sons, Inc.
Conference proceedings papers
- A New Curriculum to Train Chemical Engineers to Solve 21st Century Grand Challenges. 5 TH Annual Symposium of the United Kingdom & Ireland Engineering Education Research Network:
- Kinetics of immersion nucleation driven by surface tension.. 7th International Granulation Workshop. 91Ö±²¥, UK, 1 July 2015 - 3 July 2015.
- Characterization of distributive mixing elements and effect of downstream conveying elements in twin screw granulation. Particle Technology Forum 2014 - Core Programming Area at the 2014 AIChE Annual Meeting (pp 251-260)
- Modeling drug precipitation in the human gastrointestinal tract using gCOAS. Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future (pp 75-76)
- Purdue's Engineer of 2020: The journey. ASEE Annual Conference and Exposition, Conference Proceedings
- Dynamic modelling of particle-droplet collisions. AIChE Annual Meeting, Conference Proceedings
- Crystallization of pharmaceuticals via microfluidic crystallization. AIChE Annual Meeting, Conference Proceedings
- A combined mechanistic model for nucleation, aggregation and breakage in a population balance model of granulation. AIChE Annual Meeting, Conference Proceedings
- A mechanistic model for nucleation and aggregation in population balances of granulation: Batch characterisation studies and experimental validation. AIChE Annual Meeting, Conference Proceedings
- Correlating molecular interactions with solubility of alpha-amylase from bacillus licheniformis. AIChE Annual Meeting, Conference Proceedings
- Effect of other protein on the solubility of hen egg white lysozyme. AIChE Annual Meeting, Conference Proceedings
- Influence of surface tack of food products on agglomeration in spray drying. AIChE Annual Meeting, Conference Proceedings
- Kinetics and modeling of crystallization in surfactant-free monodisperse emulsions. AIChE Annual Meeting, Conference Proceedings
- The attrition and breakage propensity of some industrially crystallized materials. AIChE Annual Meeting, Conference Proceedings
- Dynamic mechanical properties of partially saturated granules. AIChE Annual Meeting, Conference Proceedings
- Wet granule breakage in high shear mixer granulation. AIChE Annual Meeting, Conference Proceedings (pp 3010)
- Crystallization in monodisperse emulsions. AIChE Annual Meeting, Conference Proceedings (pp 2410)
- Modelling of the Blast Furnace Lower Zone for design of High Rate Fuel Injectant Practices. 2nd International Congress on the Science and Technology of Ironmaking and 57th Ironmaking Conference Proceedings (pp 319-331)
- Determination and Significance of Parameters in the Modeling of Liquid Flow in the Blast Furnace Lower Zone. 2nd International Congress on the Science and Technology of Ironmaking and 57th Ironmaking Conference Proceedings (pp 293-299)
- . MRS Proceedings, Vol. 495
- . MRS Proceedings, Vol. 416
- Effect of process variables on the maximum coating rate in a spouted bed seed coater. CHEMECA '90, Australasian Chemical Engineering Conference (pp 626-633)
- Modelling of fertilizer granulation using population balance techniques. CHEMECA '90, Australasian Chemical Engineering Conference (pp 642-649)
- ASPECTS OF PARTICLE SIZE IN THE PROCESSING OF OIL SHALE.. National Conference Publication - Institution of Engineers, Australia(82 /9) (pp 46-50)
- ROLE OF KINETICS IN OIL SHALE RETORTING.. National Conference Publication - Institution of Engineers, Australia(82 /9) (pp 35-39)
- . 2009 Annual Conference & Exposition Proceedings, 14 June 2009 - 17 June 2009.
Datasets
Presentations